Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-77c89778f8-m8s7h Total loading time: 0 Render date: 2024-07-22T12:08:41.572Z Has data issue: false hasContentIssue false

Chapter 9 - The Reproductive Endocrinology of Contraception

from Section 2A - Sexual and Reproductive Healthcare: Contraception

Published online by Cambridge University Press:  16 January 2024

By
Sven O. Skouby  and
Kresten Rubeck Petersen
Edited by
Johannes Bitzer  and
Tahir A. Mahmood
Johannes Bitzer
Affiliation:
University Women's Hospital, Basel
Tahir A. Mahmood
Affiliation:
Victoria Hospital, Kirkcaldy
Get access

Summary

The provision of quality reproductive health services and education, access to reliable and safe contraception, and safe abortion services and post-abortion care, are important to empower women to achieve their goals and ambitions, avoid unwanted pregnancy and ensure any pregnancy occurs at the right time for them. The introduction of the first oral contraceptive pill in 1960 sparked a movement to put women in control of their sexual and reproductive health through the use of effective modern methods of contraception. A number of technological developments and advances in the understanding of hormones between the 1930s and 1950s made the first steps toward a hormonal contraception possible; understanding of the effects of steroid hormones was advanced, progesterone was characterized, and the first synthetic progestin (norethindrone/norethisterone) was developed.

Type
Chapter
Information
Textbook of Contraception, Sexual and Reproductive Health , pp. 61 - 70
Publisher: Cambridge University Press
Print publication year: 2024

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

DiMarco, CS, Speroff, L, Glass, RH, Kase, NG (eds.). Clinical gynecologic endocrinology and infertility. 6th edition. Baltimore, MD: Lippincott, Williams & Wilkins, 1999.Google Scholar
Moghissi, KS. Gonadotropin releasing hormones: Clinical applications in gynecology. J Reprod Med. 1990;35(12):1097–1107.Google ScholarPubMed
Moghissi, KS. Vulnerable targets for contraception in the female. Global Libra Women’s Med FIGO. 2009.Google Scholar
Skorupskaite, K, George, JT, Anderson, RA. The kisspeptin–GnRH pathway in human reproductive health and disease. Hum Reprod Update. 2014;20(4):485–500.CrossRefGoogle ScholarPubMed
Adashi, EY. Intraovarian peptides: Stimulators and inhibitors of follicular growth and differentiation. Endocrinol Metab Clin of North Am. 1992;21(1):1–17.CrossRefGoogle ScholarPubMed
Chengalvala, MV, Meade, EH, Cottom, JE et al. Regulation of female fertility and identification of future contraceptive targets. Curr Pharm Des. 2006;12(30):3915–28.CrossRefGoogle ScholarPubMed
ES H. Transport of spermatozoa in the female reproductive tract. Am J Obstet Gynecol. 1973;115(5):703–17.Google Scholar
Lyons, RA, Saridogan, E, Djahanbakhch, O. The reproductive significance of human Fallopian tube cilia. Hum Reprod Update. 2006;12(4):363–72.CrossRefGoogle ScholarPubMed
Deligdisch, L. Hormonal pathology of the endometrium. Mod Pathol. 2000;13(3):285–94.CrossRefGoogle ScholarPubMed
Salamonsen, LA. Tissue injury and repair in the female human reproductive tract. Reproduction. 2003;125(3):301–11.CrossRefGoogle ScholarPubMed
Hickey, M, Salamonsen, LA. Endometrial structural and inflammatory changes with exogenous progestogens. Trends in Endocrinology and Metabolism. 2008;19(5):167–74.CrossRefGoogle ScholarPubMed
Han, L, Taub, R, Jensen, JT. Cervical mucus and contraception: What we know and what we don’t. Contraception. 2017;96(5):310–21.CrossRefGoogle ScholarPubMed
Ortiz, ME, Croxatto, HB. Copper-T intrauterine device and levonorgestrel intrauterine system: Biological bases of their mechanism of action. Contraception. 2007;75(6 Suppl):S16–30.CrossRefGoogle ScholarPubMed
Erkkola, R. Recent advances in hormonal contraception. Curr Opin Obstet Gynecol. 2007;19(6):547–53.CrossRefGoogle ScholarPubMed
Baird, DT, Collins, J, Cooke, I et al. Ovarian and endometrial function during hormonal contraception. Hum Reprod. 2001;16(7)1527–35.Google Scholar
Burkman, RT. Transdermal hormonal contraception: Benefits and risks. Am J Obstet Gynecol. 2007;197(2):134.e1–6.CrossRefGoogle ScholarPubMed
Brache, V, Faundes, A. Contraceptive vaginal rings: A review. Contraception. 2010;82(5):418–27.CrossRefGoogle ScholarPubMed
Sitruk-Ware, R, Nath, A. The use of newer progestins for contraception. Contraception. 2010;82(5):410–17.CrossRefGoogle ScholarPubMed
Jacobstein, R, Polis, CB. Progestin-only contraception: Injectables and implants. Best Pract Res Clin Obstet Gynaecol. 2014;28(6):795–806.CrossRefGoogle ScholarPubMed
Apter, D, Gemzell-Danielsson, K, Hauck, B, Rosen, K, Zurth, C. Pharmacokinetics of two low-dose levonorgestrel-releasing intrauterine systems and effects on ovulation rate and cervical function: Pooled analyses of phase II and III studies. Fertil Steril. 2014;101(6):1656–62.CrossRefGoogle ScholarPubMed
Wagenfeld, A, Saunders, PTK, Whitaker, L, Critchley, HOD. Selective progesterone receptor modulators (SPRMs): Progesterone receptor action, mode of action on the endometrium and treatment options in gynecological therapies. Expert Opin Ther Targets. 2016;20(9):1045–54.CrossRefGoogle ScholarPubMed
Jadav, SP, Parmar, DM. Ulipristal acetate: A progesterone receptor modulator for emergency contraception. J Pharmacol aPharmacother. 2012;3(2):109–11.Google ScholarPubMed
Araû, VR, Gastal, MO, Figueiredo, JR, Gastal, EL. In vitro culture of bovine prenatal follicles: A review. Reprod. Biol. Endocrinol. 2014;12:78. https://doi.org/10.1186/1477-7827-12-78.Google Scholar
Andersen, AN, Ernst, E, 2011. Gynækologisk Endokrinologi. In Ottesen, B, Mogensen, O, Forman, A (eds.), Gynækologi. 4th edition. Copenhagen: Munksgaard Danmark, 2011.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×