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Chapter 19 - Cognitive and behavioral abnormalities of vascular cognitive impairment

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1.Pasquier, F, Leys, D (1997). Why are stroke patients prone to develop dementia? J Neurol 244(3):135–42.
2.Bowler, JV, Hachinski, V (1995). Vascular cognitive impairment: a new approach to vascular dementia. Baillires Clin Neurol 4(2):357–76.
3.Lee, DY, Lee, JH, Ju, YS et al. (2002). The prevalence of dementia in older people in an urban population of Korea: the Seoul study. J Am Geriatr Soc 50(7):1233–9.
4.Zhang, ZX, Zahner, GE, Roman, GC et al. (2005). Dementia subtypes in China: prevalence in Beijing, Xian, Shanghai, and Chengdu. Arch Neurol 62(3):447–53.
5.Dong, MJ, Peng, B, Lin, XT et al. (2007). The prevalence of dementia in the People’s Republic of China: a systematic analysis of 1980–2004 studies. Age Ageing 36(6):619–24.
6.Yanagihara, T (2002). Vascular dementia in Japan. Ann N Y Acad Sci 977:24–8.
7.Kokmen, E, Whisnant, JP, O’Fallon, WN, Chu, CP, Beard, CM (1996). Dementia after ischemic stroke: a populationbased study in Rochester, Minnesota (1960–1984). Neurology 46:154–9.
8.Andersen, G, Vestergaard, K, Riis, JY, Ingeman-Nielsen, M (1996). Intellectual impairment in the first year following stroke, compared to an age-matched population sample. Cerebrovasc Dis 6:363–9.
9.Tatemichi, TK, Paik, M, Bagiella, E et al. (1994). Risk of dementia after stroke in a hospitalized cohort: results of a longitudinal study. Neurology 44:1885–91.
10.Gorelick, PB, Scuteri, A, Black, SE et al. (2011) Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke Association. AHA/ASA Scientific Statement. Stroke. 42(9):2672–713.
11.American Psychiatric Association (1994). Diagnostic and Statistical Manual of Mental Disorders, 4th edn. Washington, DC: American Psychiatric Association.
12.World Health Organization (1993). International Classification of Disease (ICD-1 0): Classification of Mental and Behavioral Disorders. Diagnostic Criteria for Research. Geneva: World Health Organization.
13.Chui, HC, Victoroff, JI, Margolin, D et al. (1992). Criteria for the diagnosis of ischemic vascular dementia proposed by the State of California Alzheimer’s Disease Diagnostic and Treatment Centers. Neurology 42:473–80.
14.Roman, GC, Tatemichi, TK, Erkinjuntti, T et al. (1993). Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology 31:269–82.
15.Roman, GC, Tatemichi, TK, Erkinjuntti, T et al. (1993). Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology 43:250–60.
16.Roman, GC, Tatemichi, TK, Erkinjuntti, T et al. (1993). Vascular dementia: diagnostic criteria for research studies - Report of the NINDS-AIREN International Workshop. Neurology 43:1609–11.
17.Hachinski, VC, Iliff, LD, Zilhka, E et al. (1975). Cerebral blood flow in dementia. Arch Neurol 32(9):632–7.
18.Moroney, JT, Bagiella, E, Desmond, DW et al. (1997). Meta-analysis of the Hachinski Ischemic Score in pathologically verified dementias. Neurology 49:1096–105.
19.De Reuck, J, Sieben, G, De Coster, W, van der Eecken, H (1981). Stroke pattern and topography of cerebral infarcts. A clinicopathological study. Eur Neural 20(5):411–15.
20.Erkinjuntti, T (1987). Types of multi-infarct dementia. Acta Neurol Scand 75(6):391–9.
21.Erkinjuntti, T, Sawada, T, Whitehouse, PJ (1999). The Osaka Conference on Vascular Dementia 1998. Alzheimer Dis Assoc Disord 13(Suppl 3):S1–3.
22.Benson, DF, Cummings, JL (1982). Angular gyrus syndrome simulating Alzheimer’s disease. Arch Neurol 39(10):616–20.
23.Tatemichi, TK, Foulkes, MA, Mohr, JP et al. (1990). Dementia in stroke survivors in the Stroke Data Bank cohort. Prevalence, incidence, risk factors, and computed tomographic findings. Stroke 21(6):858–66.
24.Brust, J, Sawada, T, Kazui, S (2001). Anterior cerebral artery. In Stroke Syndrome, 2nd edn, eds. Bogousslavsky, J, Caplan, L. Cambridge, UK: Cambridge University Press, 439–60.
25.Absher, JR, Cummings, JL (1995). Neurobehavioral examination of frontal lobe functions. Aphasiology 9:181–92.
26.Cummings, JL (1993). Frontal-subcortical circuits and human behavior. Arch Neurol 50(8):873–80.
27.Hahm, DS, Kang, Y, Cheong, SS, Na, DL (2001). A compulsive collecting behavior following an A-com aneurysmal rupture. Neurology 56(3):398400.
28.Lhermitte, F, Pillon, B, Serdaru, M (1986). Human autonomy and the frontal lobes. Part I: imitation and utilization behavior: a neuropsychological study of 75 patients. Ann Neurol 19(4): 326–34.
