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Chapter 22 - Contraception in Women with Cardiovascular Conditions

from Section 2A - Sexual and Reproductive Healthcare: Contraception

Published online by Cambridge University Press:  16 January 2024

By
Angelo Cagnacci ,
Claudia Massarotti ,
Laura Gabbi  and
Anjeza Xholli
Edited by
Johannes Bitzer  and
Tahir A. Mahmood
Johannes Bitzer
Affiliation:
University Women's Hospital, Basel
Tahir A. Mahmood
Affiliation:
Victoria Hospital, Kirkcaldy
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Summary

Cardiovascular conditions include arterial disease, mainly myocardial infarction, ischemic stroke, peripheral artery disease, and venous thromboembolism (VTE). A combination of multiple risk factors or evidence of microvascular diseases can be considered as risky as a cardiovascular event.

Type
Chapter
Information
Textbook of Contraception, Sexual and Reproductive Health , pp. 154 - 158
Publisher: Cambridge University Press
Print publication year: 2024

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References

Yusuf, S, Hawken, S, Ounpuu, S et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study. Lancet. 2004;364(9438):937–52.CrossRefGoogle ScholarPubMed
O’Donnell, MJ, Xavier, D, Liu, L et al. Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): A case-control study. Lancet. 2010;376(9735):112–23.Google ScholarPubMed
Hannaford, PC, Croft, PR, Kay, CR. Oral contraception and stroke: Evidence from the Royal College of General Practitioners’ Oral Contraception Study. Stroke. 1994;25:935–42.CrossRefGoogle ScholarPubMed
Poulter, NR for the WHO Collaborative Study of Cardiovascular Disease and Steroid Hormone Contraception. Ischaemic stroke and combined oral contraceptives: Results of an international, multicentre, case-control study. Lancet. 1996;348:498–505.Google Scholar
Weill, A, Dalichampt, M, Raguideau, F et al. Low dose oestrogen combined oral contraception and risk of pulmonary embolism, stroke, and myocardial infarction in five million French women: Cohort study. BMJ. 2016;353:i2002.CrossRefGoogle ScholarPubMed
Roach, RE, Helmerhorst, FM, Lijfering, WM et al. Combined oral contraceptives: The risk of myocardial infarction and ischemic stroke. Cochrane Database Syst Rev. 2015;8:CD011054.Google Scholar
Lidegaard, Ø, Kreiner, S. Contraceptives and cerebral thrombosis: A five-year national case-control study. Contraception. 2002;65:197–205.CrossRefGoogle ScholarPubMed
Lidegaard, Ø, Løkkegaard, E, Jensen, A, Skovlund, CW, Keiding, N. Thrombotic stroke and myocardial infarction with hormonal contraception. N Engl J Med. 2012;366(24):2257–66.CrossRefGoogle ScholarPubMed
Dinger, J, Mohner, S, Heinemann, K. Cardiovascular risks associated with the use of drospirenone-containing combined oral contraceptives. Contraception. 2016;93:378–85.CrossRefGoogle ScholarPubMed
Dinger, J, Mohner, S, Heinemann, K. Combined oral contraceptives containing dienogest and estradiol valerate may carry a lower risk of venous and arterial thromboembolism compared to conventional preparations: Results from the extended INAS-SCORE study. Front Women’s Health. 2020; 5:1–8.CrossRefGoogle Scholar
World Health Organization. Medical eligibility criteria for contraceptive use. 5th edition. Geneva: World Health Organization, 2015. www.who.int/publications/i/item/9789241549158.Google Scholar
Ezihe-Ejifor, JA, Hutchinson, N. Anticlotting mechanisms I: Physiology and pathology. Contin Educ Anaesth Crit Care Pain. 2013;13:87–92.CrossRefGoogle Scholar
Cagnacci, A. Hormonal contraception: Venous and arterial disease. EJCRHC. 2017;22:191–9.Google ScholarPubMed
Rosendaal, FR, Van Hylckama Vlieg, A, Tanis, BC, Helmerhorst, FM. Estrogens, progestogens and thrombosis. J Thromb Haemost. 2003;1:1371–80.CrossRefGoogle ScholarPubMed
