Skip to main content Accessibility help
×
Home
  • Print publication year: 2016
  • Online publication date: May 2016

Chapter 2 - Overview of frontotemporal dementia and its relationship to other neurodegenerative disorders

from Section 1 - Introduction to and brief history of FTD

Related content

Powered by UNSILO
1. Pick, A. Über die Beziehungen der senilen Hirnatrophie zur Aphasie. Prag Med Wochenschr 1892;17:165–7.
2. Pick, A. Zur symptomatologie der linksseitigen Schlafenlappenatrophie. Monatsschr Psychiatr Neurol 1904;16:378–88.
3. Snowden, J, Goulding, P, Neary, D. Semantic dementia: a form of circumscribed cerebral atrophy. Behav Neurol 1989;2:167–82.
4. Hodges, JR, Patterson, K, Oxbury, S, Funnell, E. Semantic dementia. Progressive fluent aphasia with temporal lobe atrophy. Brain 1992;115(Pt 6):1783–806.
5. Brun, A. Frontal lobe degeneration of non-Alzheimer type. I. Neuropathology. Arch Gerontol Geriatr 1987;6(3):193208.
6. Neary, D, Snowden, JS, Northen, B, Goulding, P. Dementia of frontal lobe type. J Neurol Neurosurg Psychiatry 1988;51(3):353–61.
7. Neary, D, Snowden, JS, Gustafson, L, Passant, U, Stuss, D, Black, S, et al. Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 1998;51(6):1546–54.
8. Mesulam, MM. Primary progressive aphasia – differentiation from Alzheimer's disease. Ann Neurol 1987;22(4):533–4.
9. Steele, JC, Richardson, JC, Olszewski, J. Progressive supranuclear palsy. A heterogeneous degeneration involving the brain stem, basal ganglia and cerebellum with vertical gaze and pseudobulbar palsy, nuchal dystonia and dementia. Arch Neurol 1964;10:333–59.
10. Gibb, WR, Luthert, PJ, Marsden, CD. Corticobasal degeneration. Brain 1989;112(Pt 5):1171–92.
11. Constantinidis, J, Richard, J, Tissot, R. Pick's disease. Histological and clinical correlations. Eur Neurol 1974;11(4):208–17.
12. Kertesz, A, Hudson, L, Mackenzie, IR, Munoz, DG. The pathology and nosology of primary progressive aphasia. Neurology 1994;44(11):2065–72.
13. Rascovsky, K, Hodges, JR, Knopman, D, Mendez, MF, Kramer, JH, Neuhaus, J, et al. Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain 2011;134(Pt 9):2456–77.
14. Gregory, CA, Hodges, JR. Clinical features of frontal lobe dementia in comparison to Alzheimer's disease. J Neural Transm Suppl 1996;47:103–23.
15. Cummings, JL, Duchen, LW. Kluver-Bucy syndrome in Pick disease: clinical and pathologic correlations. Neurology 1981;31(11):1415–22.
16. Miller, BL, Cummings, JL, Villanueva-Meyer, J, Boone, K, Mehringer, CM, Lesser, IM, et al. Frontal lobe degeneration: clinical, neuropsychological, and SPECT characteristics. Neurology 1991;41(9):1374–82.
17. Elfgren, C, Passant, U, Risberg, J. Neuropsychological findings in frontal lobe dementia. Dementia 1993;4(3–4):214–19.
18. Hodges, JR, Patterson, K, Ward, R, Garrard, P, Bak, T, Perry, R, et al. The differentiation of semantic dementia and frontal lobe dementia (temporal and frontal variants of frontotemporal dementia) from early Alzheimer's disease: a comparative neuropsychological study. Neuropsychology 1999;13(1):3140.
19. Graham, A, Davies, R, Xuereb, J, Halliday, G, Kril, J, Creasey, H, et al. Pathologically proven frontotemporal dementia presenting with severe amnesia. Brain 2005;128(Pt 3):597605.
20. Kertesz, A, Davidson, W, McCabe, P, Munoz, D. Behavioral quantitation is more sensitive than cognitive testing in frontotemporal dementia. Alzheimer Dis Assoc Disord 2003;17(4):223–9.