29.Lhermitte, F (1983). “Utilization behaviour” and its relation to lesions of the frontal lobes. Brain 106(Pt 2):237–55.
30.Tranel, D (1994). “Acquired sociopathy”: the development of sociopathic behavior following focal brain damage. Prog Exp Pers Psychopathol Res 285–311.
31.Gazzaniga, MS, lvry, RB, Mangun, GR (2002). Emotion. In Cognitive Neuroscience: The Biology of the Mind 2nd edn, ed. Gazzaniga, MS, Ivry, RB, Mangun, GR. New York: WW Norton, 537–76.
32.Heilman, KM, Watson, RT (1991). Intentional motor disorders. In Frontal Lobe Function and Dysfunction, ed. Levin, HS, Eisenberg, HM, Benton, AL. New York: Oxford University Press, pp. 199213.
33.Wernicke, E (1874). Der Aphasische Symptomenkomplex. Breslau: Cohn and Weigart.
34.Geschwind, N (1965). Disconnexion syndromes in animals and man. I. Brain 88(2):237–94.
35.Geschwind, N (1965). Disconnexion syndromes in animals and man. II. Brain 88(3):585644.
36.Heilman, KM, van den Abell, T (1979). Right hemispheric dominance for mediating cerebral activation. Neuropsychologia 17(3–4):315–21.
37.Meador, KJ, Watson, RT, Bowers, D, Heilman, KM (1986). Hypometria with hemispatial and limb motor neglect. Brain 109(Pt 2):293305.
38.Heilman, KM, Bowers, D, Coslett, HB, Whelan, H, Watson, RT (1985). Directional hypokinesia: prolonged reaction times for leftward movements in patients with right hemisphere lesions and neglect. Neurology 35(6):855–9.
39.Kertesz, A, Nicholson, I, Cancelliere, A, Kassa, K, Black, SE (1985). Motor impersistence: a right hemisphere syndrome. Neurology 35(5):662–6.
40.Sandson, J, Albert, ML (1987). Perseveration in behavioral neurology. Neurology 37(11):1736–41.
41.Kolb, B, Whishaw, IQ (2003). Disconnection syndromes. In Fundamentals of Human Neuropsychology, 5th edn, ed. Kolb, B, Whishaw, IQ. New York: Worth, pp. 426–46.
42.Seo, SW, Jung, K, You, H et al. (2007). Dominant limb motor impersistence associated with callosal disconnection. Neurology 68(11):862–4.
43.Starkstein, SE, Robinson, RG (1991). The role of the frontal lobes in affective disorder following stroke. In Frontal Lobe Function and Dysfunction, ed. Levin, HS, Eisenberg, HM, Benton, AL. New York: Oxford University Press, pp. 288303.
44.Damasio, AR, Anderson, SW (2003). The frontal lobes. In Clinical Neuropsychology, 4th edn, ed. Heilman, KM, Valenstein, E. New York: Oxford University Press, 404–46.
45.Andrew, J, Nathan, PW (1964). Lesion on the anterior frontal lobes and disturbances of micturition and defecation. Brain 87:233–62.
46.Ropper, AH, Brown, RH, Brown, RJ (2005). Disorders of speech and language. Adams and Victor’s Principles of Neurology, 8th edn. New York: McGraw-Hill, pp. 413–32.
47.Zangwill, OL (1979). Two cases of crossed aphasia in dextrals. Neuropsychologia 17(2):167.
48.Broca, P (1977). Remarks on the seat of the faculty of articulate speech, followed by the report of a case of aphemia (loss of speech). In Neurologic Classics in Modern Translation, eds. Rottenberg, DA, Hochberg, FH. New York: Hafner Press, 136–49.
49.Damasio, H (1981). Cerebral localization of the aphasias. In Acquired Aphasia, ed. Sarno, MT. Orlando, FL: Academic Press, pp. 2755.
50.Benson, DF (1988). Classical syndromes of aphasia. In Handbook of Neuropsychology, vol.l, eds. Boiler, F, Grafman, J. Amsterdam: Elsevier Science, 267280.
51.Damasio, H, Damasio, AR (1983). The localization of lesions in conduction aphasia. In Localization and Neuroimaging in Neuropsychology, ed. Kertesz, A. Orlando, FL: Academic Press, pp. 231–43.
52.Devinsky, O (1992). Aphasia. In Behavioral Neurology 100 Maxims. St. Louis MO: Mosby Year Book, 88130.
53.Freedman, M, Alexander, MP, Naeser, MA (1984). Anatomic basis of transcortical motor aphasia. Neurology 34(4): 409–17.
54.Alexander, MP, Hiltbrunner, B, Fischer, RS (1989). Distributed anatomy of transcortical sensory aphasia. Arch Neurol 46(8):885–92.
55.Mesulam, MM, van Hoesen, GW, Pandya, DN, Geschwind, N (1977). Limbic and sensory connections of the inferior parietal lobule (area PG) in the Rhesus monkey: a study with a new method for horseradish per oxidase histochemistry. Brain Res 136(3):393414.
