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2.48 - Imipramine

from Tricyclic Antidepressants

Published online by Cambridge University Press:  19 October 2021

Michael Cummings
Affiliation:
University of California, Los Angeles
Stephen Stahl
Affiliation:
University of California, San Diego
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Summary

Typical or first-generation antipsychotic (FGA)

Type
Chapter
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Publisher: Cambridge University Press
Print publication year: 2021

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References

Deupree, J. D., Montgomery, M. D., Bylund, D. B. (2007). Pharmacological properties of the active metabolites of the antidepressants desipramine and citalopram. Eur J Pharmacol, 576, 5560.CrossRefGoogle ScholarPubMed
Lopez-Munoz, F., Alamo, C. (2009). Monoaminergic neurotransmission: the history of the discovery of antidepressants from 1950s until today. Curr Pharm Des, 15, 15631586.Google Scholar
Perry, P. J., Zeilmann, C., Arndt, S. (1994). Tricyclic antidepressant concentrations in plasma: an estimate of their sensitivity and specificity as a predictor of response. J Clin Psychopharmacol, 14, 230240.CrossRefGoogle ScholarPubMed
Rief, W., Nestoriuc, Y., von Lilienfeld-Toal, A., et al. (2009). Differences in adverse effect reporting in placebo groups in SSRI and tricyclic antidepressant trials: a systematic review and meta-analysis. Drug Saf, 32, 10411056.CrossRefGoogle ScholarPubMed
Rodriguez de la Torre, B., Dreher, J., Malevany, I., et al. (2001). Serum levels and cardiovascular effects of tricyclic antidepressants and selective serotonin reuptake inhibitors in depressed patients. Ther Drug Monit, 23, 435440.Google Scholar
Hicks, J. K., Sangkuhl, K., Swen, J. J., et al. (2017). Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update. Clin Pharmacol Ther, 102, 3744.CrossRefGoogle ScholarPubMed
Nagy, A., Johansson, R. (1975). Plasma levels of imipramine and desipramine in man after different routes of administration. Naunyn Schmiedebergs Arch Pharmacol, 290, 145160.Google Scholar
Lieberman, J. A., Cooper, T. B., Suckow, R. F., et al. (1985). Tricyclic antidepressant and metabolite levels in chronic renal failure. Clin Pharmacol Ther, 37, 301307.CrossRefGoogle ScholarPubMed
Sallee, F. R., Pollock, B. G. (1990). Clinical pharmacokinetics of imipramine and desipramine. Clin Pharmacokinet, 18, 346364.CrossRefGoogle ScholarPubMed
Rasmussen, B. B., Nielsen, T. L., Brøsen, K. (1998). Fluvoxamine inhibits the CYP2C19-catalysed metabolism of proguanil in vitro. Eur J Clin Pharmacol, 54, 735740. doi: 710.1007/s002280050544CrossRefGoogle ScholarPubMed
Undurraga, J., Baldessarini, R. J. (2017). Direct comparison of tricyclic and serotonin-reuptake inhibitor antidepressants in randomized head-to-head trials in acute major depression: systematic review and meta-analysis. J Psychopharmacol, 31, 11841189.CrossRefGoogle ScholarPubMed
Bighelli, I., Castellazzi, M., Cipriani, A., et al. (2018). Antidepressants versus placebo for panic disorder in adults. Cochrane Database Syst Rev, 4, CD010676.Google ScholarPubMed

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  • Imipramine
  • Edited by Michael Cummings, University of California, Los Angeles, Stephen Stahl, University of California, San Diego
  • Book: Management of Complex Treatment-resistant Psychotic Disorders
  • Online publication: 19 October 2021
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  • Imipramine
  • Edited by Michael Cummings, University of California, Los Angeles, Stephen Stahl, University of California, San Diego
  • Book: Management of Complex Treatment-resistant Psychotic Disorders
  • Online publication: 19 October 2021
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Imipramine
  • Edited by Michael Cummings, University of California, Los Angeles, Stephen Stahl, University of California, San Diego
  • Book: Management of Complex Treatment-resistant Psychotic Disorders
  • Online publication: 19 October 2021
Available formats
×