21. Grossman, M, Mickanin, J, Onishi, K, Hughes, E, D'Esposito, M, Ding, XS, et al. Progressive nonfluent aphasia: language, cognitive, and PET measures contrasted with probable Alzheimer's disease. J Cogn Neurosci 1996;8(2):135–54.
22. Cohen, L, Benoit, N, Van Eeckhout, P, Ducarne, B, Brunet, P. Pure progressive aphemia. J Neurol Neurosurg Psychiatry 1993;56(8):923–4.
23. Mesulam, MM, Grossman, M, Hillis, A, Kertesz, A, Weintraub, S. The core and halo of primary progressive aphasia and semantic dementia. Ann Neurol 2003;54 Suppl 5:S1114.
24. Karbe, H, Kertesz, A, Polk, M. Profiles of language impairment in primary progressive aphasia. Arch Neurol 1993;50(2):193201.
25. Weintraub, S, Rubin, NP, Mesulam, MM. Primary progressive aphasia. Longitudinal course, neuropsychological profile, and language features. Arch Neurol 1990;47(12):1329–35.
26. Gorno-Tempini, ML, Hillis, AE, Weintraub, S, Kertesz, A, Mendez, M, Cappa, SF, et al. Classification of primary progressive aphasia and its variants. Neurology 2011;76(11):1006–14.
27. Josephs, KA, Duffy, JR, Strand, EA, Machulda, MM, Senjem, ML, Master, AV, et al. Characterizing a neurodegenerative syndrome: primary progressive apraxia of speech. Brain 2012;135(Pt 5):1522–36.
28. Fukui, T, Sugita, K, Kawamura, M, Shiota, J, Nakano, I. Primary progressive apraxia in Pick's disease: a clinicopathologic study. Neurology 1996;47(2):467–73.
29. Kertesz, A, McMonagle, P, Blair, M, Davidson, W, Munoz, DG. The evolution and pathology of frontotemporal dementia. Brain 2005;128(Pt 9):19962005.
30. Appell, J, Kertesz, A, Fisman, M. A study of language functioning in Alzheimer patients. Brain Lang 1982;17(1):7391.
31. Whiteley, AM, Warrington, EK. Prosopagnosia: a clinical, psychological, and anatomical study of three patients. J Neurol Neurosurg Psychiatry 1977;40(4):395403.
32. Gorno-Tempini, ML, Dronkers, NF, Rankin, KP, Ogar, JM, Phengrasamy, L, Rosen, HJ, et al. Cognition and anatomy in three variants of primary progressive aphasia. Ann Neurol 2004;55(3):335–46.
33. Mesulam, M, Weintraub, S. Primary progressive aphasia: sharpening the focus on a clinical syndrome. In: Boller, F, Forrette, F, Khachaturian, Z, Poncet, M, Christen, Y, editors. Heterogeneity of Alzheimer's Disease Berlin: Springer-Verlag; 1992. p. 4366.
34. Mesulam, M, Wicklund, A, Johnson, N, Rogalski, E, Léger, GC, Rademaker, A, et al. Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia. Ann Neurol 2008;63(6):709–19.
35. Harris, JM, Gall, C, Thompson, JC, Richardson, AM, Neary, D, du Plessis, D, et al. Classification and pathology of primary progressive aphasia. Neurology 2013;81(21):1832–9.
36. Akelaitis, AJ. Atrophy of basal ganglia in Pick's disease. A clinicopathologic study. Arch Neurol Psychiatr 1944;51:2734.
37. Munoz-Garcia, D, Ludwin, SK. Classic and generalized variants of Pick's disease: a clinicopathological, ultrastructural, and immunocytochemical comparative study. Ann Neurol 1984;16(4):467–80.
38. Rebeiz, JJ, Kolodny, EH, Richardson, EP. Corticodentatonigral degeneration with neuronal achromasia. Arch Neurol 1968;18(1):2033.