56.Gerstmann, J (1940). Syndrome of finger agnosia, disorientation for right and left, agraphia and acalculia. Arch Neurol Psychiatry 44:398408.
57.Benton, AL, Varney, NR, Hamsher, KD (1978). Visuospatial judgment. A clinical test. Arch Neurol 35(6):364–7.
58.Heilman, KM, van den Abell, T (1980). Right hemisphere dominance for attention: the mechanism underlying hemispheric asymmetries of inattention (neglect). Neurology 30(3):327–30.
59.Benton, AL, Tranel, D (1993). Visuoperceptual, visuospatial, and visuoconstructive disorders. In Clinical Neuropsychology 3rd edn, eds. Heilman, KM and Valenstein, E. New York: Academic Press, 165213.
60.Farah, MJ (2003). Disoders of visual-spatial perception and cognition. In Clinical Neuropsychology. 4th edn, ed. Heilman, KM, Valenstein, E. New York: Oxford University Press, pp. 146–60.
61.Heilman, KM, Rothi, LJG (2003). Apraxia. In Clinical Neuropsychology, 4th edn, ed. Heilman, KM, Valenstein, E. New York: Oxford University Press, pp. 215–35.
62.Heilman, KM, Rothi, LJG (2003). Neglect and related disorders. In Clinical Neuropsychology, 4th edn, ed. Heilman, KM, Valenstein, E. New York: Oxford University Press, pp. 296346.
63.Mort, DJ, Malhotra, P, Mannan, SK et al. (2003). The anatomy of visual neglect. Brain 126:1986–97.
64.Vallar, G, Bottini, G, Paulesu, E (2003). Neglect syndromes: the role of the parietal cortex. Adv Neurol 93 :293319.
65.Karnath, HO, Fruhmann Berger, M, Kuker, W, Rorden, C (2004). The anatomy of spatial neglect based on voxel-wise statistical analysis: a study of 140 patients. Cereb Cortex 14:1164–72.
66.Karnath, HO, Zopf, R, Johannsen, L et al. (2005). Normalized perfusion MRI to identify common areas of dysfunction: patients with basal ganglia neglect. Brain 128:2462–9.
67.Hillis, AE, Newhart, M, Heidler, J et al. (2005). Anatomy of spatial attention: insights from perfusion imaging and hemispatial neglect in acute stroke. J Neurosci 25:3161–7.
68.Babinski, J (1914). Contribusion a l’etude des troubles mentaux clans l’hemiplegie organique cerebrate (anosognosie). Rev Neural 27:845–7.
69.Beschin, N, Robertson, IH (1997). Personal versus extrapersonal neglect: a group study of their dissociation using a reliable clinical test. Cortex 33(2):379–84.
70.Tucker, DM, Watson, RT, Heilman, KM (1977). Discrimination and evocation of affectively intoned speech in patients with right parietal disease. Neurology 27(10):947–50.
71.Ross, ED (1981). The aprosodias. Functional–anatomic organization of the affective components of language in the right hemisphere. Arch Neurol 38(9):561–9.
72.Mesulam, MM, Waxman, SG, Geschwind, N, Sabin, TD (1976). Acute confusional states with right middle cerebral artery infarctions. J Neurol Neurosurg Psychiatry 39(1):84–9.
73.Mori, E, Yamadori, A (1987). Acute confusional state and acute agitated delirium. Occurrence after infarction in the right middle cerebral artery territory. Arch Neurol 44(11):1139–43.
74.Starkstein, SE, Robinson, RG, Price, TR (1987). Comparison of cortical and subcortical lesions in the production of poststroke mood disorders. Brain 110(Pt 4): 1045–59.
75.Kim, JS, Choi-Kwon, S (2000). Poststroke depression and emotional incontinence: correlation with lesion location. Neurology 54(9):1805–10.
76.Fisher, CM (1986). The posterior cerebral artery syndrome. Can J Neurol Sci 13(3):232–9.
77.Critchley, M (1951). Types of visual perseveration: “paliopsia” and “illusory visual spread”. Brain 74(3):267–99.
78.Lance, JW (1976). Simple formed hallucinations confined to the area of a specific visual field defect. Brain 99(4):719–34.
79.Brust, JC, Behrens, MM (1977). “Release hallucinations” as the major symptom of posterior cerebral artery occlusion: a report of 2 cases. Ann Neurol 2(5):432–6.
80.De Renzi, E, Zambolin, A, Crisi, G (1987). The pattern of neuropsychological impairment associated with left posterior cerebral artery infarcts. Brain 110(Pt 5):1099–116.
81.Geschwind, N, Fusillo, M (1966). Color-naming defects in association with alexia. Arch Neurol 115(2):137–46.
82.Kertesz, A, Sheppard, A, MacKenzie, R (1982). Localization in transcortical sensory aphasia. Arch Neurol 39(8):475–8.
83.Luders, H, Lesser, RP, Hahn, J et al. (1991). Basal temporal language area. Brain 114(Pt 2):743–54.
