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  • Cited by 1
  • Print publication year: 2010
  • Online publication date: May 2011

9 - Bringing a Population Health Perspective to Early Biodevelopment: An Emerging Approach

Summary

This chapter describes the rationale for population-based monitoring of early child development (ECD); outlines our achievements to date in producing such ECD data for a large population (the kindergarten children of British Columbia, Canada); and shows how this work can support biodevelopmental research regarding the extent to which social gradients in brain and biological development are explained by experience “getting under the skin.”

GRADIENTS IN EARLY CHILD DEVELOPMENT

Inequalities in child development emerge in a systematic fashion over the first five years of life, according to well-recognized factors: family income, parental education, parenting style, neighborhood safety and cohesion, neighborhood socioeconomic status, and access to quality childcare and other developmental opportunities. Three broad domains of ECD are of special relevance: physical, social/emotional, and language/cognitive. By age 5, as one goes from the families with the lowest to highest incomes, least to most parental education, and least to most nurturing and interactive parenting style, the average quality of early child experiences gradually increases and produces a gradient in child development (Hertzman et al., 2002). For example, data from the National Longitudinal Survey of Children and Youth from the late 1990s (Willms, 2002) showed a gradient in the risk of receptive language delay, increasing gradually from the children in the highest income decile of Canadian families (5.2 percent delayed) to the poorest decile (approximately 26 percent delayed).

