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Chapter 16 - Mitochondrial Transfer Technology for Improving Older Eggs

from Section 3 - Supplements to Improve Oocytes

Published online by Cambridge University Press:  04 January 2019

Gabor Kovacs
Affiliation:
Monash University, Victoria
Anthony Rutherford
Affiliation:
University of Leeds
David K. Gardner
Affiliation:
University of Melbourne
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Publisher: Cambridge University Press
Print publication year: 2019

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References

Cavelier, L, Johannisson, A, Gyllensten, U. Analysis of mtDNA copy number and composition of single mitochondrial particles using flow cytometry and PCR. Exp. Cell Res 2000; 259, 7985.Google Scholar
May‐Panloup, P, Chrétien, M‐F, Savagner, F et al. Increased sperm mitochondrial DNA content in male infertility. Hum Reprod 2003; 18 (3): 550556. doi:10.1093/humrep/deg096Google Scholar
Tian, et al. Association of DNA Methylation and Mitochondrial DNA Copy Number with Human Semen Quality. Biol Reprod. 2014 September 10.Google Scholar
Van Blerkom, J. Mitochondrial function in the human oocyte and embryo and their role in developmental competence. Mitochondrion. 2011 September;11(5):797813. doi:10.1016/j.mito.2010.09.012. Epub 2010 October 7Google Scholar
Reynier, P, May‐Panloup, P, Chretien, MF et al. Mitochondrial DNA content affects the fertilizability of human oocytes. Mol. Hum. Reprod. 2001;7, 425429.Google Scholar
Sato, Miyuki, Sato, Ken. Maternal inheritance of mitochondrial DNA by diverse mechanisms to eliminate paternal mitochondrial DNA, Biochimica et Biophysica Acta (BBA) – Molecular Cell Research 2013August; 1833:8, 19791984.Google Scholar
Schwartz, M, Vissing, J. Paternal inheritance of mitochondrial DNA. N Engl J Med. 2002;347: 576580.Google Scholar
St John, J, Sakkas, D, Dimitriadi, K et al. Failure of elimination of paternal mitochondrial DNA in abnormal embryos. Lancet 2000;355:200.Google Scholar
Houshmand, M, Holme, E, Hanson, C, Wennerholm, UB, Hamberger, L. Is paternal mitochondrial DNA transferred to the offspring following intracytoplasmic sperm injection? J Assist Reprod Genet 1997;14:223227.Google Scholar
Canadian Assisted Reproductive Technologies Register (CARTR Plus). 62nd Annual Meeting – Toronto. September 22–24, 2016. https://cfas.ca/wp-content/uploads/2015/08/BORN-CFAS-CARTR-Plus-presentation-Oct-2016-for-website-1. www.sartcorsonline.com/rptCSR_PublicMultYear.aspx?reportingYear=2014Google Scholar
Hansen, KR, Knowlton, NS, Thyer, AC A new model of reproductive aging: the decline in ovarian non-growing follicle number from birth to menopause. Human Reprod. 2008; 23: 699708.Google Scholar
Tsutsumi, M, Fujiwara, R, Nishizawa, H et al. Age-related decrease of meiotic cohesins in human oocytes. PLoS ONE 2014;9 e96710.Google Scholar
Bentov, Y, Yavorska, T, Esfandiari, N, Jurisicova, A, Casper, RF. The contribution of mitochondrial function to reproductive aging, Journal of Assisted Reproduction and Genetics 2011;28, 773783.CrossRefGoogle ScholarPubMed
Kristensen, SG1, Pors, SE1, Andersen, CY1. Improving oocyte quality by transfer of autologous mitochondria from fully grown oocytes. Hum Reprod. 2017; March 2:1–8. doi:10.1093/humrep/dex043. [Epub ahead of print]Google Scholar
Babayev, E, Seli, E. Oocyte mitochondrial function and reproduction. Curr Opin Obstet Gynecol. 2015 Jun;27(3): 175-181.Google Scholar