84.Kwon, JC, Lee, HJ, Chin, J et al. (2002). Hanja alexia with agraphia after left posterior inferior temporal lobe infarction: a case study. J Korean Med Sci 17(1):91–5.
85.Kawamura, M, Hirayama, K, Hasegawa, K, Takahashi, N, Yamaura, A (1987). Alexia with agraphia of kanji (Japanese morphograms). J Neurol Neurosurg Psychiatry 50(9):1125–9.
86.Soma, Y, Sugishita, M, Kitamura, K, Maruyama, S, Imanaga, H (1989). Lexical agraphia in the Japanese language. Pure agraphia for Kanji due to left posteroinferior temporal lesions. Brain 112(Pt 6): 1549–61.
87.Benson, DF, Marsden, CD, Meadows, JC (1974). The amnesic syndrome of posterior cerebral artery occlusion. Acta Neurol Scand 50(2):133–45.
88.Kanwisher, N, McDermott, J, Chun, MM (1997). The fusiform face area: a module in human extrastriate cortex specialized for face perception. J Neurosci 17(11):4302–11.
89.Piercy, MF, Hecaen, H, de Ajuriaguerra, J (1960). Constructional apraxia associated with unilateral cerebral lesions. Brain 83:225–42.
90.Fisher, CM (1982). Disorientation for place. Arch Neurol 39(1):33–6.
91.Park, KC, Jeong, Y, Hwa Lee, B et al. (2005). Left hemispatial visual neglect associated with a combined right occipital and splenial lesion: another disconnection syndrome, Neurocase 11(5):310–18.
92.Park, KC, Lee, BH, Kim, EJ et al. (2006). Deafferentation disconnection neglect induced by posterior cerebral artery infarction. Neurology 66(1):5661.
93.Poppel, E, Held, R, Frost, D (1973). Residual visual function after brain wounds involving the central visual pathways in man. Nature 243(5405):295–6.
94.Aldrich, MS, Alessi, AG, Beck, RW, Gilman, S (1987). Cortical blindness: etiology, diagnosis, and prognosis. Ann Neurol 21(2):149–58.
95.Ungerleider, LG, Mishkin, M (1982). Two cortical visual systems. In Analysis of Visual Behavior, ed. Ingle, DJ, Goodale, MA, Mansfield, RJW. Cambridge, MA: MIT Press, pp. 549–86.
96.Hecaen, H, de Ajuriaguerra, J (1954). Balint’s syndrome (psychic paralysis of visual fixation) and its minor forms. Brain 77(3):373400.
97.Albert, ML, Soffer, D, Silverberg, R, Reches, A (1979).The anatomic basis of visual agnosia. Neurology 29(6):876–9.
98.Damasio, A, Yamada, T, Damasio, H, Corbett, J, McKee, J (1980). Central achromatopsia: behavioral, anatomic, and physiologic aspects. Neurology 30(10):1064–71.
99.Damasio, AR, Damasio, H, van Hoesen, GW (1982). Prosopagnosia: anatomic basis and behavioral mechanisms. Neurology 32(4):331–41.
100.Ringelstein, EB, Zeumer, H, Angelou, D (1983). The pathogenesis of strokes from internal carotid artery occlusion. Diagnostic and therapeutical implications. Stroke 14(6):867–75.
101.Ringelstein, EB, Berg-Dammer, E, Zeumer, H (1983). The so-called atheromatous pseudo-occlusion of the internal carotid artery. A diagnostic and therapeutical challenge. Neuroradiology 25(3):147–55.
102.Bogousslavsky, J, Regli, F (1986). Unilateral watershed cerebral infarcts. Neurology 36(3):373–7.
103.Bogousslavsky, J, Regli, F (1992). Centrum ovale infarcts: subcortical infarction in the superficial territory of the middle cerebral artery. Neurology 42(10):1992–8.
104.Hashiguchi, S, Mine, H, Ide, M, Kawachi, Y (2000). Watershed infarction associated with dementia and cerebral atrophy. Psychiatry Clin Neurosci 54(2): 163–8.
105.Antonelli Incalzi, R, Marra, C, Giordano, A et al. (2003). Cognitive impairment in chronic obstructive pulmonary disease: A neuropsychological and SPECT study. J Neurol 250(3):325–32.
106.Lass, P, Buscombe, JR, Harber, M, Davenport, A, Hilson, AJ (1999). Cognitive impairment in patients with renal failure is associated with multiple-infarct dementia. Clin Nucl Med 24:561–5.
107.Zuccala, G, Onder, G, Pedone, C (2001). For the GIFAONLUS Study Group. Hypotension and cognitive impairment: selective association in patients with hearing failure. Neurology 57(11):1986–92.
108.Tsuda, Y, Yamada, K, Hayakawa, T et al. (1994). Cortical blood flow and cognition after extracranial-intracranial bypass in a patient with severe carotid occlusive lesions. Acta Neurochir (Wien) 129(3–4):198204.
109.Roman, GC (2004). Brain hypoperfusion: a critical factor in vascular dementia. Neurol Res 26:454–8.
110.Pullicino, PM, Caplan, LR, Hommel, M (1993). Advances in Neurology, Vol. 62: Cerebral Small Artery Disease. New York: Raven Press.