39. Lang, AE, Bergeron, C, Pollanen, MS, Ashby, P. Parietal Pick's disease mimicking cortical-basal ganglionic degeneration. Neurology 1994;44(8):1436–40.
40. Lippa, CF, Smith, TW, Fontneau, N. Corticonigral degeneration with neuronal achromasia. A clinicopathologic study of two cases. J Neurol Sci 1990;98(2–3):301–10.
41. Kertesz, A, Munoz, DG. Pick's Disease and Pick Complex New York; Chichester: J. Wiley & Sons; 1998.
42. Kertesz, A, Martinez-Lage, P, Davidson, W, Munoz, DG. The corticobasal degeneration syndrome overlaps progressive aphasia and frontotemporal dementia. Neurology 2000;55(9):1368–75.
43. Armstrong, MJ, Litvan, I, Lang, AE, Bak, TH, Bhatia, KP, Borroni, B, et al. Criteria for the diagnosis of corticobasal degeneration. Neurology 2013;80(5):496503.
44. Pillon, B, Blin, J, Vidailhet, M, Deweer, B, Sirigu, A, Dubois, B, et al. The neuropsychological pattern of corticobasal degeneration: comparison with progressive supranuclear palsy and Alzheimer's disease. Neurology 1995;45(8):1477–83.
45. Feany, MB, Mattiace, LA, Dickson, DW. Neuropathologic overlap of progressive supranuclear palsy, Pick's disease and corticobasal degeneration. J Neuropathol Exp Neurol 1996;55(1):5367.
46. Houlden, H, Baker, M, Morris, HR, MacDonald, N, Pickering-Brown, S, Adamson, J, et al. Corticobasal degeneration and progressive supranuclear palsy share a common tau haplotype. Neurology 2001;56(12):1702–6.
47. Dickson, DW, Bergeron, C, Chin, SS, Duyckaerts, C, Horoupian, D, Ikeda, K, et al. Office of Rare Diseases neuropathologic criteria for corticobasal degeneration. J Neuropathol Exp Neurol 2002;61(11):935–46.
48. Mitsuyama, Y. Presenile dementia with motor neuron disease in Japan: clinico-pathological review of 26 cases. J Neurol Neurosurg Psychiatry 1984;47(9):953–9.
49. Neary, D, Snowden, JS, Mann, DM, Northen, B, Goulding, PJ, Macdermott, N. Frontal lobe dementia and motor neuron disease. J Neurol Neurosurg Psychiatry 1990;53(1):2332.
50. Von Braumuhl, A. Picksche krankheit und amyotrophische lateralsklerose. Allgemeine Z Psychiatr Psychol Med 1932;96:364–6.
51. Lomen-Hoerth, C, Anderson, T, Miller, B. The overlap of amyotrophic lateral sclerosis and frontotemporal dementia. Neurology 2002;59(7):1077–9.
52. Strong, MJ, Lomen-Hoerth, C, Caselli, RJ, Bigio, EH, Yang, W. Cognitive impairment, frontotemporal dementia, and the motor neuron diseases. Ann Neurol 2003;54 Suppl 5:S20–3.
53. Hodges, JR, Davies, R, Xuereb, J, Kril, J, Halliday, G. Survival in frontotemporal dementia. Neurology 2003;61(3):349–54.
54. Okamoto, K, Hirai, S, Yamazaki, T, Sun, XY, Nakazato, Y. New ubiquitin-positive intraneuronal inclusions in the extra-motor cortices in patients with amyotrophic lateral sclerosis. Neurosci Lett 1991;129(2):233–6.
55. Jackson, M, Lennox, G, Lowe, J. Motor neurone disease-inclusion dementia. Neurodegeneration 1996;5(4):339–50.
56. Morita, M, Al-Chalabi, A, Andersen, PM, Hosler, B, Sapp, P, Englund, E, et al. A locus on chromosome 9p confers susceptibility to ALS and frontotemporal dementia. Neurology 2006;66(6):839–44.
57. Vance, C, Al-Chalabi, A, Ruddy, D, Smith, BN, Hu, X, Sreedharan, J, et al. Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2–21.3. Brain 2006;129(Pt 4):868–76.
