These provisions and arrangements having been made we set sail and departed from the port of Callao, which is in 12°25′, on the 11th of October 1579, at 4 o'clock in the afternoon, in the name of the most holy Trinity, three persons and one only God, Father, Son, and Holy Ghost. That same night we came to off the island of the port, which is two leagues to the west of Callao. We anchored there because it was necessary to make the Capitana secure, and to finish putting her in order. For there had been neglect in stowing her ballast, and she could not carry her sails. That night the crews had no sleep, because all were at work, some bringing ballast from the island, others finishing the setting up of shrouds and reeving of running rigging, which there was no time to complete in port. On Monday, being the morning of the 12th, with a fair northerly breeze, we left the island, and shaped a southerly course, passing between the island and the point of the port, which has very seldom been done. Beginning by standing out to sea, we then tacked and stood in towards the land. On this tack we sailed under a Morro called Solar, in the valley of Surco, two leagues from the island, and three from Callao.

On Tuesday the thirteenth of October, when we began to stand out to sea, we presently found that the bows of the Capilana were opening in many parts, owing to several seams not having been caulked. The haste in despatching the expedition did not give time for the overseers to see to everything.