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MicroRNAs
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Book description

MicroRNAs (miRNAs) are RNA molecules, conserved by evolution, that regulate gene expressions and their discovery has revolutionised both basic biomedical research and drug discovery. Expression levels of miRNAs have been found to vary between tissues and with developmental stages and hence evaluation of the global expression of miRNAs potentially provides opportunities to identify regulatory points for many different biological processes. This wide-ranging reference work, written by leading experts from both academia and industry, will be an invaluable resource for all those wishing to use miRNA techniques in their own research, from graduate students, post-docs and researchers in academia to those working in R&D in biotechnology and pharmaceutical companies who need to understand this emerging technology. From the discovery of miRNAs and their functions to their detection and role in disease biology, this volume uniquely integrates the basic science with industry application towards drug validation, diagnostic and therapeutic development.

Reviews

'… comprehensive and detailed … compiled logically … informative and easy to read.'

Source: Microbiology Today

'… a useful reference guide for those interested in miRNA …'

Source: Immunology News

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Contents


Page 1 of 2


  • 1 - The microRNAs of C. elegans
    pp 7-21
    • By Ines Alvarez-Garcia, The Wellcome Trust/Cancer Research UK Gurdon Institute and Department of Biochemistry, The Henry Wellcome Building of Cancer and Developmental Biology, University of Cambridge, Tennis Court Road Cambridge CB2 1QN, United Kingdom, Eric A. Miska, The Wellcome Trust/Cancer Research UK Gurdon Institute and Department of Biochemistry, The Henry Wellcome Building of Cancer and Developmental Biology, University of Cambridge, Tennis Court Road Cambridge CB2 1QN, United Kingdom
  • 5 - Identification of miRNAs in the plant Oryza sativa
    pp 70-82
    • By Hui Zhou, Biotechnology Research Center Key Laboratory of Gene Engineering of the Ministry of Education Zhongshan University Guangzhou, 510275 People's Republic of China, Yue-Qin Chen, Biotechnology Research Center Key Laboratory of Gene Engineering of the Ministry of Education Zhongshan University Guangzhou, 510275 People's Republic of China, Yu-Chun Luo, Biotechnology Research Center Key Laboratory of Gene Engineering of the Ministry of Education Zhongshan University Guangzhou, 510275 People's Republic of China, Jia-Fu Wang, Biotechnology Research Center Key Laboratory of Gene Engineering of the Ministry of Education Zhongshan University Guangzhou, 510275 People's Republic of China, Liang-Hu Qu, Biotechnology Research Center Key Laboratory of Gene Engineering of the Ministry of Education Zhongshan University Guangzhou, 510275 People's Republic of China
  • 7 - In situ analysis of microRNA expression during vertebrate development
    pp 102-114
    • By Diana K. Darnell, Department of Cell Biology and Anatomy University of Arizona PO Box 245044 Life Sciences North 462 1501 N. Campbell Avenue Tucson, AZ 85724-5044 USA, Stacey Stanislaw, Department of Cell Biology and Anatomy University of Arizona PO Box 245044 Life Sciences North 462 1501 N. Campbell Avenue Tucson, AZ 85724-5044 USA, Simran Kaur, Department of Cell Biology and Anatomy University of Arizona PO Box 245044 Life Sciences North 462 1501 N. Campbell Avenue Tucson, AZ 85724-5044 USA, Tatiana A. Yatskievych, Department of Cell Biology and Anatomy University of Arizona PO Box 245044 Life Sciences North 462 1501 N. Campbell Avenue Tucson, AZ 85724-5044 USA, Sean Davey, Department of Cell Biology and Anatomy University of Arizona PO Box 245044 Life Sciences North 462 1501 N. Campbell Avenue Tucson, AZ 85724-5044 USA, Jay H. Konieczka, Department of Cell Biology and Anatomy University of Arizona PO Box 245044 Life Sciences North 462 1501 N. Campbell Avenue Tucson, AZ 85724-5044 USA, Parker B. Antin, Department of Cell Biology and Anatomy University of Arizona PO Box 245044 Life Sciences North 462 1501 N. Campbell Avenue Tucson, AZ 85724-5044 USA

Page 1 of 2


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