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2.09 - Clozapine

from Second-Generation (Atypical) Antipsychotics

Published online by Cambridge University Press:  19 October 2021

Edited by
Michael Cummings  and
Stephen Stahl
Michael Cummings
Affiliation:
University of California, Los Angeles
Stephen Stahl
Affiliation:
University of California, San Diego
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Summary

Typical or first-generation antipsychotic (FGA)

Type
Chapter
Information
Management of Complex Treatment-resistant Psychotic Disorders , pp. 137 - 144
Publisher: Cambridge University Press
Print publication year: 2021

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References

Jazz Pharmaceuticals Inc. Fazaclo Package Insert. Palo Alto, California.Google Scholar
HLS Therapeutics (U.S.) Inc. (2019). Clozaril Package Insert. Rosemont, Pennsylvania.Google Scholar
Meyer, J. M. (2019). The Clozapine Handbook: Stahl’s Handbooks. New York: Cambridge University Press.CrossRefGoogle Scholar
TruPharma LLC. (2020). Versacloz Package Insert. Tampa, Florida.Google Scholar
Remington, G., Agid, O., Foussias, G., et al. (2013). Clozapine and therapeutic drug monitoring: is there sufficient evidence for an upper threshold? Psychopharmacology (Berl), 225, 505–518.CrossRefGoogle ScholarPubMed
California Department of State Hospitals. (2019). DSH Psychotropic Medication Policy: Clozapine Protocol. Sacramento, California.Google Scholar
De Berardis, D., Rapini, G., Olivieri, L., et al. (2018). Safety of antipsychotics for the treatment of schizophrenia: a focus on the adverse effects of clozapine. Ther Adv Drug Saf, 9, 237–256.CrossRefGoogle ScholarPubMed
Maguire, G. A. (2002). Comprehensive understanding of schizophrenia and its treatment. Am J Health Syst Pharm, 59, S4–11.CrossRefGoogle ScholarPubMed
Solmi, M., Murru, A., Pacchiarotti, I., et al. (2017). Safety, tolerability, and risks associated with first- and second-generation antipsychotics: a state-of-the-art clinical review. Ther Clin Risk Manag, 13, 757–777.CrossRefGoogle ScholarPubMed
Jin, H., Meyer, J. M., Jeste, D. V. (2002). Phenomenology of and risk factors for new-onset diabetes mellitus and diabetic ketoacidosis associated with atypical antipsychotics: an analysis of 45 published cases. Ann Clin Psychiatry, 14, 59–64.CrossRefGoogle ScholarPubMed
American Diabetes Association, American Psychiatric Association, American Association of Clinical Endocrinologists, et al. (2004). Consensus development conference on antipsychotic drugs and obesity and diabetes. Obes Res, 12, 362–368.CrossRefGoogle Scholar
Howland, R. H. (2010). Potential adverse effects of discontinuing psychotropic drugs. J Psychosoc Nurs Ment Health Serv, 48, 11–14.Google ScholarPubMed
Lally, J., Malik, S., Krivoy, A., et al. (2017). The use of granulocyte colony-stimulating factor in clozapine rechallenge: a systematic review. J Clin Psychopharmacol, 37, 600–604.CrossRefGoogle ScholarPubMed
Lally, J., Malik, S., Whiskey, E., et al. (2017). Clozapine-associated agranulocytosis treatment with granulocyte colony-stimulating factor/granulocyte-macrophage colony-stimulating factor: a systematic review. J Clin Psychopharmacol, 37, 441–446.CrossRefGoogle ScholarPubMed
Andres, E., Zimmer, J., Mecili, M., et al. (2011). Clinical presentation and management of drug-induced agranulocytosis. Expert Rev Hematol, 4, 143–151.CrossRefGoogle ScholarPubMed

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  • Clozapine
  • Edited by Michael Cummings, University of California, Los Angeles, Stephen Stahl, University of California, San Diego
  • Book: Management of Complex Treatment-resistant Psychotic Disorders
  • Online publication: 19 October 2021
Available formats
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  • Clozapine
  • Edited by Michael Cummings, University of California, Los Angeles, Stephen Stahl, University of California, San Diego
  • Book: Management of Complex Treatment-resistant Psychotic Disorders
  • Online publication: 19 October 2021
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Clozapine
  • Edited by Michael Cummings, University of California, Los Angeles, Stephen Stahl, University of California, San Diego
  • Book: Management of Complex Treatment-resistant Psychotic Disorders
  • Online publication: 19 October 2021
Available formats
×