111.Crystal, HA, Dickson, DW, Sliwinski, MJ et al. (1993). Pathological markers associated with normal aging and dementia in the elderly. Ann Neurol 34:566–73.
112.Kumral, E, Evyapan, D, Balkir, K (1999). Acute caudate vascular lesions. Stroke 30(1): 100–8.
113.Mendez, MF, Adams, NL, Lewandowsky, K (1989). Neurobehavioral changes associated with caudate lesions. Neurology 39:349–54.
114.Caplan, LR, Schmahmann, JD, Kase, CS et al. (1990). Caudate infarcts. Arch Neurol 47:133–43.
115.Kawamura, M, Takahashi, N, Hirayama, K (1988). Hemichorea and its denial in a case of caudate infarction diagnosed by magnetic resonance imaging. J Neurol Neurosurg Psychiatry 51:590–1.
116.Richfield, EK, Twyman, R, Berent, S (1987). Neurological syndrome following bilateral damage to the head of the caudate nuclei. Ann Neurol 22:768–71.
117.Meguro, K, Meguro, M, Akanuma, K (2012). Recurrent delusional ideas due to left caudate head infarction, without dementia. Psychogeriatrics 12:5861.
118.Pozzilli, C, Passafiume, D, Bastianello, S, D’Antona, R, Lenzi, GL (1987). Remote effects of caudate hemorrhage: a clinical and functional study. Cortex 23:341–9.
119.McMurtray, AM, Sultzer, DL, Monserratt, L, Yeo, T, Mendez, MF (2008). Content-specific delusions from right caudate lacunar stroke: association with prefrontal hypometabolism. J Neuropsychiatry Clin Neurosci 20:62–7.
120.Alexander, MP, Naeser, MA, Palumbo, CL (1987). Correlation of subcortical CT lesion sites and aphasia profiles. Brain 110:961–91.
121.Bhatia, KP, Marsden, CD (1994). The behavioural and motor consequences of focal lesions of the basal ganglia in man. Brain 117(Pt 4):859–76.
122.Maraganore, DM, Harding, AE, Marsden, CD (1991). A clinical and genetic study of familial Parkinson’s disease. Mov Disord 6(3):205–11.
123.Laplane, D, Attal, N, Sauron, B, de Billy, A, Dubois, B (1992). Lesions of basal ganglia due to disulfiram neurotoxicity. J Neurol Neurosurg Psychiatry 55(10):925–9.
124.Kim, SH, Park, KH, Sung, YH, Lee, YB, Park, HM, Shin, DJ (2008). Dementia mimicking a sudden cognitive and behavioral change induced by left globus pallidus infarction: review of two cases. J Neurol Sci 272:178–82.
125.Tatemichi, TK, Desmond, DW, Prohovnik, I et al. (1992a). Confusion and memory loss from capsular genu infarction: a thalamocortical disconnection syndrome? Neurology 42:1966–79.
126.Kooistra, CA, Heilman, KM (1988). Memory loss from a subcortical white matter infarct. J Neural Neurosurg Psychiatry 51:866–9.
127.Lai, C, Okada, Y, Sadoshima, S et al. (1990). A case of left internal capsular infarction with auditory hallucination and peculiar amnesia and dysgraphia. No To Shinkei 42:873–77.
128.Terao, Y, Bandou, M, Nagura, H et al. (1991). Persistent amnestic syndrome due to infarction of the genu of the left internal capsule. Rinsho Shinkeigaku 31:1002–6.
129.Chukwudelunzu, FE, Meschia, JF, Graff-Radford, NR, Lucas, JA (2001). Extensive metabolic and neuropsychological abnormalities associated with discrete infarction of the genu of the internal capsule. J Neurol Neurosurg Psychiatry 71(5):658–62.
130.Yamanaka, K, Fukuyama, H, Kimura, J (1996). Abulia from unilateral capsular genu infarction: report of two cases. J Neurol Sci 143:181–4.
131.Bogousslavsky, J, Regli, F (1990). Capsular genu syndrome. Neurology 40:1499–502.
132.Oh, JH, Ahn, BY, Jo, MK et al. (2011). Obsessive-compulsive behavior disappearing after left capsular genu infarction. Case Rep Neurol 3:1820.
133.Tatemichi, TK, Steinke, W, Duncan, C et al. (1992b). Paramedian thalamopeduncular infarction: clinical syndromes and magnetic resonance imaging. Ann Neurol 32(2):162–71.
134.Klingler, J, Gloor, P (1960). The connections of the amygdala and of the anterior temporal cortex in the human brain. J Camp Neurol 115:333–69.
135.Krettek, JE, Price, JL (1977). The cortical projections of the mediodorsal nucleus and adjacent thalamic nuclei in the rat. J Camp Neurol 171:157–91.
136.Nieuwenhuys, R, Voogd, J, van Huijzen, C (1988). The Human Central Nervous System: A Synopsis and Atlas. New York: Springer-Verlag.
137.Hwang, W, Oh, YA, Jang, SM et al. (2010). A case report of three-dimensional fiber tractography of anterior thalamic radiation in a capsular genu infarction. Demen Neurocog Disord 9:36–9.
