Skip to main content Accessibility help
×
Hostname: page-component-76fb5796d-22dnz Total loading time: 0 Render date: 2024-04-28T06:51:42.034Z Has data issue: false hasContentIssue false

13 - An empirical approach

Published online by Cambridge University Press:  01 September 2009

Søren Holm
Affiliation:
Professor, University of Oslo
Richard Ashcroft
Affiliation:
Imperial College of Science, Technology and Medicine, London
Anneke Lucassen
Affiliation:
University of Southampton
Michael Parker
Affiliation:
University of Oxford
Marian Verkerk
Affiliation:
Rijksuniversiteit Groningen, The Netherlands
Guy Widdershoven
Affiliation:
Universiteit Maastricht, Netherlands
Get access

Summary

In the analysis of most problems in bioethics, knowledge about the state of the world and our abilities to intervene in it play a significant role. Many ethical problems only emerge when our ability to intervene in the world increases, and it is often important to know in some detail what is possible and what is not. In our ethical arguments we can therefore often discern premises of two kinds: ethical premises and empirical premises.

This means that valid ethical arguments can become false if either of these two kinds of premises is false. If I, for instance, base my analysis of the ethics of communication with persons with terminal illness on the empirical premise that most people who are told that they are terminally ill will become severely depressed and will never recover from their depression, I may well reach a quite different ethical conclusion than if I base the analysis on the premise that such depression is neither widespread nor permanent.

We can further subdivide empirical premises into three groups, each answering a different kind of ethically relevant question:

  1. What is the state of the world?

  2. What are our possibilities of intervening in the world?

  3. What are the consequences of our interventions?

The first task of an empirical approach to bioethics is therefore to identify the explicit and implicit/enthymematic empirical premises in ethical arguments and try to find out whether they are supported by research findings and theories in the relevant scientific fields.

