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  • Print publication year: 2010
  • Online publication date: October 2010

8 - Cosmetic psychopharmacology: drugs that enhance wellbeing, performance, and creativity

from Part 1 - Theory

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Åkerstedt, T. & Ficca, G. (1997). Alertness-enhancing drugs as a countermeasure to fatigue in irregular work hours. Chronobiology International, 14, 145–58.
Amiri, S., Mohammadi, M. R., Mohammadi, al. (2008). Modafinil as a treatment for attention-deficit/hyperactivity disorder in children and adolescents: a double blind, randomized clinical trial. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 32(1), 145–9. Epub August 8, 2007.
Arrington, M. (2008). How many silicon valley startup executives are hopped up on provigil?, July 15, 2008. November 23, 2008.
Avois, L., Robinson, N., Saudan, al. (2006). Central nervous system stimulants and sport practice. British Journal of Sports Medicine, 40(Suppl. 1), 116–20.
Babcock, Q. & Byrne, T. (2000). Student perceptions of methylphenidate abuse at a public liberal arts college. Journal of American College Health, 49, 143–5.
Ballon, J. S. & Feifel, D. (2006). A systematic review of modafinil: potential clinical uses and mechanisms of action. Journal of Clinical Psychiatry, 67(4), 554–66.
Baranski, J. V., Pigeau, R., Dinich, P. & Jacobs, I. (2004). Effects of modafinil on cognitive and meta-cognitive performance. Human Psychopharmacology, 19, 323–32.
Biederman, J., Swanson, J. M., Wigal, S. al. (2005). Efficacy and safety of modafinil film-coated tablets in children and adolescents with attention-deficit/hyperactivity disorder: results of a randomized, double-blind, placebo-controlled, flexible-dose study. Pediatrics, 116(6), e777–84.
Bramstedt, K. A. (2007). Caffeine use by children: the quest for enhancement. Substance Use & Misuse, 42(8), 1237–51.
Brantigan, C. O., Brantigan, T. A. & Joseph, N. (1982). Effect of beta blockade and beta stimulation on stage fright. American Journal of Medicine, 72(1), 88–94.
Broderick, P. & Benjamin, A. B. (2004). Caffeine and psychiatric symptoms: a review. Journal of the Oklahoma State Medical Association, 97(12), 538–42.
Brower, K. J., Blow, F. C., Beresford, T. P. & Fuelling, C. (1989). Anabolic-androgenic steroid dependence. Journal of Clinical Psychiatry, 50(1), 31–2.
Brower, K. J., Eliopulos, G. al. (1990). Evidence of physical and psychological dependence on anabolic androgenic steroids in weight lifters. American Journal of Psychiatry, 147(4), 510–12.
Brower, K. J., Blow, F. C., Young, J. P. & Hill, E. M. (1991). Symptoms and correlates of anabolic-androgenic steroid dependence. British Journal of Addiction, 86, 759–68.
Bryant, H. (2005). Juicing the Game. New York: Viking.
Caldwell, J. A. Jr, Caldwell, J. L., Smythe, N. K. 3rd & Hall, K. K. (2000). A double-blind, placebo-controlled investigation of the efficacy of modafinil for sustaining the alertness and performance of aviators: a helicopter simulator study. Psychopharmacology (Berlin), 150(3), 272–82.
Canceso, J. (2005). Juiced. New York: Harper Collins.
Carneiro, J. R., Nader, A. C., Oliveira, J. E., da Silveira, V. G. & Barroso, F. L. (2006). Past use of amphetamines in candidates for gastric bypass surgery in a university hospital. Obesity Surgery, 16(1), 31–4.
Carter, O. L., Burr, D. C., Pettigrew, J. al. (2005). Using psilocybin to investigate the relationship between attention, working memory, and the serotonin 1A and 2A receptors. Journal of Cognitive Neuroscience, 17(10), 1497–508.
Cassidy, J. (2008). Birdies in a bottle. Men’s Vogue, April 2008, p.72.
CDC (2002). Annual smoking-attributable mortality, years of potential life lost, and economic costs – United States, 1995–1999. Morbidity and Mortality Weekly Report, 51, 300–3.
Chatterjee, A. (2004). Cosmetic neurology: the controversy over enhancing movement, mentation, and mood. Neurology, 63, 968–74.
