To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure email@example.com
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Studies including patients with depression in the course of bipolar disorder I or II indicate lithium's effectiveness in the treatment and prevention of bipolar depression. A handful of studies have focused on the use of antidepressants as maintenance treatment for bipolar patients. Long-standing concerns that antidepressant treatment of bipolar depression may induce a switch to mania, an onset of rapid cycling, or treatment resistance. This chapter lists out various antidepressants that include quetiapine, lamotrigine, olanzapine/fluoxetine, aripiprazole, ziprasidone, risperidone, carbamazepine and valproate. The other treatments for bipolar depression include electroconvulsive therapy, deep brain stimulation and transcranial magnetic stimulation. As a secondary strategy, based on existing data, it seems reasonable to use antidepressants in combination with a mood stabilizer, with attention paid to possible emergence of manic/hypomanic symptoms. Despite widespread usage, the efficacy of lamotrigine for either acute or maintenance treatment of bipolar depression remains in question.