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2005

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Audrain, J., Rimer, B., Cella, D.et al. (1998). Genetic counseling and testing for breast–ovarian cancer susceptibility: what do women want?J Clin Oncol, 16(1), 133–8.CrossRefGoogle ScholarPubMed
Bartels, D. M., LeRoy, B. S., McCarthy, P. and Caplan, A. L. (1997). Nondirectiveness in genetic counseling: a survey of practitioners. Am J Med Gen, 72(2), 172–9.3.0.CO;2-X>CrossRefGoogle ScholarPubMed
Boas, F., (1925). Contributions to the Ethnology of the Kwakiutl. New York: Columbia University Press.Google Scholar
Chalmers, A. F., (1999). What is This Thing Called Science?, 3rd edn. Buckingham: Open University Press.Google Scholar
Chalmers, K. and Thomson, K. (1996). Coming to terms with the risk of breast cancer: perceptions of women with primary relatives with breast cancer. Qualitat Health Res, 6, 256–82.CrossRefGoogle Scholar
Chalmers, K., Thomson, K. and Degner, L. F. (1996). Information, support and communication needs of women with a family history of breast cancer. Cancer Nursing, 19, 204–13.CrossRefGoogle ScholarPubMed
Charmaz, K., (2000). Experiencing chronic illness. In Albrecht, G. L., Fitzpatrick, R. and Scrimshaw, S. C., eds., The Handbook of Social Studies in Health and Medicine. London: Sage, 277–92.CrossRefGoogle Scholar
Eeles, R. A. (2000). Future possibilities in the prevention of breast cancer: intervention strategies in BRCA1 and BRCA2 mutation carriers. Breast Cancer Res, 2(4), 283–90.CrossRefGoogle ScholarPubMed
Eeles, R. A., and Powles, T. J. (2000). Chemoprevention options for BRCA1 and BRCA2 mutation carriers. J Clin Oncol, 18(21Suppl.); 93S–99S.Google ScholarPubMed
Genetic testings for Cancer: The surgeon's critical role. (1999). J Am Coll Surg 188(1), 74–93. This comprises the following consecutive articles: Vogelstien, B. Familial colon cancer. 74–9; Weber, B. L. Familial breast cancer. 79–86; Greely, H. T. Ethical and legal issues associated with genetic testing. 86–9; and Peterson, G. Clinical cancer genetics 1998 (what's available to you in your practice). 89–93.CrossRef
Goffman, E., (1963). Stigma. Englewood Cliffs, New Jersey: Prentice Hall.Google Scholar
Hallowell, N., Murton, F., Statham, H., Green, J. M. and Richards, M. P. M. (1997). Women's need for information before attending genetic counselling for familial breast or ovarian cancer: a questionnaire, interview, and observational study. BMJ, 314(7076), 281–3.CrossRefGoogle ScholarPubMed
Hofferbert, S., Worringen, U., Backe, J., et al. (2000). Simultaneous interdisciplinary counseling in German breast/ovarian cancer families: first experience with patient perceptions, surveillance behavior and acceptance of genetic testing. Genetic Counseling, 11(2), 127–46.Google ScholarPubMed
Holm, S., (1997). Ethical Problems in Clinical Practice: The Ethical Reasoning of Health Care Professionals. Manchester: Manchester University Press.Google Scholar
Lodder, L. N., Frets, P. G., Trijsburg, R. W.et al. (1999). Presymptomatic testing for BRCA1 and BRCA2: how distressing are the pre-test weeks?J Med Gen, 36(12), 906–13.Google ScholarPubMed
Malinowski, B., (1922). Argonauts of the Western Pacific: An Account of Native Enterprise and Adventure in the Archipelagoes of Melanesian New Guinea. London: Routledge.Google Scholar
Marteau, T. M., Drake, H. and Bobrow, M. (1994). Counselling following diagnosis of fetal abnormality: the differing approaches of obstetricians, clinical geneticists, and genetic nurses. J Med Gen, 31(11), 864–7.CrossRefGoogle ScholarPubMed
Mauss, M., (1954). The Gift. Forms and Functions of Exchange in Archaic Societies. London: Cohen & West. [Originally Published in French 1923–4.]Google Scholar
McAllister, M. F., Evans, D. G. R., Ormiston, W., and Daly, P. (1998). Men in breast cancer families: a preliminary study of awareness and experience. J Med Gen, 35(9), 739–44.CrossRefGoogle ScholarPubMed
Michie, S. and Marteau, T. M. (1996). Predictive genetic testing in children: the need for psychological research. Br J Health Psychol, 1, 3–14.CrossRefGoogle Scholar
Michie, S., Bron, F., Bobrow, M. and Marteau, T. M. (1997). Nondirectiveness in genetics counseling: an empirical study. Am J Human Gen, 60(1), 40–7.Google ScholarPubMed
Morrow, M. and Gradishar, W. (2002). Recent developments: breast cancer. BMJ, 324, 410–14.CrossRefGoogle Scholar
Phillips, K. A., Andrulis, I. L. and Goodwin, P. J. (1999). Breast carcinomas arising in carriers of mutations in BRCA1 or BRCA2: are they prognostically different?J Clin Oncol, 17(11), 3653–63.CrossRefGoogle ScholarPubMed
Rees, C. E. and Bath, P. A. (2000). The information needs and source preferences of women with breast cancer and their family members: a review of the literature published between 1988 and 1998. J Adv Nursing, 31(4), 833–41.CrossRefGoogle ScholarPubMed
Reichelt, J. G., Dahl, A. A., Heimdal, K. and Møller, P. (1999). Uptake of genetic testing and pre-test levels of mental distress in Norwegian families with known BRCA1 mutations. Dis Markers, 15(1–3), 139–43.CrossRefGoogle ScholarPubMed
Richards, M., (1996). Families, kinship and genetics. In Marteau, T. and Richards, M., eds., The Troubled Helix: Social and Psychological Implications of the New Human Genetics. Cambridge: Cambridge University Press, 249–73.CrossRefGoogle Scholar
Sagi, M., Meiner, V., Reshef, N., Dagan, J. and Zlotogora, J. (2001). Prenatal diagnosis of sex chromosome aneuploidy: possible reasons for high rates of pregnancy termination. Prenatal Diag, 21(6), 461–5.CrossRefGoogle ScholarPubMed
Stacey, M., (1996). The new genetics: a feminist view. In Marteau, T. and Richards, M., eds., The Troubled Helix: Social and Psychological Implications of the New Human Genetics. Cambridge: Cambridge University Press, 331–49.CrossRefGoogle Scholar
Struewing, J. P., Hartge, P., Wacholder, S.et al. (1997). The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews. N Engl J Med, 336, 1401–7.CrossRefGoogle ScholarPubMed
Tercyak, K. P., Hughes, C., Main, D., et al. (2001). Parental communication of BRCA1/2 genetic test results to children. Patient Ed Counsel, 42, 213–24.CrossRefGoogle Scholar
Tobias, D. H., Eng, C., McCurdy, L. D.et al. (2000). Founder BRCA1 and 2 mutations among a consecutive series of Ashkenazi Jewish ovarian cancer patients. Gynecol Oncol, 78(2), 148–51.CrossRefGoogle ScholarPubMed
Wert, G. (1998). Ethics of predictive DNA testing for hereditary breast and ovarian cancer. Patient Ed Counsel, 35: 43–52.CrossRefGoogle ScholarPubMed
Wong, C., DiCioccio, R. A., Allen, H. J., Werness, B. A. and Piver, M. S. (1998). Mutations in BRCA1 from fixed, paraffin-embedded tissue can be artifacts of preservation. Cancer Gen Cytogen, 107(1), 21–7.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×