Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-84b7d79bbc-2l2gl Total loading time: 0 Render date: 2024-07-31T04:40:15.441Z Has data issue: false hasContentIssue false

Chapter 30 - Female Fertility Preservation

Published online by Cambridge University Press:  03 June 2019

By
Nikoletta Panagiotopoulou
Edited by
Jane A. Stewart
Jane A. Stewart
Affiliation:
Newcastle Hospitals NHS Foundation Trust
Get access

Summary

Fertility preservation, which is defined by the National Center for Biotechnology Information as ‘a method of providing future reproductive opportunities before a medical treatment with known risk of loss of fertility’ (1), aims to mitigate the long-term effects of gonadotoxic treatment. Current evidence shows that timely fertility preservation counselling allows patients to better cope with the long-term effects of gonadotoxic treatment, including the potential for infertility (2). This chapter, thus, discusses the present status of fertility preservation in women and explores new developments in the field.

Type
Chapter
Information
Subfertility, Reproductive Endocrinology and Assisted Reproduction , pp. 227 - 232
Publisher: Cambridge University Press
Print publication year: 2019

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

National Center for Biotechnology Information. Fertility preservation 2012 [cited 2015 January 14]. Available from: www.ncbi.nlm.nih.gov/mesh/?term=fertility+preservation.Google Scholar
Mersereau, JE, Goodman, LR, Deal, AM, Gorman, JR, Whitcomb, BW, Su, HI. To preserve or not to preserve: how difficult is the decision about fertility preservation? Cancer. 2013;119(22):4044–50.CrossRefGoogle ScholarPubMed
NCIN. Macmillan-NCIN work plan - Segmenting the cancer population: All cancers combined, 20-year prevalence at the end of 2010, UK 2013 [cited 2015 July 7]. Available from: www.ncin.org.uk/about_ncin/segmentation.Google Scholar
Gidoni, Y, Holzer, H, Tulandi, T, Tan, SL. Fertility preservation in patients with non-oncological conditions. Reproductive Biomedicine Online. 2008;16(6):792–800.Google Scholar
Green, DM, Kawashima, T, Stovall, M, Leisenring, W, Sklar, CA, Mertens, AC, et al. Fertility of female survivors of childhood cancer: a report from the childhood cancer survivor study. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology. 2009;27(16):2677–85.Google ScholarPubMed
Wallace, WH, Thomson, AB, Kelsey, TW. The radiosensitivity of the human oocyte. Human Reproduction. 2003;18(1):117–21.Google Scholar
Wallace, WH, Thomson, AB, Saran, F, Kelsey, TW. Predicting age of ovarian failure after radiation to a field that includes the ovaries. International Journal of Radiation Oncology, Biology, Physics. 2005;62(3):738–44.Google Scholar
Meirow, D, Biederman, H, Anderson, RA, Wallace, WH. Toxicity of chemotherapy and radiation on female reproduction. Clinical Obstetrics and Gynecology. 2010;53(4):727–39.CrossRefGoogle ScholarPubMed
Wallace, WH, Shalet, SM, Crowne, EC, Morris-Jones, PH, Gattamaneni, HR. Ovarian failure following abdominal irradiation in childhood: natural history and prognosis. Clinical Oncology (Royal College of Radiologists (Great Britain)). 1989;1(2):75–9.CrossRefGoogle ScholarPubMed
Signorello, LB, Cohen, SS, Bosetti, C, Stovall, M, Kasper, CE, Weathers, RE, et al. Female survivors of childhood cancer: preterm birth and low birth weight among their children. Journal of the National Cancer Institute. 2006;98(20):1453–61.CrossRefGoogle Scholar
Critchley, HO, Wallace, WH, Shalet, SM, Mamtora, H, Higginson, J, Anderson, DC. Abdominal irradiation in childhood; the potential for pregnancy. British Journal of Obstetrics and Gynaecology. 1992;99(5):392–4.Google Scholar
Templeton, A, Morris, JK, Parslow, W. Factors that affect outcome of in-vitro fertilisation treatment. Lancet. 1996;348(9039):1402–6.CrossRefGoogle ScholarPubMed