Agarwal, A, Durairajanayagam, D, du Plessis, SS. Utility of antioxidants during assisted reproductive techniques: an evidence based review. Reprod Biol Endocrinol. 2014 November 24;12:112.Google Scholar
Muggleton-Harris, A, Whittingham, DG, Wilson, L. Cytoplasmic control of pre-implantation development in in vitro in the mouse. Nature 1982; 299:460462.Google Scholar
Levron, J1, Willadsen, S, Bertoli, M, Cohen, J. The development of mouse zygotes after fusion with synchronous and asynchronous cytoplasm. Hum Reprod. 1996 June;11(6):12871292.Google Scholar
Cohen, J, Scott, R, Alikani, M et al. Ooplasmic transfer in mature human oocytes. Mol Hum Reprod. 1998 March;4(3):269280.Google Scholar
Sharpley, MS, Marciniak, C, Eckel-Mahan, K et al. Heteroplasmy of mouse mtDNA is genetically unstable and results in altered behavior and cognition. Cell. 2012 October 12; 151(2):333343.CrossRefGoogle ScholarPubMed
Craven, L, Tuppen, HA, Greggains, GD et al. Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease. Nature. 2010 May 6; 465(7294):8285.CrossRefGoogle ScholarPubMed
Tachibana, M, Amato, P, Sparman, M et al. Towards germline gene therapy of inherited mitochondrial diseases. Nature. 2013 January 31; 493(7434):627631.Google Scholar
Brenner, CA, Barritt, JA, Willadsen, S, Cohen, J. Mitochondrial DNA heteroplasmy after human ooplasmic transplantation, Fertility and Sterility. 2000;74(3), 573578.CrossRefGoogle ScholarPubMed
Amato, P, Tachibana, M, Sparman, M, Mitalipov, S. Three-Parent IVF: Gene replacement for the prevention of inherited mitochondrial diseases. Fertility and Sterility. 2014;101(1):3135. doi:10.1016/j.fertnstert.2013.11.030.Google Scholar
Tachibana, M, Amato, P, Sparman, M et al. Towards germline gene therapy of inherited mitochondrial diseases. Nature. 2013 January 31; 493(7434):627631.Google Scholar
Brenner, CA, Kubisch, HM, Pierce, KE. The role of the mitochondrial genome in assisted reproductive technologies and embryonic stem cell-based therapeutic cloning. Reproduction, Fertility and Development. 2005;16(7), 743751.Google Scholar
Nakada, K, Hayashi, JI. Transmitochondrial mice as models for mitochondrial DNA-based diseases, Experimental Animals. 2011;60, 421431.Google Scholar
Johnson, J, Canning, J, Kaneko, T, Pru, JK, Tilly, JL. Germline stem cells and follicular renewal in the postnatal mammalian ovary. Nature. 2004 March 11; 428(6979), 145150.Google Scholar
Zou, K, Yuan, Z, Yang, Z et al. Production of offspring from a germline stem cell line derived from neonatal ovaries. Nat Cell Biol. 2009;11, 631636.Google Scholar
Cagnone, GL1,2, Tsai, TS1,2, Makanji, Y1,2. Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency. Sci Rep. 2016 March 18;6, 23229. doi:10.1038/srep23229.Google Scholar
Ravichandran, K, McCaffrey, C, Grifo, J et al. Mitochondrial DNA quantification as a tool for embryo viability assessment: retrospective analysis of data from single euploid blastocyst transfers. Hum Reprod. 2017 April 6:1–11. doi:10.1093/humrep/dex070. [Epub ahead of print]Google Scholar
Fragouli, E, Spath, K, Alfarawati, S et al. Altered levels of mitochondrial DNA are associated with female age, aneuploidy, and provide an independent measure of embryonic implantation potential. PLoS Genet 2015;11:e1005241.Google Scholar

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