138.von Cramon, DY, Hebel, N, Schuri, U (1985). A contribution to the anatomical basis of thalamic amnesia. Brain 108(Pt 4):9931008.
139.Graff-Radford, NR, Tranel, D, van Hoesen, GW, Brandt, JP (1990). Diencephalic amnesia. Brain 113(Pt 1):125.
140.Aggleton, JP, Saunders, RC (1997). The relationships between temporal lobe and diencephalic structures implicated in anterograde amnesia. Memory: 5:4971.
141.Ghika-Schmid, F, Bogousslavsky, J (2000). The acute behavioral syndrome of anterior thalamic infarction: a prospective study of 12 cases. Ann Neurol 48(2):220–7.
142.Carrera, E, Michel, P, Bogousslavsky, J (2004). Anteromedian, central, and posterolateral infarcts of the thalamus: three variant types. Stroke 35:2826–31.
143.Benson, DF, Djenderedjian, A, Miller, EL et al. (1996). Neural basis of confabulation. Neurology 46:1239–43.
147.Nishio, Y, Hashimoto, M, Ishii, K, Mori, E (2011). Neuroanatomy of a neurobehavioral disturbance in the left anterior thalamic infarction. J Neurol Neurosurg Psychiatry 82:1195–200.
148.Muneoka, K, Igawa, M, Kida, J, Mikami, T, Ishihara, I, Uchida, J, Uchida, S, Hirasawa, H (2008). In a case of Alzheimer’s disease, aggressiveness disappeared after an infarction in the anterior thalamic nucleus. Cerebrovasc Dis 26:664–5.
149.van der Werf, YD, Witter, MP, Uylings, HB, Jolles, J (2000). Neuropsychology of infarctions in the thalamus: a review. Neuropsychologia 38(5):613–27.
150.Daum, I, Ackermann, H (1994). Frontal-type memory impairment associated with thalamic damage. Int J Neurosci 77(3–4):187–98.
151.Linek, V, Sonka, K, Bauer, J (2005). Dysexecutive syndrome following anterior thalamic ischemia in the dominant hemisphere. J Neurol Sci 229–230:117–20.
152.Carrera, E, Bogousslavsky, J (2006). The thalamus and behavior: effects of anatomically distinct strokes. Neurology 66:1817–23.
153.Kim, EJ, Lee, DK, Kang, DH et al. (2005). Ipsilateral ptosis associated with anterior thalamic infarction. Cerebrovasc Dis 20:410–11.
154.Castaigne, P, Lhermitte, F, Buge, A et al. (1981). Paramedian thalamic and midbrain infarct: clinical and neuropathological study. Ann Neurol 10:127–48.
155.Graff-Radford, NR, Damasio, H, Yamada, T, Eslinger, PJ, Damasio, AR (1985). Nonhaemorrhagic thalamic infarction. Clinical, neuropsychological and electrophysiological findings in four anatomical groups defined by computerized tomography. Brain 108(Pt 2):485516.
156.Bogousslavsky, J, Regli, F, Uske, A (1988). Thalamic infarcts: clinical syndromes, etiology, and prognosis. Neurology 38(6):837–48.
157.Chung, CS, Caplan, LR, Han, W et al. (1996). Thalamic haemorrhage. Brain 119(Pt 6): 1873–86.
158.Schmahmann, JD (2003). Vascular syndromes of the thalamus. Stroke 34:2264–78.
159.Hermann, DM, Siccoli, M, Brugger, P, Wachter, K, Mathis, J, Achermann, P, Bassetti, CL (2008). Evolution of neurological, neuropsychological and sleep-wake disturbances after paramedian thalamic stroke. Stroke 39:62–8.
160.Weidauer, S, Nichtweiss, M, Zanella, FE, Lanfermann, H (2004). Assessment of paramedian thalamic infarcts: MR imaging, clinical features and prognosis. Eur Radiol 14(9):1615–26.
161.Mennemeier, M, Fennell, E, Valenstein, E, Heilman, KM (1992). Contributions of the left intralaminar and medial thalamic nuclei to memory. Comparisons and report of a case. Arch Neurol 49(10):1050–8.
162.Perren, F, Clarke, S, Bogousslavsky, J (2005). The syndrome of combined polar and paramedian thalamic infarction. Arch Neurol 62:1212–16.
163.Eslinger, PJ, Warner, GC, Grattan, LM, Easton, JD (1991). “Frontal lobe” utilization behavior associated with paramedian thalamic infarction. Neurology 41 (3):450–2.
164.Muller, A, Baumgartner, RW, Rohrenbach, C, Regard, M (1999). Persistent Kluver-Bucy syndrome after bilateral thalamic infarction. Neuropsychiatry Neuropsychol Behav Neurol 12(2):136–9.
165.Crail-Melendez, D, Atriano-Mendieta, C, Carrillo-Meza, R, Ramirez-Bermudez, J 2013. Schizophrenia-like psychosis associated with right lacunar thalamic infarct. Neurocase 19:22–6.
