José Celestino Mutis, physician, naturalist and educator, and a native of the port of Cádiz in Spain, arrived at the Spanish viceroyalty of New Granada in the year 1760 as personal physician to Viceroy Messía de la Zerda. His arrival coincided with the beginning of a period of change in the cultural history of that reino or “kingdom”. Progressive reform in the colonial universities, stimulus to scientific study, new directions in philosophic and political thought and the formation of an enlightened society were the contributions don José made to the cultural partrimony of New Granada. The results of his activity in this viceroyalty were manifestations of that period in history which is termed the Enlightenment.