Book contents
- Seminars in Clinical Psychopharmacology
- College Seminars Series
- Seminars in Clinical Psychopharmacology
- Copyright page
- Contents
- Contributors
- Foreword
- Preface
- Editor’s Note on Nomenclature
- Neuroscience-Based Nomenclature Glossary
- Abbreviations
- Part 1 Basic Science and General Principles
- Chapter 1 A Brief History of Psychopharmacology
- Chapter 2 Psychiatric Drug Discovery and Development
- Chapter 3 Neurotransmission and Mechanisms of Drug Action
- Chapter 4 Pharmacodynamics and Pharmacokinetics
- Chapter 5 Pharmacogenomics and Psychopharmacology
- Chapter 6 Good Clinical Practice in Psychopharmacology
- Part 2 Psychopharmacology of the Main Psychotropic Drug Groups
- Part 3 Specific Therapeutic Areas
- Index
- References
Chapter 2 - Psychiatric Drug Discovery and Development
from Part 1 - Basic Science and General Principles
Published online by Cambridge University Press: 29 May 2020
- Seminars in Clinical Psychopharmacology
- College Seminars Series
- Seminars in Clinical Psychopharmacology
- Copyright page
- Contents
- Contributors
- Foreword
- Preface
- Editor’s Note on Nomenclature
- Neuroscience-Based Nomenclature Glossary
- Abbreviations
- Part 1 Basic Science and General Principles
- Chapter 1 A Brief History of Psychopharmacology
- Chapter 2 Psychiatric Drug Discovery and Development
- Chapter 3 Neurotransmission and Mechanisms of Drug Action
- Chapter 4 Pharmacodynamics and Pharmacokinetics
- Chapter 5 Pharmacogenomics and Psychopharmacology
- Chapter 6 Good Clinical Practice in Psychopharmacology
- Part 2 Psychopharmacology of the Main Psychotropic Drug Groups
- Part 3 Specific Therapeutic Areas
- Index
- References
Summary
This chapter reviews the process of psychiatric drug discovery and development. People suffering from mental illness need better drugs with improved efficacy and reduced side-effect burden than those currently available. The aim of drug discovery and development in this area is to manage illness, improve quality of life, and to reduce burden on carers and on the economy. Long-term disability associated with incomplete treatment response profoundly compromises the ability of affected individuals to function properly and significantly reduces their quality of life. This in turn has societal consequences in terms of the cost burden associated with the high prevalence of psychiatric disorders. Brain disorders cost €141 billion per annum in the UK, with a total 2010 cost (in million € purchasing power parity) of psychotic disorders of €16 717 (Fineberg et al., 2013).
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- Seminars in Clinical Psychopharmacology , pp. 35 - 68Publisher: Cambridge University PressPrint publication year: 2020
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