The chapter focuses on Manuel's travels in Western Europe (1399–1402). It discusses at length the political aspects of his presence at the English, French and Italian courts, offering new interpretations of the events. Other topics are Manuel's personal experiences in Europe, and his letters and interactions with prominent European figures of the time. Manuel's use of relics as diplomatic gifts receives further attention. The Procession of the Holy Spirit, a theological treatise penned by the emperor at time, is analysed at length with regard to its literary features, connections to the other treatises of time and Manuel's theological thought. Other shorter writings from the same period are also investigated. The chapter ends with the defeat of the Ottomans by Tamerlane and Manuel's subsequent return to Constantinople.