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  • Print publication year: 2008
  • Online publication date: October 2014

9 - Management of cervical intraepithelial neoplasia during pregnancy

from SECTION 3 - Gynaecological Cancers and Precancer


Cervical intraepithelial neoplasia (CIN) has a high incidence in the reproductive age groups. Colposcopy is safe in pregnancy and, as a result of the extension of the squamous-columnar junction (SCJ) to the ectocervix, it is also satisfactory in the majority of the cases. Generally, the rate of CIN progression during pregnancy is known to be small, and no evidence reveals an increase in the risk of invasive cervical cancer in pregnancy. Infants can acquire human papillomavirus (HPV) from their mothers during labour as they descend through an infected genital tract. A caesarean section should not be recommended for a pregnant woman with CIN solely for the purpose of prevention of HPV transmission to the infant. Modifications of the management principles are required mainly because treatment of CIN during pregnancy can cause serious morbidity and should only be reserved for special circumstances.