58. DeJesus-Hernandez, M, Mackenzie, IR, Boeve, BF, Boxer, AL, Baker, M, Rutherford, NJ, et al. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 2011;72(2):245–56.
59. Renton, AE, Majounie, E, Waite, A, Simón-Sánchez, J, Rollinson, S, Gibbs, JR, et al. A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron 2011;72(2):257–68.
60. Anderson, P. ALS and FTD: two sides of the same coin? Lancet Neurol 2013;12:937–8.
61. van Blitterswijk, M, DeJesus-Hernandez, M, Niemantsverdriet, E, Murray, ME, Heckman, MG, Diehl, NN, et al. Association between repeat sizes and clinical and pathological characteristics in carriers of C9ORF72 repeat expansions (Xpansize-72): a cross-sectional cohort study. Lancet Neurol 2013;12(10):978–88.
62. Hodges, JR, Davies, RR, Xuereb, JH, Casey, B, Broe, M, Bak, TH, et al. Clinicopathological correlates in frontotemporal dementia. Ann Neurol 2004;56(3):399406.
63. Neumann, M, Sampathu, DM, Kwong, LK, Truax, AC, Micsenyi, MC, Chou, TT, et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 2006;314(5796):130–3.
64. Mackenzie, IR, Neumann, M, Baborie, A, Sampathu, DM, Du Plessis, D, Jaros, E, et al. A harmonized classification system for FTLD-TDP pathology. Acta Neuropathol 2011;122(1):111–13.
65. Munoz, DG, Neumann, M, Kusaka, H, Yokota, O, Ishihara, K, Terada, S, et al. FUS pathology in basophilic inclusion body disease. Acta Neuropathol 2009;118(5):617–27.
66. Neumann, M, Rademakers, R, Roeber, S, Baker, M, Kretzschmar, HA, Mackenzie, IR. A new subtype of frontotemporal lobar degeneration with FUS pathology. Brain 2009;132(Pt 11):2922–31.
67. Mackenzie, IR, Neumann, M, Bigio, EH, Cairns, NJ, Alafuzoff, I, Kril, J, et al. Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations. Acta Neuropathol 2009;117(1):1518.
68. Snowden, JS, Rollinson, S, Thompson, JC, Harris, JM, Stopford, CL, Richardson, AM, et al. Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations. Brain 2012;135(Pt 3):693708.
69. Roberson, ED. Mouse models of frontotemporal dementia. Ann Neurol 2012;72(6):837–49.
70. Munoz, DG, Woulfe, J, Kertesz, A. Argyrophilic thorny astrocyte clusters in association with Alzheimer's disease pathology in possible primary progressive aphasia. Acta Neuropathol 2007;114(4):347–57.
71. Josephs, KA, Hodges, JR, Snowden, JS, Mackenzie, IR, Neumann, M, Mann, DM, et al. Neuropathological background of phenotypical variability in frontotemporal dementia. Acta Neuropathol 2011;122(2):137–53.
72. Rohrer, JD, Lashley, T, Schott, JM, Warren, JE, Mead, S, Isaacs, AM, et al. Clinical and neuroanatomical signatures of tissue pathology in frontotemporal lobar degeneration. Brain 2011;134(Pt 9):2565–81.
73. Menon, R, Baborie, A, Jaros, E, Mann, DM, Ray, PS, Larner, AJ. What's in a name? Neuronal intermediate filament inclusion disease (NIFID), frontotemporal lobar degeneration-intermediate filament (FTLD-IF) or frontotemporal lobar degeneration-fused in sarcoma (FTLD-FUS)? J Neurol Neurosurg Psychiatry 2011;82(12):1412–14.
74. Mackenzie, IR, Foti, D, Woulfe, J, Hurwitz, TA. Atypical frontotemporal lobar degeneration with ubiquitin-positive, TDP-43-negative neuronal inclusions. Brain 2008;131(Pt 5):1282–93.
75. Lesage, S, Le Ber, I, Condroyer, C, Broussolle, E, Gabelle, A, Thobois, S, et al. C9orf72 repeat expansions are a rare genetic cause of parkinsonism. Brain 2013;136(Pt 2):385–91.
