Book contents
- Perinatal Neuropathology
- Perinatal Neuropathology
- Copyright page
- Contents
- Preface
- Acknowledgments
- Abbreviations
- Section I Techniques and Practical Considerations
- Section 2 Human Nervous System Development
- Section 3 Stillbirth
- Section 4 Disruptions / Hypoxic-Ischemic Injury
- Section 5 Malformations
- Neural Tube Defects and Patterning Defects
- Hydrocephalus
- Chapter 39 Fetal and Perinatal Hydrocephalus
- Neuronal Migration Disorders
- Genetic Syndromes and Phakomatoses
- Section 6 Perinatal Neurooncology
- Section 7 Spinal and Neuromuscular Disorders
- Section 8 Eye Disorders
- Section 9 Infections: In Utero Infections
- Section 10 Metabolic / Toxic Disorders: Storage Diseases
- Section 11 Forensic Neuropathology
- Appendix 1 Technical Considerations in Perinatal CNS
- Index
- References
Chapter 39 - Fetal and Perinatal Hydrocephalus
from Hydrocephalus
Published online by Cambridge University Press: 07 August 2021
- Perinatal Neuropathology
- Perinatal Neuropathology
- Copyright page
- Contents
- Preface
- Acknowledgments
- Abbreviations
- Section I Techniques and Practical Considerations
- Section 2 Human Nervous System Development
- Section 3 Stillbirth
- Section 4 Disruptions / Hypoxic-Ischemic Injury
- Section 5 Malformations
- Neural Tube Defects and Patterning Defects
- Hydrocephalus
- Chapter 39 Fetal and Perinatal Hydrocephalus
- Neuronal Migration Disorders
- Genetic Syndromes and Phakomatoses
- Section 6 Perinatal Neurooncology
- Section 7 Spinal and Neuromuscular Disorders
- Section 8 Eye Disorders
- Section 9 Infections: In Utero Infections
- Section 10 Metabolic / Toxic Disorders: Storage Diseases
- Section 11 Forensic Neuropathology
- Appendix 1 Technical Considerations in Perinatal CNS
- Index
- References
Summary
Hydrocephalus is defined as active distension of the brain’s ventricular system caused by the inadequate passage of cerebrospinal fluid (CSF) from its point of production to its point of absorption (1). It must be distinguished from the passive expansion of the ventricles secondary to the destruction of the brain (e.g., hydrocephalus ex vacuo or hydranencephaly). Although hydrocephalus can occur at any age, here we focus on the pathology in fetuses and infants (2). Enlargement of the cerebral ventricles is common, multifactorial, and non-specific. When identified on prenatal ultrasound, elective termination of a pregnancy may be recommended (3). Subtle enlargement of the ventricles is difficult to verify in brains of stillborn infants because the brains are very soft.
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- Perinatal Neuropathology , pp. 231 - 242Publisher: Cambridge University PressPrint publication year: 2021