Skip to main content Accessibility help
×
Hostname: page-component-77c89778f8-gvh9x Total loading time: 0 Render date: 2024-07-19T10:24:56.182Z Has data issue: false hasContentIssue false

5 - Genetic engineering

from PART II - Engineering genes

Published online by Cambridge University Press:  16 March 2010

Susan Aldridge
Affiliation:
Clinical Sciences Centre, London
Get access

Summary

Knowing the structure of DNA – and how it works – has created many exciting new possibilities in the world of biotechnology (the use of biological processes to make useful products). Probably the most important technology to flow from Crick and Watson's discovery is genetic engineering.

The tools of genetic engineering allow the transfer of genes from one species to another. Because different species cannot usually breed with one another and exchange genetic material, genetic engineering opens up the prospect of creating novel species. These have the potential to widen the scope of biotechnology in ways that will have a major impact on medicine, agriculture and the environment.

For instance, the first commercial example of genetic engineering involved the transfer of the gene for human insulin to the bacterium E. coli. While humans and bacteria share a common ancestor, they can breed together only on the wilder shores of science fiction. With genetic engineering, a bacterium can acquire a human gene – and treat it as one of its own. In some ways there is nothing very new about this; every time you get a cold you acquire unwelcome viral genes, but the point about genetic engineering is having some control over the transfer process. Genetic engineering always creates an organism with a novel genome, although it usually only differs by one gene from its genetically unmodified counterpart. So an E. coli bacterium with a human insulin gene does not look remotely human, or in any other way unusual!

Sometimes the creation of a novel organism is incidental and it is the product that the organism makes which is the target of the process.

Type
Chapter
Information
The Thread of Life
The Story of Genes and Genetic Engineering
, pp. 103 - 112
Publisher: Cambridge University Press
Print publication year: 1996

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

  • Genetic engineering
  • Susan Aldridge, Clinical Sciences Centre, London
  • Book: The Thread of Life
  • Online publication: 16 March 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511661570.006
Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

  • Genetic engineering
  • Susan Aldridge, Clinical Sciences Centre, London
  • Book: The Thread of Life
  • Online publication: 16 March 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511661570.006
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Genetic engineering
  • Susan Aldridge, Clinical Sciences Centre, London
  • Book: The Thread of Life
  • Online publication: 16 March 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511661570.006
Available formats
×