Colman, E. (2005). Anorectics on trial: a half century of federal regulation of prescription appetite suppressants. Annals of Internal Medicine, 143(5), 380–5.
Csordas, T. J., Storck, M. J. & Strauss, M. (2008). Diagnosis and distress in Navajo healing. Journal of Nervous and Mental Disease, 196(8), 585–96.
Dahlsgaard, K., Peterson, C. & Seligman, M. E. P. (2005). Shared virtue: the convergence of valued human strengths across culture and history. Review of General Psychology, 9, 203–13.
De Silva, D. A., Wong, M. C., Lee, M. P., Chen, C. L. & Chang, H. M. (2007). Amphetamine-associated ischemic stroke: clinical presentation and proposed pathogenesis. Journal of Stroke & Cerebrovascular Diseases, 16(4), 185–6.
Drug and Alcohol Services Information System (DASIS) Report, 9/12/04, accessed at, February 15, 2006.
Dupont, R. L., Coleman, J. J., Bucher, R. H. & Wilford, B. B. (2008). Characteristics and motives of college students who engage in nonmedical use of methylphenidate. American Journal of Addiction, 17(3), 167–71.
Elliott, R., Sahakian, B. J., Matthews, al. (1997). Effects of methylphenidate on spatial working memory and planning in healthy young adults. Psychopharmacology, 131, 196–206.
Escher, M., Desmeules, J., Giostra, al. (2001). Hepatitis associated with kava, a herbal remedy for anxiety. British Medical Journal, 322, 139.
Farah, M. J., Illes, J., Cook-Deegan, al. (2004). Neurocognitive enhancement: what can we do and what should we do?Nature Reviews Neuroscience, 5(5), 421–5.
Farah, M. J., Haimm, C., Sankoorikal, G. & Chatterjee, A. (2008). When we enhance cognition with Adderall, do we sacrifice creativity? A preliminary study. Psychopharmacology (Berlin), November 15 [Epub ahead of print].
Ferreira, S. E., de Mello, M.T., Pompeia, S. & de Souza-Formigoni, M. L. (2006). Effects of energy drink ingestion on alcohol intoxication. Alcoholism: Clinical and Experimental Research, 30, 598–605.
Frias, C. (2006). Baseball and amphetamines. Palm Beach Post, Sunday, April 2.
Gable, R. S. (2007). Risk assessment of ritual use of oral dimethyltryptamine (DMT) and harmala alkaloids. Addiction, 102(1), 24–34.
Galanter, M. & Kleber, H. D. (2004). Textbook of Substance Abuse Treatment, 3rd edn. Washington: American Psychiatric Publishing.
Gill, M., Haerich, P., Westcott, K., Godenick, K. L. & Tucker, J. A. (2006). Cognitive performance following modafinil versus placebo in sleep-deprived emergency physicians: a double-blind randomized crossover study. Academic Emergency Medicine, 13(2), 158–65. Epub January 25, 2006. Erratum in: Academic Emergency Medicine, 13(4), 477.
Grade, C., Redford, B., Chrostowski, J., Toussaint, L. & Blackwell, B. (1998). Methylphenidate in early poststroke recovery: a double-blind, placebo controlled study. Archives of Physical Medicine and Rehabilitation, 79, 1047–50.
Griffiths, R. R., Richards, W. A., McCann, U. & Jesse, R. (2006). Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance. Psychopharmacology (Berlin), 187(3), 268–83; discussion 284–92. Epub July 7, 2006.
Griffiths, R. R., Richards, W. A., Johnson, M. W., McCann, U. D. & Jesse, R. (2008). Mystical-type experiences occasioned by psilocybin mediate the attribution of personal meaning and spiritual significance 14 months later. Journal of Psychopharmacology, 22(6), 621–32. Epub July 1, 2008.
Grob, C. S., McKenna, D. J., Callaway, J. al. (1996). Human psychopharmacology of hoasca, a plant hallucinogen used in ritual context in Brazil. Journal of Nervous and Mental Disease, 184, 86–94.
Halpern, J. H., Shuster, T. D., Siegel, A. J. & Naidoo, U. (2008). MDMA-assisted therapy in people with anxiety related to advanced stage cancer., accessed November 27, 2008.