References
Barker, D. J. (1995). The Wellcome Foundation Lecture 1994. The fetal origins of adult disease. Proceedings of the Royal Society of London: B Biological Science, 262, 37–43.
Boyle, M., & Lipman, E. (2002). Do places matter? Socioeconomic disadvantage and behavioural problems of children in Canada. Journal of Consulting and Clinical Psychology, 70(2), 378–89.
Brooks-Gunn, J., Duncan, G., Klebanov, P., & Sealand, N. (1993). Do neighborhoods influence child and adolescent development? American Journal of Sociology, 99(2), 353–95.
Burton, L., & Jarrett, R. (2000). In the mix, yet on the margins: The place of families in urban neighborhood and child development research. Journal of Marriage and the Family, 62, 1114–35.
Comb, M., & Goodman, H. M. (1990). CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2. Nucleic Acids Res, 18, 3975–82.
Curtis, Lori J., Dooley, M., & Phipps, S. (2004). Child well-being and neighborhood quality: Evidence from the Canadian National Longitudinal Survey of Children and Youth. Social Science and Medicine, 58, 1917–27.
Gunnar, M. R., Morison, S. J., Chisholm, K., & Schuder, M. (2001). Salivary cortisols in children adopted from Romanian orphanages. Development and Psychopathology. 13, 611–28.
Gunnar, M. R., & Nelson, C. A. (1994). Event-related potentials in year-old infants: Relations with emotionality and cortisol. Child Development, 65, 80–94.
Hart, B., & Risley, T. R. (1995). Meaningful differences in the everyday experience of young American children. Baltimore: Paul H Brooks Publishing Co.
Hertzman, C. (2000). The biological embedding of early experience and its effects on health in adulthood. Annals of the New York Academy of Sciences, 896, 85–95.
Hertzman, C., McLean, S., Kohen, D., Dunn, J., & Evans, T. (2002). Early Development in Vancouver: Report of the Community Asset Mapping Project (CAMP). Human Early Learning Partnership [cited. Available from http://www.earlylearning.ubc.ca/vancouvermaps.pdf.]
Hertzman, C., Power, C., Matthews, S., & Manor, O. (2001). Using an interactive framework of society and life course to explain self-rated health in early adulthood. Social Science and Medicine, 53, 1575–85.
Janus, M., & Offord, D. R. (2000). Reporting on readiness to learn in Canada ISUMA. Canadian Journal of Policy Research, 1, 71–5.
Jefferis, B., Power, C., & Hertzman, C. (2002). Birth weight, childhood socioeconomic environment, and cognitive development in the 1958 birth cohort. British Medical Journal, 325, 305–11.
Jencks, C., & Mayer, S. (1990). The social consequences of growing up in a poor neighborhood. In Lynn, L. & McGeary, M. (Eds.), Inner-city poverty in the United States. Washington, DC: National Academy Press.
Jenuwein, T., & Allis, C. D. (2001). Translating the histone code. Science, 293, 1074–80.
Jones, P. L. et al. (1998). Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat Genet, 19, 187–91.
Keating, D. P. (2007). Formative evaluation of the Early Development Instrument: Progress and prospects. Early Education and Development, 18(3), 561–70.
Keating, D. P. (2009). Social interactions in human development: Pathways to health and capabilities. In Hall, P. & Lamont, M. (Eds.), Successful societies: Institutions, cultural repertoires, and population health. New York: Cambridge University Press.
Keating, P., & Hertzman, C. (1999). Developmental health and the wealth of nations: Social, biological, and educational dynamics. New York: Guildford Press.
Kershaw, P., Irwin, L., Trafford, K., & Hertzman, C. (2006). British Columbia Atlas of Child Development. Vancouver: UBC Press.
Kohen, D., Brooks-Gunn, J., Leventhal, T., & Hertzman, C. (2002). Neighborhood income and physical and social disorder in Canada: Associations with young children's competencies. Child Development, 73(6), 1844–60.
Kristenson, M., Orth-Goméer, K., Kucinskienë, Z., Bergdahl, B., Calkauskas, H., Balinkyniene, I., et al. (1998). Attenuated cortisol response to a standardized stress test in Lithuanian versus Swedish men: The LiVicordia study. International Journal of Behavioral Medicine, 5(1), 17–30.
Li, L., Power, C., Kelly, S., & Kirschbaum, C., & Hertzman, C. (2007). Lifetime socioeconomic position and cortisol secretion patterns in mid-life. Psychoneuroendocrinology, 32(7), 824–33.
Lupien, S. J., King, S., Meaney, M. J., & McEwen, B. S. (2001). Can poverty get under your skin? Basal cortisol levels and cognitive function in children from low and high socioeconomic status. Development and Psychopathology, 13, 653–76.
McEwen, B. (1998). Protective and damaging effects of stress mediators. New England Journal of Medicine, 338, 171–9.
Meaney, M. J. (2001). Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. Annual Review of Neuroscience, 24, 1161–92.
Nan, X., Campoy, F. J., & Bird, A. (1997). MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell, 88, 471–81.
,National Research Council Institute of Medicine. (2000). From neurons to neighborhoods: The science of early childhood development. Washington, DC: National Academy Press.
,Organisation for Economic Cooperation and Development. (2006). Starting strong II. Early childhood education and care. Paris, France. ISBN 92–64–03545–1.
Power, C., Li, L., Atherton, K., & Hertzman, C. (2010). Psychological health throughout life and adult cortisol patterns at age 45y. Psychoneuroenocrinology, doi:10.1016/j.psyneuen.2010.06.010
Power, C., Li, L., & Hertzman, C. (2006). Patterns of growth from birth to adulthood, adiposity and cortisol in mid-adulthood. Journal of Clinical Endocrinology & Metabolism, 91, 4264–70.
Power, C., Li, L., & Hertzman, C. (2008). Cognitive development and cortisol patterns in mid-life: Findings from a British birth cohort. Psychoneuroendorcinology, 33(4), 530–9.
Ramey, C. T., & Ramey, S. L. (2005). Early learning and school readiness: Can early intervention make a difference?Washington, DC: Georgetown University Center on Health and Education.
Razin, A., & Riggs, A. D. (1980). DNA methylation and gene function. Science, 210, 604–10.
Razin, A., & Szyf, M. (1984). DNA methylation patterns. Formation and function. Biochim Biophys Acta, 782, 331–42.
Sapolsky, R. M. (1992). Stress, the aging brain, and the mechanisms of neuron death. Cambridge, MA: MIT Press.
Schweinhart, L. J. (2004). The High/Scope Perry Preschool Study through Age 40. Summary, conclusions, and frequently asked questions. Ypsilanti, MI: High/Scope Educational Research Foundation.
Strahl, B. D., & Allis, C. D. (2000).The language of covalent histone modifications. Nature, 403, 41–5.
Szyf, M. (2003a). DNA methylation enzymology. In Encyclopedia of the human genome. New York: Macmillan Publishers, Nature Publishing Group.
Szyf, M. (2003b). Targeting DNA methylation in cancer. Ageing Res Rev, 2, 299–328.
Szyf, M. (2009). Early life, the epigenome, and human health. Acta Paediatrica, 98, 1082–4.
Turley, R., & Lopez, T. (2003). When do neighborhoods matter? The role of race and neighborhood peers. Social Science Research, 32(1), 61–79.
Weaver, I. C. G., Cervoni, F. A., Champagne, F. A., Alessio, A. C. D., Sharma, S., Seckl, J. R., Dymov, S., Szyf, M., & Meaney, M. J. (2004). Epigenetic programming by maternal behavior. Nature Neuroscience, 7, 847–54.
Weaver, I. C., Meaney, M. J., & Szyf, M. (2006). Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood. Proceedings of the National Academy of Sciences, 103, 3480–5.
Willms, J. D. (Ed.). (2002). Vulnerable children. Edmonton, AB: University of Alberta Press.