Scottish Intercollegiate Guidelines Network (SIGN). Prevention and Management of Venous Thromboembolism: A National Clinical Guideline. NHS Quality Improvement Scotland, 2010. Update October 2014.Google Scholar

Royal College of Obstetricians and Gynaecologists. Reducing the Risk of Venous Thrombo-embolism During Pregnancy and the Puerperium. Green-top Guideline No. 37a. London: RCOG, 2015.Google Scholar

Royal College of Obstetricians and Gynaecologists. Thrombosis and Embolism During Pregnancy and the Puerperium: Acute Management. Green-top Guideline No. 37b. London: RCOG, 2015.Google Scholar

Royal College of Obstetricians and Gynaecologists. Providing Quality Care for Women Framework for Maternity Services Standard. London: RCOG, 2016.Google Scholar

Cathy Nelson-Piercy on behalf of the MBRRACEUK Thrombosis and Thromboembolism chapter writing group. Prevention and treatment of thrombosis and thromboembolism. In Knight, M, Tuffnell, D, Kenyon, S, Shakespeare, J, Gray, R, Kurinczuk, JJ (eds) on behalf of MBRRACE-UK. Saving Lives, Improving Mothers’ Care: Surveillance of Maternal Deaths in the UK 2011–13 and Lessons Learned to Inform Maternity Care from the UK and Ireland Confidential Enquiries into Maternal Deaths and Morbidity 2009–13. Oxford: National Perinatal Epidemiology Unit, University of Oxford 2015 ;42–52.Google Scholar

Mahmood, T, Owen, P, Arulkumaran, S, Dhillon, C (eds). Models of Care in Maternity Services. London: RCOG, 2010.Google Scholar

Mol, BWJ, Roberts, CT, Thangaratinam, S, Magee, LA, de Groot, CJM, Hofmeyr, GJ. Pre-eclampsia. Lancet. 2016; 387(10022):999–1011.CrossRefGoogle ScholarPubMed

Steegers, EA, von Dadelszen, P, Duvekot, JJ, Pijnenborg, R. Pre-eclampsia. Lancet. 2010;376(9741):631–44.Google Scholar

Hutcheon, JA, Lisonkova, S, Joseph, KS. Epidemiology of pre-eclampsia and the other hypertensive disorders of pregnancy. Best Pract Res Clin Obstet Gynaecol. 2011; 25(4):391–403.CrossRefGoogle ScholarPubMed

Brown, MA, Magee, LA, Kenny L, , Karumanchi, SA, McCarthy, F, Saito, S, et al. The hypertensive disorders of pregnancy: ISSHP classification, diagnosis and management recommendations for international practice 2018. Pregnancy Hypertens. 2018;13:291–310.CrossRefGoogle Scholar

Magee, LA, Pels, A, Helewa, M, Rey, E, von Dadelszen, P. Diagnosis, evaluation, and management of the hypertensive disorders of pregnancy. Pregnancy Hypertens. 2014;4(2):105–45.Google Scholar

Burke, O, Benton, S, Szafranski, P, von Dadelszen, P, Buhimschi, SC, Cetin, I, et al. Extending the scope of pooled analyses of individual patient biomarker data from heterogeneous laboratory platforms and cohorts using merging algorithms. Pregnancy Hypertens. 2016;6(1):53–9.CrossRefGoogle ScholarPubMed

Staff, AC, Burke, O, Benton, S, von Dadelszen, P, Szafranski, P, Zhang, C, et al. Maternal circulating PlGF concentrations and placenta-related pregnancy complications: First results from the CoLab AngF Study. Pregnancy Hypertens. 2013;3(2):59.Google Scholar

Staff, AC, Benton, SJ, von Dadelszen, P, Roberts, JM, Taylor, RN, Powers, RW, et al. Redefining preeclampsia using placenta-derived biomarkers. Hypertension. 2013;61(5):932–942.Google Scholar

Ukah, UV, Mbofana, F, Manriquez Rocha, B, Loquiha, O, Mudenyanga, C, Usta, M et al. The diagnostic performance of placental growth factor in women with suspected preeclampsia attending antenatal facilities in Maputo, Mozambique. Hypertension. 2017;69(3):469–74.Google Scholar

Gillon, TE, Pels, A, von Dadelszen, P, MacDonell, K, Magee, LA. Hypertensive disorders of pregnancy: a systematic review of international clinical practice guidelines. PLoS ONE. 2014;9(12):e113715.CrossRefGoogle ScholarPubMed

Whelton, PK, Carey, RM, Aronow, WS, Casey, DE, Jr., Collins, KJ, Dennison, HC, et al. ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Hypertension. 2018;71(6):1269–1324.Google Scholar