166.Ioannidis, AE, Kimiskidis, VK, Loukopoulou, E et al. (2013). Apathy, cognitive dysfunction and impaired social cognition in a patient with bilateral thalamic infarction. Neurocase 19:513–20.
167.van der Werf YD, Scheltens P, Lindeboom, J et al. (2003b). Deficits of memory, executive functioning and attention following infarction in the thalamus; a study of 22 cases with localised lesions. Neuropsychologia 41:1330–44.
168.Botez, MI, Barbeau, A (1971). Role of subcortical structures, and particularly of the thalamus, in the mechanisms of speech and language. A review. Int J Neurol 8:300–20.
169.Fisher, CM (1965). Lacunes: small deep cerebral infarcts. Neurology 15:774–84.
170.Pantoni, L, Garcia, JH (1997). Pathogenesis of leukoaraiosis: a review. Stroke. 28:652–9.
171.Thore, CR, Anstrom, JA, Moody, DM et al. (2007). Morphometric analysis of arteriolar tortuosity in human cerebral white matter of preterm, young, and aged subjects. J Neuropathol Exp Neurol 66:337–45.
172.Scheltens, P, Barkhof, F, Leys, D, Wolters, EC, Ravid, R, Kamphorst, W. (1995) Histopathologic correlates of white matter changes on MRI in Alzheimer’s disease and normal aging. Neurology 45:883–8.
173.Moody, DM, Brown, WR, Challa, VR, Ghazi-Birry, HS, Reboussin, DM (1997). Cerebral microvascular alterations in aging, leukoaraiosis, and Alzheimer’s disease. Ann N Y Acad Sci 826:103–16.
174.Gao, FQ, van Gaal, S. L-CNRJSCBJBS. Does variable progression of incidental white matter hyperintensities in AD relate to venous insufficiency? Alzheimer’s and Dementia. 2008;4 (Suppl):T368–69.
175.Erkinjuntti, T, Inzitari, D, Pantoni, L et al. (2000). Research criteria for subcortical vascular dementia in clinical trials. J Neural Transm Suppl 59:2330.
176.Hijdra, A, Verbeeten, B Jr., Verhulst, JAPM (1990). Relation of leukoaraiosis to lesion type in stroke patients. Stroke 21:890–4.
177.Tatemichi, TK, Desmond, DW, Paik, M et al. (1993). Clinical determinants of dementia related to stroke. Ann Neurol 33(6):568–75.
178.Lee, JH, Kim, SH, Kim, GH et al. (2011) Identification of pure subcortical vascular dementia using 11C-Pittsburgh compound B. Neurology 5;77(1):1825.
179.Kim, CH, Seo, SW, Kim, GH et al. (2012). Cortical thinning in subcortical vascular dementia with negative 11C-PiB PET. J Alzheimers Dis 31(2):315–23.
180.Kim, HJ, Kang, SJ, Kim, C et al. (2013). The effects of small vessel disease and amyloid burden on neuropsychiatric symptoms: a study among patients with subcortical vascular cognitive impairments. Neurobiol Aging 34(7):1913–20.
181.Dubois, B, Slachevsky, A, Litvan, I, Pillon, B (2000). The FAB: a frontal assessment battery at bedside. Neurology 55(11):1621–6.
182.Desmond, DW, Erkinjuntti, T, Sano, M et al. (1999). The cognitive syndrome of vascular dementia: implications for clinical trials. Alzheimer Dis Assoc Disord 13(Suppl 3):S21–9.
183.Yoon, CW, Shin, JS, Kim, HJ et al. (2013) Cognitive deficits of pure subcortical vascular dementia vs. Alzheimer disease: PiB-PET-based study. Neurology 80(6):569–73.
184.Stuss, DT, Cummings, JL (1990). Subcortical vascular dementias. In Subcortical Dementia, ed. Cummings, JL. New York: Oxford University Press, pp. 145–63.
185.Pantoni, L, Garcia, JH, Brown, GG (1996). Vascular pathology in three cases of progressive cognitive deterioration. J Neurol Sci 135:131–9.
186.Roman, GC (1987). Senile dementia of the Bingswanger type: a vascular form of dementia in the elderly. JAMA 258:1782–8.
187.Kim, SH, Seo, SW, Go, SM et al. (2011) Pyramidal and extrapyramidal scale (PEPS): a new scale for the assessment of motor impairment in vascular cognitive impairment associated with small vessel disease. Clin Neurol Neurosurg. 113(3):181–7.
188.Cummings, JL, Benson, DF (1983). Dementia: A Clinical Approach. Boston, MA: Butterworth.
189.Baddeley, A (1986). Working Memory. New York: Oxford University Press.
190.Mega, MS, Cummings, JL (1994). Frontal subcortical circuits and neuropsychiatric disorders. J Neuropsychiatry Clin Neurosci 6:358–70.
191.Damasio, AR (1998). The somatic marker hypothesis and the possible functions of the prefrontal cortex. In The Prefrontal Cortex. Executive and Cognitive Functions, ed. Roberts, AC, Robbins, TW, Weiskrantz, L. New York: Oxford University Press, 3650.