Harman, W. W., McKim, R. H., Mogar, R. E., Fadiman, J. & Stolaroff, M. J. (1966). Psychedelic agents in creative problem-solving: a pilot study. Psychedelic Reports, 19, 211–27.
Horne, J. A. & Reyner, L. A. (2001). Beneficial effects of an “energy drink” given to sleepy drivers. Amino Acids, 20(1), 83–9.
Huxley, A. (1954). The Doors of Perception. London: Chatto and Windus.
Ivy, J. L., Costill, D. L., Fink, W. J. & Lower, R. W. (1979). Influence of caffeine and carbohydrate feedings on endurance performance. Medicine & Science in Sports & Exercise, 11(1), 6–11.
Janiger, O. & Dobkin de Rios, M. (1989). LSD and creativity. Journal of Psychoactive Drugs, 21(1), 129–34.
Jarvis, M. J. (1993). Does caffeine intake enhance absolute levels of cognitive performance?Psychopharmacology, 110, 45–52.
Johnson, M. W., Richards, W. A. & Griffiths, R. R..(2008).Human hallucinogen research: guidelines for safety. Psychopharmacology, 22, 603, originally published online July 1, 2008.
Jones, M. T. (2007). The creativity of Crumb: research on the effects of psychedelic drugs on the comic art of Robert Crumb. Journal of Psychoactive Drugs, 39(3), 283–91.
Keepnews, O. (1988). The View from Within: Jazz Writings 1948–1987. New York: Oxford University Press, p. 91.
Kerr, B., Shafer, J., Chambers, C. & Hallowell, K. (1991). Substance use of creatively talented adults. Journal of Creative Behavior, 25(2), 145–53.
Kleber, H. D. (1967). Prolonged adverse reactions from unsupervised use of hallucinogenic drugs. Journal of Nervous and Mental Disease, 144(4), 308–19.
Kramer, P. D. (1993). Listening to Prozac, a Psychiatrist Explores Antidepressant Drugs and the Remaking of the Self. New York: Viking Books.
Kumar, R. (2008). Approved and investigational uses of modafinil: an evidence-based review. Drugs, 68(13), 1803–39.
Lagarde, D., Batejat, D., Van Beers, P., Sarafian, D. & Pradella, S. (1995). Interest of modafinil, a new psychostimulant, during a sixty-hour sleep deprivation experiment. Fundamental and Clinical Pharmacology, 9, 1–9.
Lane, J. R. & Connor, J. D. (1994). The influence of endogenous and exogenous sex hormones in adolescents with attention to oral contraceptives and anabolic steroids. Journal of Adolescent Health, 15(8), 630–4.
Lanni, C., Lenzken, S. C., Pascale, al. (2008). Cognition enhancers between treating and doping the mind. Pharmacology Research 57(3), 196–213. Epub February 15, 2008. Review.
Lapp, W. M., Collins, R. L. & Izzo, C. V. (1994). On the enhancement of creativity by alcohol: pharmacology or expectation?American Journal of Psychology, 107(2), 173–206.
Laseter, J. T. & Russell, J. A. (1991). Anabolic steroid-induced tendon pathology: a review of the literature. Medicine & Science in Sports & Exercise, 23(1), 1–3.
Leake, J. (2004). Downtime is over as pill offers 24-hour living. Timesonline. July 4, 2004., accessed November 23, 2008.
Lukas, S. E. (2009).The pharmacology of anabolic androgenic steroids. In Principles of Addiction Medicine, 4th edn, ed. R. K. Ries. Philadelphia PA: Lippincott Williams & Wilkins, Inc, pp. 251–63.
McCabe, S. E., Knight, J. R., Teter, C. J. & Wechsler, H. (2005). Non-medical use of prescription stimulants among US college students: prevalence and correlates from a national survey. Addiction, 100, 96–106.
McCusker, R. R., Goldberger, B. A. & Cone, E. J. (2003). Caffeine content of specialty coffees. Journal of Analytical Toxicology, 27(7), 520–2.
McCusker, R. R., Goldberger, B. A. & Cone, E. J. (2006). Caffeine content of energy drinks, carbonated sodas, and other beverages. Journal of Analytical Toxicology, 30(2), 112–14.