Pisoni, CN, Cuadrado, MJ, Khamashta, MA, Hunt, BJ. Treatment of menorrhagia associated with oral anticoagulation: Efficacy and safety of the levonorgestrel releasing intrauterine device (Mirena coil). Lupus. 2006;15:877–80.CrossRefGoogle ScholarPubMed
Kilic, S, Yuksel, B, Doganay, M et al. The effect of levonorgestrel-releasing intrauterine device on menorrhagia in women taking anticoagulant medication after cardiac valve replacement. Contraception. 2009;80:152–7.CrossRefGoogle ScholarPubMed
Faculty of Sexual & Reproductive Healthcare. UK medical eligibility use. UKMEK 2016 (amended September 2019).Google Scholar
Roach, RE, Lijfering, WM, Van Hylckama Vlieg, A et al. The risk of venous thrombosis in individuals with a history of superficial vein thrombosis and acquired venous thrombotic risk factors. Blood. 2013;122:4264–9.CrossRefGoogle ScholarPubMed
De Bastos, M, Stegeman, BH, Rosendaal, FR et al. Combined oral contraceptives: Venous thrombosis. Cochrane Database Syst Rev. 2014;CD010813.CrossRefGoogle Scholar
Reich, LM, Bower, M, Key, NS. Role of the geneticist in testing and counseling for inherited thrombophilia. Genet Med. 2003;5:133–43.CrossRefGoogle ScholarPubMed
Fruzzetti, F, Cagnacci, A. Venous thrombosis and hormonal contraception: What’s new with estradiol-based hormonal contraceptives? Open Access J Contracept. 2018;9:75–9.CrossRefGoogle ScholarPubMed
Prandoni, P, Prins, MH, Ghirarduzzi, A et al. Family history of venous thrombosis or sudden death as a risk factor for venous thromboembolism. Thromb Haemost. 2012;107:1191–2.Google ScholarPubMed
Oger, E. Incidence of venous thromboembolism: A community-based study in Western France. EPI-GETBP Study Group. Groupe d’Etude de la Thrombose de Bretagne Occidentale. Thromb Haemost. 2000;83:657–60.Google Scholar
Sugiura, K, Ojima, T, Urano, T, Kobayashi, T. The incidence and prognosis of thromboembolism associated with oral contraceptives: Age-dependent difference in Japanese population. J Obstet Gynaecol Res. 2018;44:1766–72.CrossRefGoogle ScholarPubMed
Parkin, L, Sweetland, S, Balkwill, A et al. Body mass index, surgery, and risk of venous thromboembolism in middle-aged women: A cohort study. Circulation. 2012;125:1897–1904.CrossRefGoogle ScholarPubMed
Horton, LG, Simmons, KB, Curtis, KM. Combined hormonal contraceptive use among obese women and risk for cardiovascular events: A systematic review. Contraception. 2016;94:590–604.CrossRefGoogle ScholarPubMed
Merki-Feld, GS, Skouby, S, Serfaty, D et al. European society of contraception statement on contraception in obese women. Eur J Contracept Reprod Health Care. 2015;20:19–28.CrossRefGoogle ScholarPubMed
Cagnacci, A, Ferrari, S, Napolitano, A et al. Combined oral contraceptive containing drospirenone does not modify 24-h ambulatory blood pressure but increases heart rate in healthy young women: Prospective study. Contraception. 2013;88:413–17.Google Scholar
Grandi, G, Napolitano, A, Cagnacci, A. Metabolic impact of combined hormonal contraceptives containing estradiol. Expert Opin Drug Metab Toxicol. 2016;12:779–87.CrossRefGoogle ScholarPubMed
Sánchez-Guerrero, J, Uribe, AG, Jiménez-Santana, L et al. A trial of contraceptive methods in women with systemic lupus erythematosus. N Engl J Med. 2005;353:2539–49.CrossRefGoogle ScholarPubMed
Etminan, M, Takkouche, B, Isorna, FC, Samii, A. Risk of ischaemic stroke in people with migraine: Systematic review and meta-analysis of observational studies. BMJ. 2005;8:330(7482):63.Erratum in: BMJ. 2005;330(7487):345.Erratum in: BMJ. 2005;330(7491):596.CrossRefGoogle Scholar
Edlow, AG, Bartz, D. Hormonal contraceptive options for women with headache: A review of the evidence. Rev Obstet Gynecol. 2010;3:55–65.Google ScholarPubMed

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