te Velde, ER, Pearson, PL. The variability of female reproductive ageing. Human Reproduction Update. 2002;8(2):141–54.Google Scholar
Larsen, EC, Muller, J, Schmiegelow, K, Rechnitzer, C, Andersen, AN. Reduced ovarian function in long-term survivors of radiation- and chemotherapy-treated childhood cancer. The Journal of Clinical Endocrinology and Metabolism. 2003;88(11):5307–14.CrossRefGoogle ScholarPubMed
Speroff, L, Fritz, M. Clinical Gynecologic Endocrinology and Infertility. Philadelphia: Lippincott Williams & Wilkins; 2005.Google Scholar
Anderson, RA, Themmen, AP, Al-Qahtani, A, Groome, NP, Cameron, DA. The effects of chemotherapy and long-term gonadotrophin suppression on the ovarian reserve in premenopausal women with breast cancer. Human Reproduction. 2006;21(10):2583–92.CrossRefGoogle ScholarPubMed
Kelsey, TW, Wright, P, Nelson, SM, Anderson, RA, Wallace, WH. A validated model of serum anti-mullerian hormone from conception to menopause. PloS One. 2011;6(7):e22024.CrossRefGoogle ScholarPubMed
Dillon, KE, Sammel, MD, Prewitt, M, Ginsberg, JP, Walker, D, Mersereau, JE, et al. Pretreatment antimullerian hormone levels determine rate of posttherapy ovarian reserve recovery: acute changes in ovarian reserve during and after chemotherapy. Fertility and Sterility. 2013;99(2):477–83.Google Scholar
Anderson, RA, Rosendahl, M, Kelsey, TW, Cameron, DA. Pretreatment anti-Mullerian hormone predicts for loss of ovarian function after chemotherapy for early breast cancer. European Journal of Cancer. 2013;49(16):3404–11.CrossRefGoogle ScholarPubMed
National Institute for Health and Care Excellence (NICE). Fertility assessment and treatment for people with fertility problems (CG 156) 2013 [cited 2014 2 June]. Available from: http://guidance.nice.org.uk/CG156.Google Scholar
Herrero, L, Martinez, M, Garcia-Velasco, JA. Current status of human oocyte and embryo cryopreservation. Current Opinion in Obstetrics and Gynecology. 2011;23(4):245–50.Google Scholar
Bedoschi, GM, de Albuquerque, FO, Ferriani, RA, Navarro, PA. Ovarian stimulation during the luteal phase for fertility preservation of cancer patients: case reports and review of the literature. Journal of Assisted Reproduction and Genetics. 2010;27(8):491–4.CrossRefGoogle ScholarPubMed
Oktay, K, Buyuk, E, Libertella, N, Akar, M, Rosenwaks, Z. Fertility preservation in breast cancer patients: a prospective controlled comparison of ovarian stimulation with tamoxifen and letrozole for embryo cryopreservation. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology. 2005;23(19):4347–53.Google Scholar
Azim, AA, Costantini-Ferrando, M, Lostritto, K, Oktay, K. Relative potencies of anastrozole and letrozole to suppress estradiol in breast cancer patients undergoing ovarian stimulation before in vitro fertilization. The Journal of Clinical Endocrinology and Metabolism. 2007;92(6):2197–200.CrossRefGoogle ScholarPubMed
Bankowski, BJ, Lyerly, AD, Faden, RR, Wallach, EE. The social implications of embryo cryopreservation. Fertility and Sterility. 2005;84(4):823–32.CrossRefGoogle ScholarPubMed
Cobo, A, Garcia-Velasco, JA, Domingo, J, Remohi, J, Pellicer, A. Is vitrification of oocytes useful for fertility preservation for age-related fertility decline and in cancer patients? Fertility and Sterility. 2013;99(6):1485–95.Google Scholar
Edgar, DH, Gook, DA. A critical appraisal of cryopreservation (slow cooling versus vitrification) of human oocytes and embryos. Human Reproduction Update. 2012;18(5):536–54.Google Scholar
Friedler, S, Koc, O, Gidoni, Y, Raziel, A, Ron-El, R. Ovarian response to stimulation for fertility preservation in women with malignant disease: a systematic review and meta-analysis. Fertility and Sterility. 2012;97(1):125–33.Google Scholar
