Book contents
- Frontmatter
- Contents
- Preface
- CHAPTER ONE CELL LINEAGE VS. INTERCELLULAR SIGNALING
- CHAPTER TWO THE BRISTLE
- CHAPTER THREE BRISTLE PATTERNS
- CHAPTER FOUR ORIGIN AND GROWTH OF DISCS
- CHAPTER FIVE THE LEG DISC
- CHAPTER SIX THE WING DISC
- CHAPTER SEVEN THE EYE DISC
- CHAPTER EIGHT HOMEOSIS
- EPILOGUE
- APPENDIX ONE Glossary of Protein Domains
- APPENDIX TWO Inventory of Models, Mysteries, Devices, and Epiphanies
- APPENDIX THREE Genes That Can Alter Cell Fates Within the (5-Cell) Mechanosensory Bristle Organ
- APPENDIX FOUR Genes That Can Transform One Type of Bristle Into Another or Into a Different Type of Sense Organ
- APPENDIX FIVE Genes That Can Alter Bristle Number by Directly Affecting SOP Equivalence Groups or Inhibitory Fields
- APPENDIX SIX Signal Transduction Pathways: Hedgehog, Decapentaplegic, and Wingless
- APPENDIX SEVEN Commentaries on the Pithier Figures
- References
- Index
APPENDIX FOUR - Genes That Can Transform One Type of Bristle Into Another or Into a Different Type of Sense Organ
Published online by Cambridge University Press: 03 December 2009
- Frontmatter
- Contents
- Preface
- CHAPTER ONE CELL LINEAGE VS. INTERCELLULAR SIGNALING
- CHAPTER TWO THE BRISTLE
- CHAPTER THREE BRISTLE PATTERNS
- CHAPTER FOUR ORIGIN AND GROWTH OF DISCS
- CHAPTER FIVE THE LEG DISC
- CHAPTER SIX THE WING DISC
- CHAPTER SEVEN THE EYE DISC
- CHAPTER EIGHT HOMEOSIS
- EPILOGUE
- APPENDIX ONE Glossary of Protein Domains
- APPENDIX TWO Inventory of Models, Mysteries, Devices, and Epiphanies
- APPENDIX THREE Genes That Can Alter Cell Fates Within the (5-Cell) Mechanosensory Bristle Organ
- APPENDIX FOUR Genes That Can Transform One Type of Bristle Into Another or Into a Different Type of Sense Organ
- APPENDIX FIVE Genes That Can Alter Bristle Number by Directly Affecting SOP Equivalence Groups or Inhibitory Fields
- APPENDIX SIX Signal Transduction Pathways: Hedgehog, Decapentaplegic, and Wingless
- APPENDIX SEVEN Commentaries on the Pithier Figures
- References
- Index
Summary
In parentheses after each gene name are the salivary gland map location and the origin of the name. The PHENOTYPES section only lists bristle-related phenotypes (see Fig. 2.8). The PROTEIN section presents available data on function, length, subcellular location, domains, and binding partners. For further information, see FlyBase and The Interactive Fly.
Abbreviations: CS (chemosensory), DS (downstream in causation; “+” activated or “–” inhibited by US gene), GOF (gain of function), LOF (partial loss of function), MS (mechanosensory), US (upstream). Evidence for the hierarchical order of genes in a pathway (US or DS) is given from a DS perspective only. Protein domains are defined in Appendix 1. Numbers of repeats (e.g., “6x”) are in parentheses. Other genes whose embryonic mutant phenotypes suggest that they may belong to this group are BarH1 and BarH2. Certain sensilla campaniformia on the wing are transformed to bristles by ash2 (a member of the Trithorax Group of regulators; cf. Ch. 8).
absent solo-MD neurons and olfactory sensilla (amos, 36F; “MD” stands for multiple dendritic). Pathway: DS(+) of lozenge; interacts positively (dosedependent) with daughterless. PHENOTYPES: Null: unknown. LOF: fewer sensilla basiconica and trichodea on the antenna. GOF: extra sensilla basiconica, trichodea, and coeloconica on the antenna, ectopic olfactory sensilla elsewhere, and conversions of bristles into olfactory sensilla. PROTEIN: Function: transcription factor (198 a.a.). Location: unknown (presumably nuclear). Domains: bHLH (C-terminal).
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- Imaginal DiscsThe Genetic and Cellular Logic of Pattern Formation, pp. 276 - 277Publisher: Cambridge University PressPrint publication year: 2002