192.Lamar, M, Podell, K, Carew, TG et al. (1997). Perseverative behavior in Alzheimer’s disease and subcortical ischemic vascular dementia. Neuropsychology 11(4):523–34.
193.Eslinger, PJ, Grattan, LM (1993). Frontal lobe and frontalstriatal substrates for different forms of human cognitive flexibility. Neuropsychologia 31(1):1728.
194.Boone, KB, Miller, BL, Lesser, IM et al. (1992). Neuropsychological correlates of white-matter lesions in healthy elderly subjects: a threshold effect. Arch Neurol 49:549–54.
195.Looi, JC, Sachdev, PS (1999). Differentiation of vascular dementia from AD on neuropsychological tests. Neurology 53(4):670–8.
196.Tierney, MC, Black, SE, Szalai, JP et al. (2001). Recognition memory and verbal fluency differentiate probable Alzheimer disease from subcortical ischemic vascular dementia. Arch Neurol 58(10):1654–9.
197.Lafosse, JM, Reed, BR, Mungas, D et al. (1997). Fluency and memory differences between ischemic vascular dementia and Alzheimer’s disease. Neuropsychology 11(4):514–22.
198.Schmidtke, K. Hill, M (2002). Neuropsychological differentiation of small vessel disease, Alzheimer’s disease and mixed dementia. J Neurol Sci 17(22):203–4.
199.Vuorinen, E, Laine, M, Rinne, J (2000). Common pattern of language impairment in vascular dementia and in Alzheimer disease. Alzheimer Dis Assoc Disord 14(2):81–6.
200.Baillon, S, Muhommad, S, Marudkar, M et al. (2003). Neuropsychological performance in Alzheimer’s disease and vascular dementia: comparisons in a memory clinic population. Int J Geriatr Psychiatry 18:602–8.
201.Cannata, AP, Alberoni, M, Franceschi, M, Mariani, C (2002). Frontal impairment in subcortical ischemic vascular dementia in comparison to Alzheimer’s disease. Dement Geriatr Cogn Disord 13:101–11.
202.Aharon-Peretz, J, Kliot, D, Tamer, R (2000). Behavioral differences between white matter lacunar dementia and Alzheimer’s disease: a comparison on the neuropsychiatric inventory. Dement Geriatr Cogn Disord 11(5):294–8.
203.Fuh, JL, Wang, SJ, Cummings, JL (2005). Neuropsychiatric profiles in patients with Alzheimer’s disease and vascular dementia. J Neurol Neurosurg Psychiatry 76(10):1337–41.
206.Padovani, A, Di Piero, V, Bragoni, M et al. (1995). Patterns of neuropsychological impairment in mild dementia: a comparison between Alzheimer’s disease and multi-infarct dementia. Acta Neurol Scand 92(6):433–42.
207.Shimokawa, A, Yatomi, N, Anamizu, S et al. (2000). Comprehension of emotions: comparison between Alzheimer type and vascular type dementias. Dement Geriatr Cogn Disord 11(5):268–74.
208.Rockwood, K, Bowler, J, Erkinjuntti, T, Hachinski, V, Wallin, A (1999). Subtypes of vascular dementia. Alzheimer Dis Assoc Disord 13(Suppl 3):S59–65.
209.Seo, SW, Ahn, J, Yoon, U et al. (2010). Cortical thinning in vascular mild cognitive impairment and vascular dementia of subcortical type. J Neuroimaging 20(1):3745.
210.Seo, SW, Cho, SS, Park, A, Chin, J, Na, DL (2009). Subcortical vascular versus amnestic mild cognitive impairment: comparison of cerebral glucose metabolism. J Neuroimaging 19(3):213–19.
211.Galluzzi, S, Sheu, CF, Zanetti, 0, Frisoni, GB (2005). Distinctive clinical features of mild cognitive impairment with subcortical cerebrovascular disease. Dement Geriatr Cogn Disord 19(4):196203.
212.Park, JH, Seo, SW, Kim, C et al. (2014) Effects of cerebrovascular disease and amyloid beta burden on cognition in subjects with subcortical vascular cognitive impairment. Neurobiol Aging 35(1):254–60.
213.Kim, SH, Kang, HS, Kim, HJ et al. (2013) Neuropsychiatric predictors of conversion to dementia both in patients with amnestic mild cognitive impairment and those with subcortical vascular MCI. Clin Neurol Neurosurg 115(8):1264–70.
214.Bogousslavsky, J, Regli, F, Assal, G (1986). The syndrome of unilateral tuberothalamic artery territory infarction. Stroke 17:434–41.
215.Heilman, KM, Rothi, LJ, Valenstein, E (1982). Two forms of ideomotor apraxia. Neurology 32(4):342–6.
216.Na, DL, Adair, JC, Williamson, DJ et al. (1998). Dissociation of sensory-attentional from motor-intentional neglect. J Neurol Neurosurg Psychiatry 64(3):331–8.
217.Ogden, JA (1985). Anterior-posterior interhemispheric differences in the loci of lesions producing visual hemineglect. Brain Cogn 4:5975.
218.Guberman, A, Stuss, D (1983). The syndrome of bilateral paramedian thalamic infarction. Neurology 33(5):540–6.