Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-76fb5796d-vfjqv Total loading time: 0 Render date: 2024-04-26T22:32:26.818Z Has data issue: false hasContentIssue false

27 - Management of cancer of the cervix

Published online by Cambridge University Press:  05 November 2015

By
Samantha Cox ,
Kate Parker  and
Louise Hanna
Edited by
Louise Hanna ,
Tom Crosby  and
Fergus Macbeth
Samantha Cox
Affiliation:
Velindre Cancer Centre, Velindre Hospital, Cardiff, UK
Kate Parker
Affiliation:
South West Wales Cancer Centre, Singleton Hospital, Swansea, UK
Louise Hanna
Affiliation:
Velindre Cancer Centre, Velindre Hospital, Cardiff, UK
Louise Hanna
Affiliation:
Velindre Cancer Centre, Velindre Hospital, Cardiff
Tom Crosby
Affiliation:
Velindre Cancer Centre, Velindre Hospital, Cardiff
Fergus Macbeth
Affiliation:
Velindre Cancer Centre, Velindre Hospital, Cardiff
Get access

Summary

A summary is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Chapter
Information
Practical Clinical Oncology , pp. 374 - 386
Publisher: Cambridge University Press
Print publication year: 2015

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Andreyev, H. J., Benton, B., Lalji, A., et al. (2013). Algorithm-based management of patients with gastrointestinal symptoms in patients after pelvic radiation treatment (ORBIT): a randomised controlled trial. Lancet, 382, 2084–2092.CrossRefGoogle ScholarPubMed
Bader, A., Winter, R., Haas, J., et al. (2007). Where to look for the sentinel lymph node in cervical cancer. Am. J. Obstet. Gynecol., 197, 678.CrossRefGoogle ScholarPubMed
Boon, M. E., de Graaff Guilloud, J. C., et al. (1987). Efficacy of screening for cervical squamous and adenocarcinoma: the Dutch experience. Cancer, 59, 862–866.3.0.CO;2-P>CrossRefGoogle ScholarPubMed
Buckley, S. L., Tritz, D. M., Van Le, L., et al. (1996). Lymph node metastases and prognosis in patients with stage IA2 cervical cancer. Gynecol. Oncol., 63, 4–9.CrossRefGoogle ScholarPubMed
Denton, A. S., Bond, S. J., Matthews, S., et al. (2000). National audit of the management and outcome of carcinoma of the cervix treated with radiotherapy in 1993. Clin. Oncol. (R. Coll. Radiol.), 12, 347–353.CrossRefGoogle Scholar
Denton, K. J., Herbert, A., Turnbull, L. S., et al. (2008). The revised BSCC terminology for abnormal cervical cytology. Cytopathology, 19, 137–157.Google ScholarPubMed
Ferlay, J., Bray, F., Pisani, P., et al. (2004). GLOBOCAN 2002. Cancer Incidence, Mortality and Prevalence Worldwide. IARC Cancer Base No. 5, Version 2.0. Lyon: IARC Press.Google Scholar
Green, J. A., Kirwan, J. M., Tierney, J. F., et al. (2001). Survival and recurrence after concomitant chemotherapy and radiotherapy for cancer of the uterine cervix: a systematic review and meta-analysis. Lancet, 358, 781–786.CrossRefGoogle ScholarPubMed
Haie-Meder, C., Pötter, R., Van Limbergen, E., et al. (2005). Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (I): concepts and terms in 3D image based treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV.Radiother. Oncol., 74, 235–245.CrossRefGoogle Scholar
Helmerhorst, T. J. and Meijer, C. J. (2002). Cervical cancer should be considered as a rare complication of oncogenic HPV infection rather than a STD.Int. J. Gynecol. Cancer, 12, 235–236.CrossRefGoogle ScholarPubMed
ICRU. (1985). Dose and Volume Specification for Intra-cavitary Therapy in Gynaecology. Report no. 38. Bethesda, MD: International Commission on Radiological Units and Measurements.
