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Case 6 - A Challenging Thesis

Published online by Cambridge University Press:  09 January 2021

By
Pedro Rosa-Neto ,
Monica Shin ,
Tharick A. Pascoal ,
Mira Chamoun ,
Jean-Paul Soucy ,
Sarinporn Manitsirikul  and
Serge Gauthier
Edited by
Pedro Rosa-Neto  and
Serge Gauthier
Pedro Rosa-Neto
Affiliation:
McGill University, Montréal
Serge Gauthier
Affiliation:
McGill University, Montréal
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Summary

An 80-year-old man came to the consultation with problems in writing a thesis.

Type
Chapter
Information
Case Studies in Dementia
Common and Uncommon Presentations
 , pp. 22 - 25
Publisher: Cambridge University Press
Print publication year: 2021

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References

Further Reading

Attems, J, Jellinger, KA. Amyloid and tau: neither chicken nor egg but two partners in crime! Acta Neuropathol. 2013;126:619–621.CrossRefGoogle ScholarPubMed
Braak, H, Del Tredici, K. Are cases with tau pathology occurring in the absence of Aβ deposits part of the AD-related pathological process? Acta Neuropathol. 2014;128:767–772.CrossRefGoogle ScholarPubMed
Crary, JF, Trojanowski, JQ, Schneider, JA, et al. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathol. 2014;128:755–766.CrossRefGoogle Scholar
Delacourte, A. The natural and molecular history of Alzheimer’s disease. J Alzheimer Dis. 2006;9:187–194.CrossRefGoogle ScholarPubMed
Jellinger, KA. Complex tauopathies versus tangle predominant dementia. Acta Neuropathol. 2011;122(4):515.CrossRefGoogle ScholarPubMed
Jellinger, KA, Attems, J. Neurofibrillary tangle-predominant dementia: comparison with classical Alzheimer disease. Acta Neuropathol. 2006;113:107–117.CrossRefGoogle ScholarPubMed
Jellinger, KA, Alafuzoff, I, Attems, J, et al. PART, a distinct tauopathy, different from classical sporadic Alzheimer disease. Acta Neuropathol. 2015;129:757–762.CrossRefGoogle Scholar
Josephs, KA, Murray, ME, Tosakulwong, N, et al. Tau aggregation influences cognition and hippocampal atrophy in the absence of beta-amyloid: a clinico-imaging-pathological study of primary age-related tauopathy (PART). Acta Neuropathol. 2017;133:705–715.CrossRefGoogle ScholarPubMed
Masahito, Y. Senile dementia of the neurofibrillary tangle type (tangle-only dementia): neuropathological criteria and clinical guidelines for diagnosis. Neuropathol. 2003;23:311–317.Google Scholar
Weller, RO, Hawkes, CA, Carare, RO, Hardy, J. Does the difference between PART and Alzheimer’s disease lie in the age-related changes in cerebral arteries that trigger the accumulation of Aβ and propagation of tau? Acta Neuropathol. 2015;129:763–766.CrossRefGoogle ScholarPubMed

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