Skip to main content Accessibility help
  • Print publication year: 2010
  • Online publication date: August 2011

Chapter 1 - Conduction studies in multiple sclerosis

from Section 1 - Basic mechanisms


1. ChiappaK H, RopperA H.Evoked potentials in clinical medicine (first of two parts). N Engl J Med 1982;306:1140–50
2. MayrN, BaumgartnerC, ZeitlhoferJ, DeeckeL.The sensitivity of transcranial cortical magnetic stimulation in detecting pyramidal tract lesions in clinically definite multiple sclerosis. Neurology 1991;41:566–9
3. RavnborgM, LiguoriR, ChristiansenP, LarssonH, SorensenP S.The diagnostic reliability of magnetically evoked motor potentials in multiple sclerosis. Neurology 1992;42:1296–301
4. BeerS, RöslerK M, HessC W.Diagnostic value of paraclinical tests in multiple sclerosis: relative sensitivities and specificities for reclassification according to the Poser Committee criteria. J Neurol Neurosurg Psychiatry 1995;59:152–9
5. PoserC M, PatyD W, ScheinbergL, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983;13:227–31
6. McDonaldW I, CompstonA, EdanG, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol 2001;50:121–7
7. SimonJ H, JacobsL D, CampionM, et al. Magnetic resonance studies of intramuscular interferon beta-1a for relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group. Ann Neurol 1998;43:79–87
8. KapposL, MoeriD, RadueE W, et al. Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and changes in disability or impairment in multiple sclerosis: a meta-analysis. Gadolinium MRI Meta-analysis Group. Lancet 1999;353:964–9
9. FacchettiD, MaiR, MicheliA, et al. Motor evoked potentials and disability in secondary progressive multiple sclerosis. Can J Neurol Sci 1997;24:332–7
10. O'ConnorP, MarchettiP, LeeL, PereraM.Evoked potential abnormality scores are a useful measure of disease burden in relapsing–remitting multiple sclerosis. Ann Neurol 1998;44:404–7
11. FuhrP, Borggrefe-ChappuisA, SchindlerC, KapposL.Visual and motor evoked potentials in the course of multiple sclerosis. Brain 2001;124:2162–8
12. BrusaA, JonesS J, PlantG T. 2001; Long-term remyelination after optic neuritis: a 2-year visual evoked potential and psychophysical serial study. Brain 2001;124:468–79
13. La MantiaL, RitiF, MilaneseC, et al. Serial evoked potentials in multiple sclerosis bouts: relation to steroid treatment. Ital J Neurol Sci 1994;15:333–40
14. HessC W, MillsK R, MurrayN M, SchrieferT N.Magnetic brain stimulation: central motor conduction studies in multiple sclerosis. Ann Neurol 1987;22:744–52
15. SmithK J, McDonaldW I.The pathophysiology of multiple sclerosis: the mechanisms underlying the production of symptoms and the natural history of the disease. Phil Trans R Soc Lond B 1999;354:1649–73
16. HummA M, MagistrisM R, TruffertA, HessC W, RöslerK M.Central motor conduction differs between acute relapsing–remitting and chronic progressive multiple sclerosis. Clin Neurophysiol 2003;114:2196–203
17. HummA M, Z'GraggenW J, BuhlerR, MagistrisM R, RöslerK M.Quantification of central motor conduction deficits in multiple sclerosis patients before and after treatment of acute exacerbation by methylprednisolone. J Neurol Neurosurg Psychiatry 2006;77:345–50
18. HummA M, BeerS, KoolJ, et al. Quantification of Uhthoff's phenomenon in multiple sclerosis: a magnetic stimulation study. Clin Neurophysiol 2004;115:2493–501
19. PerssonH E, SachsC.Visual evoked potentials elicited by pattern reversal during provoked visual impairment in multiple sclerosis. Brain 1981;104:369–82
