Cavernous Malformations of the Nervous System

doi:10.1017/CBO9781139003636

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Cavernous Malformations of the Nervous System

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Cited by 12
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Marchi, Saverio Trapani, Eliana Corricelli, Mariangela Goitre, Luca Pinton, Paolo and Retta, Saverio Francesco 2016. Beyond multiple mechanisms and a unique drug: Defective autophagy as pivotal player in cerebral cavernous malformation pathogenesis and implications for targeted therapies. Rare Diseases, Vol. 4, Issue. 1, p. e1142640.

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De Luca, Elisa Pedone, Deborah Moglianetti, Mauro Pulcini, Daniele Perrelli, Andrea Retta, Saverio Francesco and Pompa, Pier Paolo 2018. Multifunctional Platinum@BSA–Rapamycin Nanocarriers for the Combinatorial Therapy of Cerebral Cavernous Malformation. ACS Omega, Vol. 3, Issue. 11, p. 15389.

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Perrelli, Andrea Bozza, Annalisa Ferraris, Chiara Osella, Sara Moglia, Andrea Mioletti, Silvia Battaglia, Luigi and Retta, Saverio Francesco 2023. Multidrug-Loaded Lipid Nanoemulsions for the Combinatorial Treatment of Cerebral Cavernous Malformation Disease. Biomedicines, Vol. 11, Issue. 2, p. 480.

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Gnanasekaran, Revathi Aickareth, Justin Hawwar, Majd Sanchez, Nickolas Croft, Jacob and Zhang, Jun 2023. CmPn/CmP Signaling Networks in the Maintenance of the Blood Vessel Barrier. Journal of Personalized Medicine, Vol. 13, Issue. 5, p. 751.

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Edited by Daniele Rigamonti, The Johns Hopkins University

Publisher: Cambridge University Press
Online publication date: September 2011
Print publication year: 2011
Online ISBN: 9781139003636
DOI: https://doi.org/10.1017/CBO9781139003636

Subjects: Neurology and Clinical Neuroscience, Medicine

93.99 (GBP)

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Cavernous Malformations of the Nervous System
Edited by Daniele Rigamonti
Online ISBN: 9781139003636

Book DOI: https://doi.org/10.1017/CBO9781139003636
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Questions regarding the nature and appropriate management of cavernous malformation (CM) have clouded researchers and those faced with making clinical decisions for several decades. CMs may be seen as an incidental finding on MRI studies, or they may present with symptoms, such as seizures or intracranial hemorrhage, often causing severe neurologic deficit. Cavernous Malformations of the Nervous System provides a comprehensive and authoritative review of the current practice in diagnosis and management of these cerebrovascular disorders. Emphasis has been laid on the understanding of basic sciences with chapters committed to understanding of CCM1, 2 and 3 genes and their role in CCM biology, as well as clinical genetics. Controversial topics which continue to pose treatment challenges such as safety of anticoagulation and prophylactic management during pregnancy are also discussed. This book will be of interest to basic science researchers, neurosurgeons and vascular neurologists both in academic institutions and private practice.

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Cavernous Malformations of the Nervous System

This Book has been cited by the following publications. This list is generated based on data provided by Crossref.

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Contents

Cavernous Malformations of the Nervous System - Half title page
pp i-ii

Cavernous Malformations of the Nervous System - Title page
pp iii-iii

Copyright page
pp iv-iv

Dedication
pp v-vi

Contents
pp vii-viii

Preface
pp ix-ix

Contributors
pp x-xii

Section 1 - Biology
pp 1-48

Chapter 1 - Pathology of cavernous malformations
pp 1-8

Chapter 2 - Epidemiology and natural history of cavernous malformations
pp 9-14

Chapter 3 - Familial cavernous malformations: a historical survey
pp 15-20

Chapter 4 - Clinical and molecular genetics of cerebral cavernous malformations
pp 21-30

Chapter 5 - Molecular biology of cerebral cavernous malformation
pp 31-40

Chapter 6 - Cavernous malformations and radiation
pp 41-48

Section 2 - Clinical features, imaging and diagnostic work-up
pp 49-102

Chapter 7 - Neuroimaging of cavernous malformations
pp 49-64

Chapter 8 - Clinical features and medical management of cavernous malformations
pp 65-78

Chapter 9 - Hemorrhage: new and recurrent
pp 79-90

Chapter 10 - Cavernous malformations and epilepsy: medical management of seizures and the presurgical evaluation of medically intractable epilepsy
pp 91-102

Section 3 - Therapy
pp 103-180

Chapter 11 - The pros and cons of conservative and surgical treatment of cavernous malformations
pp 103-114

Chapter 12 - Surgical treatment of cavernous malformations associated with epilepsy
pp 115-126

Chapter 13 - Surgery of spinal cavernous malformations
pp 127-134

Chapter 14 - Surgical treatment of cavernous malformations in children
pp 135-142

Chapter 15 - Resection of cavernous malformations of the brainstem
pp 143-160

Chapter 16 - Principles for managing cavernous malformations in eloquent locations
pp 161-172

Chapter 17 - Radiosurgery of cavernous malformations: the Pittsburgh experience
pp 173-180

Section 4 - Special aspects
pp 181-190

Chapter 18 - Genetic counseling
pp 181-184

Chapter 19 - Special problems in cavernous malformations: migraine, pregnancy, hormonal replacement, anticoagulation, NSAIDs, stress, and altitude elevation changes
pp 185-190

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Cavernous Malformations of the Nervous System

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