This paper analyzes the urban insertion of some Iranian religious minorities, focusing on three communities, all of which lived in separated neighborhoods: Armenians of Isfahan, Jews of Shiraz, and Zoroastrians of Yazd. After a discussion on the link between non-Muslims' spatial and social isolation and Iranian culture and Shiism, the paper goes on to describe the organization of these neighborhoods during the recent centuries and the recent—and contrastive—evolutions of two of them: while Zoroastrians view their quarter like a humiliating ghetto, of which they wish to go out, Armenians are proud of it, and try up till now to jealously preserve their isolation.