International Union Against Cancer. (1995). Prognostic Factors in Cancer, ed. Hermanek, P., Gospodarowicz, M. K., Henson, D. E., et al.Berlin: Springer-Verlag.CrossRef
Jadon, R., Pembroke, C. A., Hanna, C. L., et al. (2014). A systematic review of organ motion and image-guided strategies in external beam radiotherapy for cervical cancer. Clin. Oncol. (R. Coll. Radiol.), 26, 185–196.CrossRefGoogle ScholarPubMed
Keys, H. M., Bundy, B. N. and Stehman, F. B. (1999). Cisplatin, radiation and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage 1B cervical carcinoma. N. Engl. J. Med., 340, 1154–1161.CrossRefGoogle Scholar
Kelly, R. S., Patnick, J., Kitchener, H. C., et al. (2011). HPV testing as a triage for borderline or mild dyskaryosis on cervical cytology: results from the Sentinel Sites study. Br. J. Cancer, 105, 983–988.CrossRefGoogle ScholarPubMed
Lehtinen, M. and Dillner, J. (2013). Clinical trials of human papillomavirus vaccines and beyond. Nat. Rev. Clin. Oncol., 10, 400–410.CrossRefGoogle ScholarPubMed
Loiselle, C. and Koh, W. (2010). The emerging use of IMRT for treatment of cervical cancer. J. Natl Compr. Canc. Netw., 8, 1425–1434.CrossRefGoogle ScholarPubMed
Lukka, H., Hirte, H., Fyles, A., et al. (2002). Concurrent cisplatin-based chemotherapy plus radiotherapy for cervical cancer – a meta-analysis. Clin. Oncol. (R. Coll. Radiolol.), 14, 203–212.Google ScholarPubMed
Monk, B. J. and Montz, F. J. (1992). Invasive cervical cancer complicating intrauterine pregnancy: treatment with radical hysterectomy. Obstet. Gynecol., 80, 199–203.Google ScholarPubMed
Moreno, V., Bosch, F. X., Munoz, N., et al. (2002). Effect of oral contraceptives on risk of cervical cancer in women with human papillomavirus infection: the IARC multicentric case-control study. Lancet, 359, 1085–1092.CrossRefGoogle ScholarPubMed
Morris, M., Eifel, P., Lu, J., et al. (1999). Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer. N. Engl. J. Med., 340, 1137–1143.CrossRefGoogle ScholarPubMed
Nag, S., Erickson, B., Thomadsen, B., et al. (2000). The American Brachytherapy Society recommendations for high-dose-rate brachytherapy for carcinoma of the cervix. Int. J. Radiat. Oncol. Biol. Phys., 48, 201–211.Google ScholarPubMed
Nesvacil, N., Pötter, R., Sturdza, A., et al. (2012). Adaptive imaged guided brachytherapy for cervical cancer: a combined MRI-/CT-planning technique with MRI only at first fraction. Radiother. Oncol., 107, 75–81.Google Scholar
NHS Cancer Screening Programme. (2010). Colposcopy and Programme Management for the NHS Cervical Screening Programme 2nd Edition. NHSCP publication no. 20. Sheffield: NHS Cancer Screening Programmes.
NICE. (2003). Guidance on the Use of Liquid-Based Cytology for Cervical Screening, Technology Appraisal no. 69. London: National Institute for Clinical Excellence.
NICE. (2006). High Dose Rate Brachytherapy for Carcinoma of the Cervix. Interventional Procedure Guidance 160. London: National Institute for Clinical Excellence.
NICE. (2015). Suspected cancer: recognition and referral. NICE guideline. London: National Institute for Health and Care Excellence.
Percorelli, S. (2009). Revised FIGO staging for carcinoma of the vulva, cervix and endometrium. Int. J. Gynaecol. Obstet., 105, 103–104.Google Scholar
Peters, W. A. 3rd, Liu, P. Y., Barrett, R. J. 2nd, et al. (2000). Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix. J. Clin. Oncol., 18, 1606–1613.CrossRefGoogle ScholarPubMed
Pötter, R., Haie-Meder, C., Van Limbergen, E., et al. (2006). Recommendations from GYN ESTRO working group (II): concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy – 3D dose volume parameters and aspects of 3D imaged-based anatomy, radiation physics, radiobiology. Radiother. Oncol., 78, 67–77.CrossRefGoogle Scholar