McEvoy, A. W., Kitchen, N. D. & Thomas, D. G. (2000). Intracerebral hemorrhage and drug abuse in young adults. British Journal of Neurosurgery, 14(5), 449–54.
Maher, B. (2008). Poll results: look who’s doping. Nature, 452(7188), 674–5.
Malinauskas, B. M., Aeby, V. G., Overton, R. F., Carpenter-Aeby, T. & Barber-Heidal, K. (2007). A survey of energy drink consumption patterns among college students. Nutrition Journal, 6, 35.
Martinez, M., Devenport, L., Saussy, J. & Martinez, J. (2002). Drug-associated heat stroke. Southern Medical Journal, 95(8), 799–802.
Mehta, M. A., Owen, A. M., Sahakian, B. al. (2000). Methylphenidate enhances working memory by modulating discrete frontal and parietal lobe regions in the human brain. Journal of Neuroscience, 20, RC65.
Metzner, R. (1998). Hallucinogenic drugs and plants in psychotherapy and shamanism. Journal of Psychoactive Drugs, 30(4), 333–41.
Miskowiak, K., Inkster, B., Selvaraj, al. (2008). Erythropoietin improves mood and modulates the cognitive and neural processing of emotion 3 days post administration. Neuropsychopharmacology, 33(3), 611–18. Epub May 2, 2007.
Mithoefer, M. (2008). A test of MDMA-assisted psychotherapy in people with posttraumatic stress disorder NCT00090064., accessed November 27, 2008.
Monitoring the Future (MFT), University of Michigan, December 2005.
Morein-Zamir, S., Turner, D. C. & Sahakian, B. J. (2007). A review of the effects of modafinil on cognition in schizophrenia. Schizophrenia Bulletin, 33(6), 1298–306. Epub July 18, 2007.
Mottram, D. R. (2005). Drugs in Sport. New York: Taylor & Francis, p. 283.
Nawrot, P., Jordan, S., Eastwood, al. (2003). Effects of caffeine on human health. Food Additives and Contaminants, 20(1), 1–30.
O’Brien, M. C., McCoy, T., Rhodes, S. D., Wagoner, A. & Wolfson, M. (2008). Caffeinated cocktails: energy drink consumption, high-risk drinking, and alcohol-related consequences among college students. Academic Emergency Medicine, 15, 453–60.
Pary, R., Lewis, S., Matuschka, al. (2002). Attention deficit disorder in adults. Annals of Clinical Psychiatry, 14, 105–11.
Perry, P. J., Andersen, K. H. & Yates, W. R. (1990). Illicit anabolic steroid use in athletes, a case series analysis. American Journal of Sports Medicine, 18(4), 422–8.
Pope, H. G. & Katz, D. L. (1988). Affective and psychotic symptoms associated with anabolic steroid use. American Journal of Psychiatry, 145(4), 487–90.
Pope, H. G., Phillips, K. A. & Olivardia, R. (2000). The Adonis Complex, The Secret Crisis of Male Body Obsession. New York: The Free Press.
President’s Council on Bioethics. (2003). Beyond Therapy: Biotechnology and the Pursuit of Human Improvement. Washington DC: Dana Press.
Post, F. (1996). Verbal creativity, depression and alcoholism: an investigation of one hundred American and British writers. British Journal of Psychiatry, 168, 545–55.
Rao, A., Hu, H. & Nobre, A. C. (2005). The effects of combined caffeine and glucose drinks on attention in the human brain. Nutritional Neuroscience, 8(3), 141–53.
Reissig, C. J., Strain, E. C. & Griffiths, R. R. (2009). Caffeinated energy drinks – a growing problem. Drug and Alcohol Dependence, 99(1–3), 1–10.
Rosenthal, R. N. & Solhkhah, R. (2005). Psychopharmacology of club drugs. In Clinical Manual of Addiction Psychopharmacology, eds. H. R. Kranzler & D. A. Ciraulo. Washington DC: American Psychiatric Publishing, Inc, pp. 243–67.
Savitz, J. B. & Ramesar, R. S. (2004). Genetic variants implicated in personality: a review of the more promising candidates. American Journal of Medical Genetics B Neuropsychiatric Genetics, 131B(1), 20–32.