76. Bozeat, S, Gregory, CA, Ralph, MA, Hodges, JR. Which neuropsychiatric and behavioural features distinguish frontal and temporal variants of frontotemporal dementia from Alzheimer's disease? J Neurol Neurosurg Psychiatry 2000;69(2):178–86.
77. Harris, JM, Gall, C, Thompson, JC, Richardson, AM, Neary, D, du Plessis, D, et al. Sensitivity and specificity of FTDC criteria for behavioral variant frontotemporal dementia. Neurology 2013;80(20):1881–7.
78. Alladi, S, Xuereb, J, Bak, T, Nestor, P, Knibb, J, Patterson, K, et al. Focal cortical presentations of Alzheimer's disease. Brain 2007;130(Pt 10):2636–45.
79. Chaal, S, Rowe, J. Dopamine transporter (dat) imaging can be normal with neuropathologically confirmed corticobasal degeneration. J Neurol Neurosurg Psychiatry 2013;84(11):e2.
80. Shelley, BP, Hodges, JR, Kipps, CM, Xuereb, JH, Bak, TH. Is the pathology of corticobasal syndrome predictable in life? Mov Disord 2009;24(11):1593–9.
81. Mathew, R, Bak, TH, Hodges, JR. Diagnostic criteria for corticobasal syndrome: a comparative study. J Neurol Neurosurg Psychiatry 2012;83(4):405–10.
82. Tang-Wai, D, Lewis, P, Boeve, B, Hutton, M, Golde, T, Baker, M, et al. Familial frontotemporal dementia associated with a novel presenilin-1 mutation. Dement Geriatr Cogn Disord 2002;14(1):1321.
83. Halliday, GM, Song, YJ, Lepar, G, Brooks, WS, Kwok, JB, Kersaitis, C, et al. Pick bodies in a family with presenilin-1 Alzheimer's disease. Ann Neurol 2005;57(1):139–43.
84. Dermaut, B, Kumar-Singh, S, Engelborghs, S, Theuns, J, Rademakers, R, Saerens, J, et al. A novel presenilin 1 mutation associated with Pick's disease but not beta-amyloid plaques. Ann Neurol 2004;55(5):617–26.
85. Irwin, DJ, McMillan, CT, Toledo, JB, Arnold, SE, Shaw, LM, Wang, LS, et al. Comparison of cerebrospinal fluid levels of tau and Aβ 1–42 in Alzheimer disease and frontotemporal degeneration using 2 analytical platforms. Arch Neurol 2012;69(8):1018–25.
86. Bathgate, D, Snowden, JS, Varma, A, Blackshaw, A, Neary, D. Behaviour in frontotemporal dementia, Alzheimer's disease and vascular dementia. Acta Neurol Scand 2001;103(6):367–78.
87. Greene, JD, Hodges, JR, Ironside, JW, Warlow, CP. Progressive aphasia with rapidly progressive dementia in a 49 year old woman. J Neurol Neurosurg Psychiatry 1999;66(2):238–43.
88. Forman, MS, Farmer, J, Johnson, JK, Clark, CM, Arnold, SE, Coslett, HB, et al. Frontotemporal dementia: clinicopathological correlations. Ann Neurol 2006;59(6):952–62.
89. Mead, S, Poulter, M, Beck, J, Webb, TE, Campbell, TA, Linehan, JM, et al. Inherited prion disease with six octapeptide repeat insertional mutation – molecular analysis of phenotypic heterogeneity. Brain 2006;129(Pt 9):2297–317.
90. Kipps, CM, Hodges, JR, Hornberger, M. Nonprogressive behavioural frontotemporal dementia: recent developments and clinical implications of the ‘bvFTD phenocopy syndrome’. Curr Opin Neurol 2010;23(6):628–32.
91. Piguet, O, Hornberger, M, Mioshi, E, Hodges, JR. Behavioural-variant frontotemporal dementia: diagnosis, clinical staging, and management. Lancet Neurol 2011;10(2):162–72.