Waugh, JJ, Gupta, M, Rushbrook, J, Halligan, A, Shennan, AH. Hidden errors of aneroid sphygmomanometers. Blood Press Monit. 2002;7(6):309–12.Google Scholar

Natarajan, P, Shennan, AH, Penny, J, Halligan, AW, de Swiet, M, Anthony, J. Comparison of auscultatory and oscillometric automated blood pressure monitors in the setting of preeclampsia. Am J Obstet Gynecol. 1999;181(5 Pt 1):1203–10.Google Scholar

MacDorman, MF, Declercq, E, Cabral, H, Morton, C. Recent increases in the U.S. maternal mortality rate: disentangling trends from measurement issues. Obstet Gynecol. 2016;128(3):447–55.CrossRefGoogle ScholarPubMed

Pattinson, RC, Bergh, AM, Ameh, C, Makin, J, Pillay, Y, Van den Broek, N, et al. Reducing maternal deaths by skills-and-drills training in managing obstetric emergencies: a before-and-after observational study. S Afr Med J. 2019;109(4):241–5.CrossRefGoogle ScholarPubMed

Council on Patient Safety in Women’s Health Care. Safe health care for every woman. 2018. 9–2-2018. https://safehealthcareforeverywoman.org/patient-safety-bundles/severe-hypertension-in-pregnancy/Google Scholar

Payne, BA, Hutcheon, JA, Ansermino, JM, Hall, DR, Bhutta, ZA, Bhutta, SZ, et al. A risk prediction model for the assessment and triage of women with hypertensive disorders of pregnancy in low-resourced settings: the miniPIERS (Pre-eclampsia Integrated Estimate of RiSk) multi-country prospective cohort study. PLoS Med. 2014;11(1):e1001589.CrossRefGoogle ScholarPubMed

Payne, B, Hodgson, S, Hutcheon, JA, Joseph, KS, Li, J, Lee, T, et al. Performance of the fullPIERS model in predicting adverse maternal outcomes in pre-eclampsia using patient data from the PIERS (Pre-eclampsia Integrated Estimate of RiSk) cohort, collected on admission. BJOG. 2013;120(1):113–18.CrossRefGoogle ScholarPubMed

Akkermans, J, Payne, B, von Dadelszen, P, Groen, H, de Vries, J, Magee, LA, et al. Predicting complications in pre-eclampsia: external validation of the fullPIERS model using the PETRA trial dataset. Eur J Obstet Gynecol Reprod Biol. 2014;179:58–62.Google Scholar

Ukah, UV, Payne, B, Lee, T, Magee, LA, von Dadelszen, P. External validation of the fullPIERS model for predicting adverse maternal outcomes in pregnancy hypertension in low- and middle-income countries. Hypertension. 2017;69(4):705–11.Google Scholar

Ukah, UV, Payne B, Hutcheon JA, Ansermino JM, Ganzevoort W, Thangaratinam S, Magee LA, von Dadelszen P. Assessment of the fullPIERS Risk Prediction Model in Women With Early-Onset Preeclampsia. Hypertension. 2018 Apr;71(4):659–665. doi: 10.1161/HYPERTENSIONAHA.117.10318. Epub 2018 Feb 12.Google Scholar

Payne, BA, Ryan, H, Bone, J, Magee, LA, Aarvold, AB, Ansermino, JM, et al. Development and internal validation of the multivariable CIPHER (Collaborative Integrated Pregnancy High-dependency Estimate of Risk) clinical risk prediction model. Crit Care. 2018;22(1):278.Google Scholar

Dawes, GS, Moulden, M, Redman, CW. Short-term fetal heart rate variation, decelerations, and umbilical flow velocity waveforms before labor. Obstet Gynecol. 1992;80(4):673–8.Google ScholarPubMed

Street, P, Dawes, GS, Moulden, M, Redman, CW. Short-term variation in abnormal antenatal fetal heart rate records. Am J Obstet Gynecol. 1991;165(3):515–23.Google Scholar

Baschat, AA, Cosmi, E, Bilardo, CM, Wolf, H, Berg, C, Rigano, S, et al. Predictors of neonatal outcome in early-onset placental dysfunction. Obstet Gynecol. 2007;109(2 Pt 1):253–61.Google Scholar

Ferrazzi, E, Bozzo, M, Rigano, S, Bellotti, M, Morabito, A, Pardi, G, et al. Temporal sequence of abnormal Doppler changes in the peripheral and central circulatory systems of the severely growth-restricted fetus. Ultrasound Obstet Gynecol. 2002;19(2):140–6.CrossRefGoogle ScholarPubMed