20. StöhrM.Somatosensorisch evozierte Potentiale SEP. In: MaurerK, LowitzschK, StöhrM, eds. Evozierte Potentiale AEP – VEP – SEP. Stuttgart: Ferdinand Enke Verlag, 1990;183–4
21. MagistrisM R, RöslerK M, TruffertA, MyersJ P.Transcranial stimulation excites virtually all motor neurons supplying the target muscle: a demonstration and a method improving the study of motor evoked potentials. Brain 1998;121(3):437–50
22. RöslerK M.Transcranial magnetic brain stimulation: a tool to investigate central motor pathways. News Physiol Sci 2001;16:297–302
23. ChenR, CrosD, CurraA, et al. The clinical diagnostic utility of transcranial magnetic stimulation: report of an IFCN committee. Clin Neurophysiol 2008;119:504–32
24. AmassianV E, CraccoR Q, MaccabeeP J.Focal stimulation of human cerebral cortex with the magnetic coil: a comparison with electrical stimulation. Electroencephalogr Clin Neurophysiol 1989;74:401–16
25. KiersL, CrosD, ChiappaK H, FangJ.Variability of motor potentials evoked by transcranial magnetic stimulation. Electroencephalogr Clin Neurophysiol 1993;89:415–23
26. RöslerK M, PetrowE, MathisJ, et al. Effect of discharge desynchronization on the size of motor evoked potentials: an analysis. Clin Neurophysiol 2002;113:1680–7
27. RöslerK M, RothD M, MagistrisM R.Trial-to-trial size variability of motor-evoked potentials: a study using the triple stimulation technique. Exp Brain Res 2008;187:51–9
28. BrittonT C, MeyerB U, BeneckeR.Variability of cortically evoked motor responses in multiple sclerosis. Electroencephalogr Clin Neurophysiol 1991;81:186–94
29. ZentnerJ, MeyerB.Diagnostic significance of MEP elicited by electrical and magnetoelectric stimulation in acute/subacute supratentorial lesions. Electromyogr Clin Neurophysiol 1998;38:33–40
30. MagistrisM R, RöslerK M, TruffertA, LandisT, HessC W.A clinical study of motor evoked potentials using a triple stimulation technique. Brain 1999;122(2):265–79
31. BühlerR, MagistrisM R, TruffertA, HessC W, RöslerK M.The triple stimulation technique to study central motor conduction to the lower limbs. Clin Neurophysiol 2001;112:938–49
32. JonesS J, BrusaA.Neurophysiological markers of relapse, remission and long-term recovery processes in MS. Electroencephalogr Clin Neurophysiol Suppl 1999;50:584–90
33. SmithK J.Conduction properties of central demyelinated and remyelinated axons, and their relation to symptom production in demyelinating disorders. Eye 1994;8(2):224–37
34. AnderssonP B, GoodkinD E.Glucocorticosteroid therapy for multiple sclerosis: a critical review. J Neurol Sci 1998;160:16–25
35. KandlerR H, JarrattJ A, Davies-JonesG A, et al. The role of magnetic stimulation as a quantifier of motor disability in patients with multiple sclerosis. J Neurol Sci 1991;106:31–4
36. SalleJ Y, HugonJ, TabaraudF, et al. Improvement in motor evoked potentials and clinical course post-steroid therapy in multiple sclerosis. J Neurol Sci 1992;108:184–8
37. FierroB, SalemiG, BrighinaF, et al. A transcranial magnetic stimulation study evaluating methylprednisolone treatment in multiple sclerosis. Acta Neurol Scand 2002;105:152–7
38. SchaufC L, DavisF A.Impulse conduction in multiple sclerosis: a theoretical basis for modification by temperature and pharmacological agents. J Neurol Neurosurg Psychiatry 1974;37:152–61
39. FeltsP A, BakerT A, SmithK J.Conduction in segmentally demyelinated mammalian central axons. J Neurosci 1997;17:7267–77