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26 - Cell Death in the Cardiovascular System

from Part II - Cell Death in Tissues and Organs

Published online by Cambridge University Press:  07 September 2011

Douglas R. Green
By
Vladimir Kaplinskiy ,
Martin R. Bennett  and
Richard N. Kitsis
Edited by
John C. Reed
Douglas R. Green
Affiliation:
St. Jude Children's Research Hospital, Memphis, Tennessee
Vladimir Kaplinskiy
Affiliation:
Albert Einstein College of Medicine
Martin R. Bennett
Affiliation:
Addenbrooke’s Hospital, UK
Richard N. Kitsis
Affiliation:
Albert Einstein College of Medicine
John C. Reed
Affiliation:
Sanford-Burnham Medical Research Institute, La Jolla, California
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Summary

Introduction

Cardiovascular disease is the most common cause of death in the world. Regulated forms of cell death play critical roles in cardiovascular disease. In particular, apoptosis and necrosis, and perhaps autophagic cell death, are causal components in the pathogenesis of the most common and lethal cardiovascular syndromes: myocardial infarction and heart failure. This chapter summarizes the mechanisms and physiologic impact of regulated cell death in the cardiovascular system.

Type
Chapter
Information
Apoptosis
Physiology and Pathology
 , pp. 295 - 312
Publisher: Cambridge University Press
Print publication year: 2011

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