Hecher, K, Bilardo, CM, Stigter, RH, Ville, Y, Hackeloer, BJ, Kok, HJ, et al. Monitoring of fetuses with intrauterine growth restriction: a longitudinal study. Ultrasound Obstet Gynecol. 2001;18(6):564–70.Google Scholar

Ribbert, LS, Snijders, RJ, Nicolaides, KH, Visser, GH. Relation of fetal blood gases and data from computer-assisted analysis of fetal heart rate patterns in small for gestation fetuses. Br J Obstet Gynaecol. 1991;98(8):820–3.Google Scholar

Odendaal, HJ, Pattinson, RC, Bam, R, Grove, D, Kotze, TJ. Aggressive or expectant management for patients with severe preeclampsia between 28–34 weeks’ gestation: a randomized controlled trial. Obstet Gynecol. 1990;76(6):1070–5.Google Scholar

Sibai, BM, Mercer, BM, Schiff, E, Friedman, SA. Aggressive versus expectant management of severe preeclampsia at 28 to 32 weeks’ gestation: a randomized controlled trial. Am J Obstet Gynecol. 1994;171(3):818–22.Google Scholar

Magee, LA, Yong, PJ, Espinosa, V, Cote, AM, Chen, I, von Dadelszen, P. Expectant management of severe preeclampsia remote from term: a structured systematic review. Hypertens Pregnancy. 2009;28(3):312–47.Google Scholar

Broekhuijsen, K, van Baaren, GJ, van Pampus, MG, Ganzevoort, W, Sikkema, JM, Woiski, MD, et al. Immediate delivery versus expectant monitoring for hypertensive disorders of pregnancy between 34 and 37 weeks of gestation (HYPITAT-II): an open-label, randomised controlled trial. Lancet. 2015;385(9986):2492–501.CrossRefGoogle ScholarPubMed

Koopmans, CM, Bijlenga, D, Groen, H, Vijgen, SM, Aarnoudse, JG, Bekedam, DJ, et al. Induction of labour versus expectant monitoring for gestational hypertension or mild pre-eclampsia after 36 weeks’ gestation (HYPITAT): a multicentre, open-label randomised controlled trial. Lancet. 2009;374(9694):979–88.Google Scholar

Alanis, MC, Robinson, CJ, Hulsey, TC, Ebeling, M, Johnson, DD. Early-onset severe preeclampsia: induction of labor vs elective cesarean delivery and neonatal outcomes. Am J Obstet Gynecol. 2008;199(3):262–6.CrossRefGoogle ScholarPubMed

Li, H, Gudmundsson, S, Olofsson, P. Prospect for vaginal delivery of growth restricted fetuses with abnormal umbilical artery blood flow. Acta Obstet Gynecol Scand. 2003;82(9):828–33.CrossRefGoogle ScholarPubMed

Deruelle, P, Coudoux, E, Ego, A, Houfflin-Debarge, V, Codaccioni, X, Subtil, D. Risk factors for post-partum complications occurring after preeclampsia and HELLP syndrome: a study in 453 consecutive pregnancies. Eur J Obstet Gynecol.Reprod Biol. 2006;125(1):59–65.Google Scholar

Jacobsen, AF, Skjeldestad, FE, Sandset, PM. Ante- and postnatal risk factors of venous thrombosis: a hospital-based case-control study. J Thromb Haemost. 2008;6(6):905–12.CrossRefGoogle ScholarPubMed

Raheem, IA, Saaid, R, Omar, SZ, Tan, PC. Oral nifedipine versus intravenous labetalol for acute blood pressure control in hypertensive emergencies of pregnancy: a randomised trial. BJOG. 2012;119(1):78–85.Google Scholar

Drugs and Lactation Database (LactMed). 9–2-2018. Washington, DC, US Library of Medicine. www.ncbi.nlm.nih.gov/books/NBK501922/Google Scholar

Duley, L, Gulmezoglu, AM, Henderson-Smart, DJ, Chou, D. Magnesium sulphate and other anticonvulsants for women with pre-eclampsia. Cochrane Database Syst Rev. 2010;(11):CD000025.Google Scholar

Ramos-Santos, E, Devoe, LD, Wakefield, ML, Sherline, DM, Metheny, WP. The effects of epidural anesthesia on the Doppler velocimetry of umbilical and uterine arteries in normal and hypertensive patients during active term labor. Obstet Gynecol. 1991;77(1):20–6.Google Scholar

MBRRACE- UK. Saving lives, improving mother’s care: surveillance of maternal deaths in the UK 2012–2014 and lessons learned to inform maternity care from the UK and Ireland Confidential Enquiries into Maternal Deaths and Morbidity. 2009–2014.Google Scholar

