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Section V - Treatment of Paediatric Dystonia

Published online by Cambridge University Press:  31 May 2018

Dirk Dressler
Affiliation:
Hannover Medical School
Eckart Altenmüller
Affiliation:
Hochschule für Musik, Theater und Medien, Hannover
Joachim K. Krauss
Affiliation:
Hannover Medical School
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Treatment of Dystonia , pp. 227 - 244
Publisher: Cambridge University Press
Print publication year: 2018

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References

References

Albright, AL, Cervi, A, Singletary, J. 1991. Intrathecal baclofen for spasticity in cerebral palsy. JAMA 265(11):14181422.CrossRefGoogle ScholarPubMed
Albright, AL, Barry, MJ, Shafton, DH, Ferson, SS. 2001. Intrathecal baclofen for generalized dystonia. Dev Med Child Neurol 43(10):652657.CrossRefGoogle ScholarPubMed
Albright, AL, Thompson, K, Carlos, S, Minnigh, MB. 2007. Cerebrospinal fluid baclofen concentrations in patients undergoing continuous intrathecal baclofen therapy. Dev Med Child Neurol 49(6):423425.CrossRefGoogle ScholarPubMed
Bonouvrie, LA, van Schie, PE, Becher, JG, van Ouwerkerk, WJ, Reeuwijk, A, Jeroen Vermeulen, R. 2011. Effects of intrathecal baclofen on daily care in children with secondary generalized dystonia: a pilot study. Eur J Paediatr Neurol 15(6):539543.CrossRefGoogle ScholarPubMed
Bonouvrie, LA, Becher, JG, Vles, JS, Boeschoten, K, Soudant, D, de Groot, V, van Ouwerkerk, WJ, Strijers, R, Foncke, E, Geytenbeek, J, van de Ven, PM, Teernstra, O, Vermeulen, RJ. 2013. Intrathecal baclofen treatment in dystonic cerebral palsy: a randomized clinical trial – the IDYS trial. BMC Pediatr 13:175.CrossRefGoogle ScholarPubMed
Boster, AL, Adair, RL, Gooch, JL, Nelson, ME, Toomer, A, Urquidez, J, Saulino, M. 2016. Best practices for intrathecal baclofen therapy: dosing and long-term management. Neuromodulation 19(6):623631.CrossRefGoogle ScholarPubMed
Chen, L, Chan, SC, Yung, WH. 2002. Rotational behavior and electrophysiological effects induced by GABA(B) receptor activation in rat globus pallidus. Neuroscience 114(2):417425.Google Scholar
Cruikshank, M, Eunson, P. 2007. Intravenous diazepam infusion in the management of planned intrathecal baclofen withdrawal. Dev Med Child Neurol 49(8):626628.CrossRefGoogle ScholarPubMed
de Louw, AJ, de Vente, J, Steinbusch, HP, Steinbusch, HW, Troost, J, Vles, JS. 2002. Baclofen inhibits ANP-mediated cyclic GMP synthesis in the rat cervical spinal cord. Neurosci Lett 321(1–2):120122.CrossRefGoogle ScholarPubMed
Dvorak, EM, McGuire, JR, Nelson, ME. 2010. Incidence and identification of intrathecal baclofen catheter malfunction. PM R 2(8):751756.CrossRefGoogle ScholarPubMed
Eliasson, AC, Krumlinde-Sundholm, L, Rosblad, B, Beckung, E, Arner, M, Ohrvall, AM, Rosenbaum, P. 2006. The manual ability classification system (MACS) for children with cerebral palsy: scale development and evidence of validity and reliability. Dev Med Child Neurol 48(7):549554.CrossRefGoogle ScholarPubMed
Groenendaal, F, van der Grond, J, de Vries, LS. 2004. Cerebral metabolism in severe neonatal hyperbilirubinemia. Pediatrics 114(1):291294.CrossRefGoogle ScholarPubMed
Hidecker, MJ, Paneth, N, Rosenbaum, PL, Kent, RD, Lillie, J, Eulenberg, JB, Chester, K Jr, Johnson, B, Michalsen, L, Evatt, M, Taylor, K. 2011. Developing and validating the communication function classification system for individuals with cerebral palsy. Dev Med Child Neurol 53(8):704710.CrossRefGoogle ScholarPubMed
Himmelmann, K, Uvebrant, P. 2014. The panorama of cerebral palsy in Sweden: XI. Changing patterns in the birth-year period 2003–2006. Acta Paediatr 103(6):618624.CrossRefGoogle ScholarPubMed
Himmelmann, K, Hagberg, G, Wiklund, LM, Eek, MN, Uvebrant, P. 2007. Dyskinetic cerebral palsy: a population-based study of children born between 1991 and 1998. Dev Med Child Neurol 49(4):246251.CrossRefGoogle ScholarPubMed
Hoving, MA, van Kranen-Mastenbroek, VH, van Raak, EP, Spincemaille, GH, Hardy, EL, Vles, JS, Dutch Study Group on Child Spasticity. 2006. Placebo controlled utility and feasibility study of the H-reflex and flexor reflex in spastic children treated with intrathecal baclofen. Clin Neurophysiol 117(7):15081517.CrossRefGoogle ScholarPubMed
Hoving, MA, van Raak, EP, Spincemaille, GH, Palmans, LJ, Sleypen, FA, Vles, JS, Dutch Study Group on Child Spasticity. 2007. Intrathecal baclofen in children with spastic cerebral palsy: a double-blind, randomized, placebo-controlled, dose-finding study. Dev Med Child Neurol 49(9):654659.CrossRefGoogle ScholarPubMed