Barahmeh, S, Al Masri, M, Badran, O, Masarweh, M, El-Ghanem, M, Jaradat, I, et al. Ovarian transposition before pelvic irradiation: indications and functional outcome. The Journal of Obstetrics and Gynaecology Research. 2013;39(11):1533–7.Google Scholar
Bisharah, M, Tulandi, T. Laparoscopic preservation of ovarian function: an underused procedure. American Journal of Obstetrics and Gynecology. 2003;188(2):367–70.CrossRefGoogle ScholarPubMed
Morice, P, Juncker, L, Rey, A, El-Hassan, J, Haie-Meder, C, Castaigne, D. Ovarian transposition for patients with cervical carcinoma treated by radiosurgical combination. Fertility and Sterility. 2000;74(4):743–8.CrossRefGoogle ScholarPubMed
Donnez, J, Dolmans, MM, Demylle, D, Jadoul, P, Pirard, C, Squifflet, J, et al. Livebirth after orthotopic transplantation of cryopreserved ovarian tissue. Lancet. 2004;364(9443):1405–10.Google ScholarPubMed
Donnez, J, Dolmans, MM, Pellicer, A, Diaz-Garcia, C, Sanchez Serrano, M, Schmidt, KT, et al. Restoration of ovarian activity and pregnancy after transplantation of cryopreserved ovarian tissue: a review of 60 cases of reimplantation. Fertility and Sterility. 2013;99(6):1503–13.Google Scholar
Donnez, J, Jadoul, P, Squifflet, J, Van Langendonckt, A, Donnez, O, Van Eyck, AS, et al. Ovarian tissue cryopreservation and transplantation in cancer patients. Best Practice & Research: Clinical Obstetrics & Gynaecology. 2010;24(1):87–100.Google Scholar
Kim, SS. Assessment of long term endocrine function after transplantation of frozen-thawed human ovarian tissue to the heterotopic site: 10 year longitudinal follow-up study. Journal of Assisted Reproduction and Genetics. 2012;29(6):489–93.Google Scholar
Dolmans, MM, Luyckx, V, Donnez, J, Andersen, CY, Greve, T. Risk of transferring malignant cells with transplanted frozen-thawed ovarian tissue. Fertility and Sterility. 2013;99(6):1514–22.Google Scholar
Glode, LM, Robinson, J, Gould, SF. Protection from cyclophosphamide-induced testicular damage with an analogue of gonadotropin-releasing hormone. Lancet. 1981;1(8230):1132–4.Google Scholar
Blumenfeld, Z. GnRH-agonists in fertility preservation. Current Opinion In Endocrinology, Diabetes, and Obesity. 2008;15(6):523–8.Google Scholar
Del Mastro, L, Ceppi, M, Poggio, F, Bighin, C, Peccatori, F, Demeestere, I, et al. Gonadotropin-releasing hormone analogues for the prevention of chemotherapy-induced premature ovarian failure in cancer women: systematic review and meta-analysis of randomized trials. Cancer Treatment Reviews. 2014;40(5):675–83.Google Scholar
Eppig, JJ, Wigglesowrth, K, O’Brien, MJ. Comparison of embryonic developmental competence of mouse oocytes grown with and without serum. Molecular Reproduction and Development. 1992;32(1):33–40.Google Scholar
Telfer, EE, Zelinski, MB. Ovarian follicle culture: advances and challenges for human and nonhuman primates. Fertility and Sterility. 2013;99(6):1523–33.Google Scholar
Vanacker, J, Luyckx, V, Dolmans, MM, Des Rieux, A, Jaeger, J, Van Langendonckt, A, et al. Transplantation of an alginate-matrigel matrix containing isolated ovarian cells: first step in developing a biodegradable scaffold to transplant isolated preantral follicles and ovarian cells. Biomaterials. 2012;33(26):6079–85.CrossRefGoogle ScholarPubMed
Luyckx, V, Dolmans, MM, Vanacker, J, Legat, C, Fortuno Moya, C, Donnez, J, et al. A new step toward the artificial ovary: survival and proliferation of isolated murine follicles after autologous transplantation in a fibrin scaffold. Fertility and Sterility. 2014;101(4):1149–56.CrossRefGoogle Scholar
Zuckerman, S. The number of oocytes in the mouse ovary. Recent Progress in Hormone Research. 1951;6:63–108.Google Scholar
De Vos, M, Smitz, J, Woodruff, TK. Fertility preservation in women with cancer. Lancet. 2014;384(9950):1302–10.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×