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Section 2 - Physiology

Published online by Cambridge University Press:  19 June 2018

Arun Gupta
Addenbrooke’s Hospital, Cambridge
Adrian Gelb
University of Cambridge San Francisco/University of California, San Francisco
Derek Duane
Addenbrooke’s Hospital, Cambridge
Ram Adapa
Addenbrooke’s Hospital, Cambridge
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Publisher: Cambridge University Press
Print publication year: 2018

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Further Reading

Aaslid, R., Lindegaard, K.F., Sorteberg, W., et al: Cerebral autoregulation dynamics in humans. Stroke 1989; 20(1):4552.Google Scholar
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Ter Laan, M., van Dijk, J.M.C., Elting, J.W., et al: Sympathetic regulation of cerebral blood flow in humans: A review. Br J Anaesth 2013; 111(3):361367.Google Scholar

Further Reading

Mergenthaler, P., Lindauer, U., Gerald, A.D., et al: Sugar for the brain: The role of glucose in physiological and pathological brain function. Trends Neurosci 2013; 36(10):587–597.Google Scholar
Taher, M., Leen, W.G., Wevers, R.A., Willemsen, M.A.: Lactate and its many faces. Eur J Paediatr Neurol 2016 January; 20(1):3–10.Google Scholar

Further Reading

Bratton, S.L., Chestnut, R.M., Ghajar, J., et al:Guidelines for the management of severe traumatic brain injury. VI. Indications for intracranial pressure monitoring. J Neurotrauma 2007; 24(Suppl 1):S37–S44.Google Scholar
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Further Reading

Astrup, J., Siesjo, B.K., Symon, L.: Thresholds in cerebral ischemia: The ischemic penumbra. Stroke 1981; 12:723725.Google Scholar
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Knowland, D., Arac, A., Sekiguchi, K.J., et al: Stepwise recruitment of transcellular and paracellular pathways underlies blood-brain barrier breakdown in stroke. Neuron 2014; 82:603617.Google Scholar
Polster, B.M., Fiskum, G.: Mitochondrial mechanisms of neural cell apoptosis. J Neurochem 2004; 90:12811289.Google Scholar
Prakash, R., Carmichael, S.T.: Blood-brain barrier breakdown and neovascularization processes after stroke and traumatic brain injury. Curr Opin Neurol 2015; 28:556564.Google Scholar
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Further Reading

Berkhemer, O.A., Fransen, P.S., Beumer, D., et al: A randomized trial of intraarterial treatment for acute ischemic stroke.N Engl J Med 2015; 372:1120.Google Scholar
Connolly, E.S. Jr, Rabinstein, A.A., Carhuapoma, J.R., et al: Guidelines for the management of aneurysmal subarachnoid hemorrhage. Stroke 2012; 43:17111737.Google Scholar
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Jinadasa, S., Boone, D.: Controversies in the management of traumatic brain injury. Anesthesiol Clin 2016; 34:557575.Google Scholar
Kawaguchi, M., Furuya, H., Patel, P.M.: Neuroprotective effects of anesthetic agents. J Anesth 2005; 19:150156.Google Scholar
Powers, W.J., Derdeyn, C.P., Biller, J., et al: 2015 American Heart Association/American Stroke Association focused update of the 2013 guidelines for the early management of patients with acute ischemic stroke regarding endovascular treatment. Stroke 2015; 46:30243039.Google Scholar
Quillinan, N., Herson, P.S., Traystman, R.J.: Neuropathophysiology of brain injury. Anesthesiol Clin 2016; 34:453464.Google Scholar
Steiner, T., Juvela, S., Unterberg, A., et al: European Stroke Organization guidelines for the management of intracranial aneurysms and subarachnoid haemorrhage. Cerebrovasc Dis 2013; 35:93112.Google Scholar
Todd, M.M., Hindman, B.J., Clarke, W.R., Torner, J.C.: Mild intraoperative hypothermia during surgery for intracranial aneurysm. N Engl J Med 2005; 352:135145.Google Scholar
The Brain Trauma Foundation: The American Association of Neurological Surgeons. The Joint Section on Neurotrauma and Critical Care. Hyperventilation. J Neurotrauma 2000; 17:513520.Google Scholar

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