Hoving, MA, Evers, SM, Ament, AJ, van Raak, EP, Vles, JS, Dutch Study Group on Child Spasticity. 2008. Intrathecal baclofen therapy in children with intractable spastic cerebral palsy: a cost-effectiveness analysis. Dev Med Child Neurol 50(6):450455.CrossRefGoogle ScholarPubMed
Howard, J, Soo, B, Graham, HK, Boyd, RN, Reid, S, Lanigan, A, Wolfe, R, Reddihough, DS. 2005. Cerebral palsy in Victoria: motor types, topography and gross motor function. J Paediatr Child Health 41(9–10):479483.Google Scholar
Ikeda, H, Kotani, A, Koshikawa, N, Cools, AR. 2010. Differential role of GABAA and GABAB receptors in two distinct output stations of the rat striatum: studies on the substantia nigra pars reticulata and the globus pallidus. Neuroscience 167(1):3139.CrossRefGoogle ScholarPubMed
Krageloh-Mann, I, Horber, V. 2007. The role of magnetic resonance imaging in furthering understanding of the pathogenesis of cerebral palsy. Dev Med Child Neurol 49(12):948.CrossRefGoogle ScholarPubMed
Krageloh-Mann, I, Helber, A, Mader, I, Staudt, M, Wolff, M, Groenendaal, F, DeVries, L. 2002. Bilateral lesions of thalamus and basal ganglia: origin and outcome. Dev Med Child Neurol 44(7):477484.Google Scholar
Macdonell, RA, Talalla, A, Swash, M, Grundy, D. 1989. Intrathecal baclofen and the H-reflex. J Neurol Neurosurg Psychiatry 52(9):11101112.CrossRefGoogle ScholarPubMed
McDonald, AD. 1963. Cerebral palsy in children of very low birth weight. Arch Dis Child 38:579588.CrossRefGoogle ScholarPubMed
Monbaliu, E, Ortibus, E, Roelens, F, Desloovere, K, Deklerck, J, Prinzie, P, de Cock, P, Feys, H. 2010. Rating scales for dystonia in cerebral palsy: reliability and validity. Dev Med Child Neurol 52(6):570575.CrossRefGoogle ScholarPubMed
Monbaliu, E, Ortibus, E, De Cat, J, Dan, B, Heyrman, L, Prinzie, P, De Cock, P, Feys, H. 2012. The dyskinesia impairment scale: a new instrument to measure dystonia and choreoathetosis in dyskinetic cerebral palsy. Dev Med Child Neurol 54(3):278283.CrossRefGoogle Scholar
Motta, F, Stignani, C, Antonello, CE. 2008. Effect of intrathecal baclofen on dystonia in children with cerebral palsy and the use of functional scales. J Pediatr Orthop 28(2):213217.CrossRefGoogle ScholarPubMed
Palisano, RJ, Hanna, SE, Rosenbaum, PL, Russell, DJ, Walter, SD, Wood, EP, Raina, PS, Galuppi, BE. 2000. Validation of a model of gross motor function for children with cerebral palsy. Phys Ther 80(10):974985.CrossRefGoogle Scholar
Pin, TW, McCartney, L, Lewis, J, Waugh, MC. 2011. Use of intrathecal baclofen therapy in ambulant children and adolescents with spasticity and dystonia of cerebral origin: a systematic review. Dev Med Child Neurol 53(10):885895.Google Scholar
Sanger, TD, Delgado, MR, Gaebler-Spira, D, Hallett, M, Mink, JW, Task Force on Childhood Motor Disorders. 2003. Classification and definition of disorders causing hypertonia in childhood. Pediatrics 111(1):e89–97.CrossRefGoogle ScholarPubMed
Saulino, M, Anderson, DJ, Doble, J, Farid, R, Gul, F, Konrad, P, Boster, AL. 2016. Best practices for intrathecal baclofen therapy: troubleshooting. Neuromodulation 19(6):632641.CrossRefGoogle ScholarPubMed
Sellier, E, Platt, MJ, Andersen, GL, Krageloh-Mann, I, De La Cruz, J, Cans, C, Surveillance of Cerebral Palsy Network. 2016. Decreasing prevalence in cerebral palsy: a multi-site European population-based study, 1980 to 2003. Dev Med Child Neurol 58(1):8592.CrossRefGoogle ScholarPubMed
Stokic, DS, Yablon, SA, Hayes, A, Vesovic-Potic, V, Olivier, J. 2006. Dose–response relationship between the H-reflex and continuous intrathecal baclofen administration for management of spasticity. Clin Neurophysiol 117(6):12831289.CrossRefGoogle ScholarPubMed
Ward, A, Hayden, S, Dexter, M, Scheinberg, A. 2009. Continuous intrathecal baclofen for children with spasticity and/or dystonia: goal attainment and complications associated with treatment. J Paediatr Child Health 45(12):720726.CrossRefGoogle ScholarPubMed
Wright, FV, Rosenbaum, PL, Goldsmith, CH, Law, M, Fehlings, DL. 2008. How do changes in body functions and structures, activity, and participation relate in children with cerebral palsy? Dev Med Child Neurol 50(4):283289.CrossRefGoogle ScholarPubMed
Wu, YW, Kuzniewicz, MW, Wickremasinghe, AC, Walsh, EM, Wi, S, McCulloch, CE, Newman, TB. 2015. Risk for cerebral palsy in infants with total serum bilirubin levels at or above the exchange transfusion threshold: a population-based study. JAMA Pediatr 169(3):239246.CrossRefGoogle ScholarPubMed

