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Chapter 1 - Peripheral Blood Smear Review

from Section I - Peripheral Blood

Published online by Cambridge University Press:  25 November 2023

Silvia Tse Bunting
Affiliation:
Cleveland Clinic Florida Weston
Xiayuan Liang
Affiliation:
University of Colorado
Michele E. Paessler
Affiliation:
University of Pennsylvania School of Medicine
Satheesh Chonat
Affiliation:
Emory University, Atlanta
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Summary

Despite all the advances in laboratory medicine, microscopic review of the peripheral blood smear is still highly informative and clinically relevant and remains an indispensable diagnostic tool. In a pediatric hospital, a common and challenging request is the evaluation of a newborn blood smear. This chapter provides an overview of some of the characteristics of a newborn smear and common reactive conditions.

Blood smear evaluation is often performed for three essential reasons: first, to clarify a flagged result such as immature cells or a low platelet count to rule out pseudo-thrombocytopenia from platelet clumping; second, to evaluate the morphology of red blood cells, white blood cells, and platelets; and, third, to confirm morphologic findings identified by lab staff or an instrument [1]. The latter may be requested by a physician due to a clinical suspicion or by members of the laboratory staff for review of an abnormal finding.

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Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2023

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References

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