Sessa, B. (2005). Can psychedelics have a role in psychiatry once again?British Journal of Psychiatry, 186, 457–8.
Sessa, B. (2007). Is there a case for MDMA-assisted psychotherapy in the UK?Journal of Psychopharmacology, 21(2), 220–4. Erratum in Journal of Psychopharmacology, 22(6), 699, 2008.
Silverberg, D. S., Iaina, A., Wexler, D. & Blum, M. (2001). The pathological consequences of anaemia. Clinical & Laboratory Haematology, 23(1), 1–6. UI: 11422223.
Smith, A. P. (2005). Caffeine at work. Human Psychopharmacology, 20, 441–5.
Spencer, T., Biederman, J., Wilens, al. (2001). Efficacy of a mixed amphetamine salts compound in adults with attention-deficit/hyperactivity disorder. Archives of General Psychiatry, 58(8), 784–5.
Sunram-Lea, S. I., Foster, J. K., Durlach, P. & Perez, C. (2002). The effect of retrograde and anterograde glucose administration on memory performance in healthy young adults. Behavioural Brain Research, 134, 505–16.
Swerdlow, N. R., Stephany, N., Wasserman, L. al. (2003). Dopamine agonists disrupt visual latent inhibition in normal males using a within-subject paradigm. Psychopharmacology (Berlin), 169(3–4), 314–20. Epub February 28, 2003.
Teitelman, E. (2001). Off-label uses of modafinil. American Journal of Psychiatry, 158, 1341.
Tinklenberg, J. R., Darley, C. F., Roth, W. T., Pfefferbaum, A. & Kopell, B. S. (1978). Marijuana effects on associations to novel stimuli. Journal of Nervous and Mental Disease, 166(5), 362–4.
Trenton, A. J. & Currier, G. W. (2006). Behavioural manifestations of anabolic steroid use. CNS Drugs, 19(7), 571–95.
Trice, I. & Haymes, E. M. (1995). Effects of caffeine ingestion on exercise-induced changes during high-intensity, intermittent exercise. International Journal of Sport Nutrition, 5(1), 37–44.
Turner, D. C., Clark, L., Dowson, J., Robbins, T. W. & Sahakian, B. J. (2004). Modafinil improves cognition and response inhibition in adult attention deficit/hyperactivity disorder. Biological Psychiatry, 55(10), 1031–40.
van der Watt, G., Laugharne, J. & Janca, A. (2008). Complementary and alternative medicine in the treatment of anxiety and depression. Current Opinion in Psychiatry, 21, 37–42.
Volkow, N. D. & Swanson, J. M. (2008). The action of enhancers can lead to addiction. Nature, 451, 31.
Walker-Batson, D., Curtis, S., Natarajan, al. (2001). A double-blind, placebo controlled study of the use of amphetamine in the treatment of aphasia. Stroke, 32, 2093–8.
Wasson, R. G. (1980). The Wondrous Mushroom: Mycolatry in Mesoamerica. New York: McGraw-Hill.
Westover, A. N., Nakonezny, P. A. & Haley, R. W. (2008). Acute myocardial infarction in young adults who abuse amphetamines. Drug & Alcohol Dependence, 96(1–2), 49–56.
Westreich, L. M. (2008). Anabolic androgenic steroid use pharmacology, prevalence, and psychiatric aspects. Psychiatric Times, 25(1).
Wilens, T. E. (2008). Effects of methylphenidate on the catecholaminergic system in attention-deficit/hyperactivity disorder. Journal of Clinical Psychopharmacology, 28 (3Suppl. 2), S46–53.
Williams, S. J., Seale, C., Boden, S., Lowe, P. & Steinberg, D. L. (2008). Waking up to sleepiness: modafinil, the media and the pharmaceuticalisation of everyday/night life. Sociology of Health & Illness, 30(6), 839–55. Epub April 25, 2008.
Yesavage, J. A., Mumenthaler, M. S., Taylor, J. al. (2002). Donepezil and flight simulator performance: effects on retention of complex skills. Neurology, 59(1), 123–5.
Zegans, L. S., Pollard, J. C. & Brown, D. (1967). The effects of LSD-25 on creativity and tolerance to regression. Archives of General Psychiatry, 16(6), 740–9.