Pötter, R., Kirisits, C., Fidarova, E.et al. (2008). Present status and future of high-precision image guided adaptive brachytherapy for cervix cancer. Acta Oncol., 47, 1325–1336.CrossRefGoogle Scholar
Pötter, R., Georg, P., Dimopoulos, J., et al. (2011). Clinical outcome of protocol based image (MRI) guided adaptive brachytherapy combined with 3D conformal radiotherapy with or without chemotherapy in patients with locally advanced cervical cancer. Radiother. Oncol., 100, 116–123.CrossRefGoogle ScholarPubMed
RCP and RCR. (2013). Evidence-based indications for the use of PET-CT in the UK. London: Royal College of Physicians and Royal College of Radiologists.
RCR. (2008). The Timely Delivery of Radical Radiotherapy: Standards and Guidelines for the Management of Unscheduled Treatment Interruptions, Third Edition, 2008. London: The Royal College of Radiologists.
RCR. (2009). Implenting Image-guided Brachytherapy for Cervix Cancer in the UK. London: Royal College of Radiologists.
Rogers, L., Siu, S., Luesley, D., et al. (2012). Radiotherapy and chemoradiation after surgery for early cervical cancer (Review). Cochrane Database of Systematic Reviews, Issue 5. Art. No.: CD007583.CrossRefGoogle Scholar
Rose, P. G., Bundy, B. N., Watkins, E. B., et al. (1999). Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer. N. Engl. J. Med., 340, 1144–1153.CrossRefGoogle ScholarPubMed
Sevin, B. U., Nadji, M., Averette, H. E., et al. (1992). Microinvasive carcinoma of the cervix. Cancer, 70, 2121–2128.3.0.CO;2-S>CrossRefGoogle ScholarPubMed
Small, W., Mell, L. K., Anderson, P., et al. (2008). Consensus guidelines for the delineation of the clinical target volume for intensity modulated pelvic radiotherapy in the postoperative treatment of endometrial and cervical cancer. Int. J. Radiat. Oncol. Biol. Phys., 71(2), 428–434.CrossRefGoogle ScholarPubMed
Smith, J. S., Herrero, R., Bosetti, C., et al. (2002). Herpes simplex virus-2 as a human papillomavirus cofactor in the etiology of invasive cervical cancer. J. Natl Cancer Inst., 94, 1604–1613.CrossRefGoogle ScholarPubMed
Tan, L. T., Coles, C. E., Hart, C., et al. (2009). Clinical impact of computer tomography-based image-guided brachytherapy for cervix cancer using the tandem-ring applicator – the Addenbrooke's experience. Clin. Oncol. (R. Coll. Radiol.), 21, 175–182.CrossRefGoogle Scholar
Tewari, K. S., Sill, M., Penson, R., et al. (2014). Final overall survival analysis of the phase III randomized trial of chemotherapy with and without Bevacizumab for advanced cervical cancer: a NRG oncology–GOG study. Ann. Oncol., 25(Suppl. 4), LBA26.CrossRefGoogle Scholar
Trent Cancer Registry. (2011). Profile of Cervical Cancer in England: Incidence, Mortality and Survival. Sheffield: NHS Cancer Screening Programmes.
Wachter-Gerstner, N., Wachter, S., Reinstadler, E., et al. (2003). The impact of sectional imaging on dose escalation in endocavitary HDR-brachytherapy of cervical cancer: results of a prospective comparative trial. Radiother. Oncol., 68, 51–59.CrossRefGoogle ScholarPubMed
Whitney, C. W., Sause, W., Bundy, B. N., et al. (1999). Randomised comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage IIB/IVA carcinoma of the cervix with negative para-aortic lymph nodes: a Gynecologic Oncology and South West Oncology Group Study. J. Clin. Oncol., 17, 1339–1348.CrossRefGoogle Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×