Book contents
- Frontmatter
- Contents
- Preface
- Acknowledgments
- Chapter 1 Life Forms and Their Origins
- Chapter 2 Nucleic Acids
- Chapter 3 Proteins
- Chapter 4 Simple Chromosomes
- Chapter 5 Chromosomes of Eukarya
- Chapter 6 Genome Content
- Chapter 7 RNA Synthesis 1: Transcription
- Chapter 8 RNA Synthesis 2: Processing
- Chapter 9 Abundance of RNAs in Bacteria
- Chapter 10 Abundance of RNAs in Eukarya
- Chapter 11 Protein Synthesis
- Chapter 12 DNA Replication
- Chapter 13 Chromosome Replication
- Chapter 14 Molecular Events of Recombination
- Chapter 15 Micromutations
- Chapter 16 Repair of Altered DNA
- Chapter 17 Reproduction of Bacteria
- Chapter 18 Horizontal Gene Transfer in Bacteria
- Chapter 19 Cell Cycles of Eukarya
- Chapter 20 Meiosis
- Chapter 21 Chromosomal Abnormalities
- Chapter 22 Life Cycles of Eukarya
- Chapter 23 Reproduction of Viruses
- Chapter 24 Genetic Processes in Development
- Chapter 25 Sex Determination and Dosage Compensation
- Chapter 26 Cancer
- Chapter 27 Cutting, Sorting, and Copying DNA
- Chapter 28 Genotyping by DNA Analysis
- Chapter 29 Genetically Engineered Organisms
- Chapter 30 Genomics
- Chapter 31 Behavior of Genes and Alleles
- Chapter 32 Probability and Statistics Toolkit
- Chapter 33 Genes, Environment, and Interactions
- Chapter 34 Locating Genes
- Chapter 35 Finding and Detecting Mutations
- Chapter 36 Cytoplasmic Inheritance
- Chapter 37 Genetic Variation in Populations
- Chapter 38 Mutation, Migration, and Genetic Drift
- Chapter 39 Natural Selection
- Chapter 40 Quantitative Genetics
- Chapter 41 Speciation
- Chapter 42 Molecular Evolution and Phylogeny
- Glossary
- Index
Chapter 37 - Genetic Variation in Populations
Published online by Cambridge University Press: 05 June 2012
- Frontmatter
- Contents
- Preface
- Acknowledgments
- Chapter 1 Life Forms and Their Origins
- Chapter 2 Nucleic Acids
- Chapter 3 Proteins
- Chapter 4 Simple Chromosomes
- Chapter 5 Chromosomes of Eukarya
- Chapter 6 Genome Content
- Chapter 7 RNA Synthesis 1: Transcription
- Chapter 8 RNA Synthesis 2: Processing
- Chapter 9 Abundance of RNAs in Bacteria
- Chapter 10 Abundance of RNAs in Eukarya
- Chapter 11 Protein Synthesis
- Chapter 12 DNA Replication
- Chapter 13 Chromosome Replication
- Chapter 14 Molecular Events of Recombination
- Chapter 15 Micromutations
- Chapter 16 Repair of Altered DNA
- Chapter 17 Reproduction of Bacteria
- Chapter 18 Horizontal Gene Transfer in Bacteria
- Chapter 19 Cell Cycles of Eukarya
- Chapter 20 Meiosis
- Chapter 21 Chromosomal Abnormalities
- Chapter 22 Life Cycles of Eukarya
- Chapter 23 Reproduction of Viruses
- Chapter 24 Genetic Processes in Development
- Chapter 25 Sex Determination and Dosage Compensation
- Chapter 26 Cancer
- Chapter 27 Cutting, Sorting, and Copying DNA
- Chapter 28 Genotyping by DNA Analysis
- Chapter 29 Genetically Engineered Organisms
- Chapter 30 Genomics
- Chapter 31 Behavior of Genes and Alleles
- Chapter 32 Probability and Statistics Toolkit
- Chapter 33 Genes, Environment, and Interactions
- Chapter 34 Locating Genes
- Chapter 35 Finding and Detecting Mutations
- Chapter 36 Cytoplasmic Inheritance
- Chapter 37 Genetic Variation in Populations
- Chapter 38 Mutation, Migration, and Genetic Drift
- Chapter 39 Natural Selection
- Chapter 40 Quantitative Genetics
- Chapter 41 Speciation
- Chapter 42 Molecular Evolution and Phylogeny
- Glossary
- Index
Summary
Overview
Natural populations of most plants and animals are genetically diverse, and a sizeable fraction of their genes have two or more common alleles. Population genetics is about the frequencies of alleles in populations and how these allele frequencies change from generation to generation. This chapter describes the following:
The relation between allele frequencies and genotype frequencies in populations
The magnitude of genetic variation in populations, and how it is measured
As with Mendelian theory and experiments, in population genetics one should focus attention first and foremost on gametes and haplotypes.
Populations
A population is a group of organisms of one species, living in one area. An asexual population is a clone, while a population of sexually reproducing, freely interbreeding eukarya is sometimes called a deme. In diplontic species, population size is defined as the number of all diploid individuals in that population, N. The copies of a gene in a population comprise a gene pool, and the size of the gene pool for diplontic species is 2N.
Predicting Genotype Frequencies from Allele Frequencies
Populations in Static Equilibrium
Consider gene A, an autosomal gene with two alleles, A1 and A2; the gametes in this population carry either A1 or A2. The frequency of A1 gametes is p and the frequency of A2 gametes is q, where p + q = 1.
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- Information
- Fundamental Genetics , pp. 359 - 365Publisher: Cambridge University PressPrint publication year: 2004