Chandraharan, E, Arulkumaran, S. Management algorithm for atonic postpartum haemorrhage. J Paediatr Obstet Gynaecol. 2005;June:106–12.Google Scholar

Chandraharan, E, Arulkumaran, S. Massive postpartum haemorrhage and management of coagulopathy. Obstet Gynaecol Reprod Med. 2007;17:119–22.Google Scholar

Royal College of Obstetricians and Gynaecologists. Prevention and Management of Postpartum Haemorrhage. Green-top Guideline No. 52. London: RCOG, 2016.Google Scholar

Condous, GS, Arulkumaran, S, Symonds, I, et al. The tamponade test for massive postpartum haemorrhage. Obstet Gynecol. 2003;104:767–72.Google Scholar

Chandraharan, E, Arulkumaran, S. Surgical aspects of postpartum haemorrhage. Best Pract Res Clin Obstet Gynaecol. 2008;22(6):1089–102.Google Scholar

Ratnam, LA, Gibson, M, Sandhu, C, et al. Transcatheter pelvic arterial embolisation for control of obstetric and gynaecological haemorrhage. J Obstet Gynaecol. 2008;28 (6):573–9.Google Scholar

Pinas, A, Chandraharan, E. Postpartum haemorrhage and haematological management. Obstet Gynaecol Reprod Med. 2014;24:291–5.Google Scholar

NICE. Guideline NG51. Sepsis: Recognition, Diagnosis and Early Management, updated April 2019.Google Scholar

MBRRACE-UK. Saving lives, improving mother’s care: Lessons learned to inform maternity care from the UK and Ireland Confidential Enquiries into Maternal Deaths and Morbidity 2014–16.Google Scholar

Acosta, CD, Kurinczuk, JJ, Lucas, DN, Tuffnell, DJ, Sellers, S, Knight, M, United Kingdom Obstetric Surveillance System. Severe maternal sepsis in the UK, 2011–2012: a national case-control study. PLoS Med. 2014;11(7):e1001672.Google Scholar

Knight, M, Tuffnell, D, Brocklehurst, P, Spark, P, Kurinczuk, JJ, on behalf of the UK Obstetric Surveillance System. Incidence and risk factors for amniotic fluid embolism. Obstet Gynecol. 2010;115:910–17.Google Scholar

Knight, M, Nair, M, Tuffnell, D, Shakespeare, J, Kenyon, S, Kurinczuk, JJ (eds) on behalf of MBRRACE-UK. Saving Lives, Improving Mothers’ Care: Lessons Learned to Inform Maternity Care from the UK and Ireland Confidential Enquiries into Maternal Deaths and Morbidity 2013–15. Oxford: National Perinatal Epidemiology Unit, University of Oxford, 2017.Google Scholar

Roberts, C, Algert, C, Knight, M, Morris, J. Amniotic fluid embolism in an Australian population-based cohort. Br J Obstet Gynaecol. 2010;117:1417–21.Google Scholar

Kramer, MS, Rouleau, J, Baskett, TF, Joseph, KS; Maternal Health Study Group of the Canadian Perinatal Surveillance System. Amniotic-fluid embolism and medical induction of labour: a retrospective, population-based cohort study. Lancet. 2006;368:1444–8.Google Scholar

Centre for Maternal and Child Enquiries (CMACE). Saving mothers’ lives: Report on Confidential Enquiries into Maternal Deaths in the United Kingdom. Br J Obstet Gynaecol. 2011;118 (Suppl. 1):1–208.Google Scholar

Howell, C, Grady, K, Cox, C. Managing Obstetric Emergencies and Trauma: The MOET Course Manual, 2nd ed. London: RCOG, 2007.Google Scholar

Conde-Agudelo, A, Romero, R. Amniotic fluid embolism: an evidence-based review. Am J Obstet Gynecol, 2009;201(5):445.e1–13. Erratum in Am J Obstet Gynecol. 2010;202(1):92.Google Scholar

Tuffnell, D, Knight, M, Plaat, F. Amniotic fluid embolism: An update. Anaesthesia. 2011;66(1):3–6.Google Scholar

Tuffnell, DJ. United Kingdom amniotic fluid embolism register. Br J Obstet Gynaecol. 2005;112:1625–9.Google Scholar

Beckett, VA, Knight, M, Sharpe, P. The CAPS Study: incidence, management and outcomes of cardiac arrest in pregnancy in the UK: a prospective, descriptive study. BJOG. 2017;124(9):1374–81.Google Scholar