References

Albanese, A, Bhatia, K, Bressman, SB, Delong, MR, Fahn, S, Fung, VS, Hallett, M, Jankovic, J, Jinnah, HA, Klein, C, Lang, AE, Mink, JW, Teller, JK. 2013. Phenomenology and classification of dystonia: a consensus update. Mov Disord 28(7):863873.CrossRefGoogle ScholarPubMed
Alterman, RL, Tagliati, M. 2007. Deep brain stimulation for torsion dystonia in children. Childs Nerv Syst 23(9):10331040.CrossRefGoogle ScholarPubMed
Castelnau, P, Cif, L, Valente, EM, Vayssiere, N, Hemm, S, Gannau, A, Digiorgio, A, Coubes, P. 2005. Pallidal stimulation improves pantothenate kinase-associated neurodegeneration. Ann Neurol 57(5):738741.CrossRefGoogle ScholarPubMed
Chakraborti, S, Hasegawa, H, Lumsden, DE, Ali, W, Kaminska, M, Lin, JP, Ashkan, K. 2013. Bilateral subthalamic nucleus deep brain stimulation for refractory total body dystonia secondary to metabolic autopallidotomy in a 4-year-old boy with infantile methylmalonic acidemia: case report. J Neurosurg Pediatr 12(4):374379.Google Scholar
Cif, L. 2015. Deep brain stimulation in dystonic cerebral palsy: for whom and for what? Eur J Neurol 22(3):423425.CrossRefGoogle Scholar
Cif, L, Valente, EM, Hemm, S, Coubes, C, Vayssiere, N, Serrat, S, Di Giorgio, A, Coubes, P. 2004. Deep brain stimulation in myoclonus-dystonia syndrome. Mov Disord 19(6):724727.CrossRefGoogle ScholarPubMed
Cif, L, Vasques, X, Gonzalez, V, Ravel, P, Biolsi, B, Collod-Beroud, G, Tuffery-Giraud, S, Elfertit, H, Claustres, M, Coubes, P. 2010. Long-term follow-up of DYT1 dystonia patients treated by deep brain stimulation: an open-label study. Mov Disord 25(3):289299.CrossRefGoogle ScholarPubMed
Cif, L, Gonzalez-Martinez, V, Vasques, X, Corlobe, A, Moura, AM, Bonafe, A, Coubes, P. 2012. Staged implantation of multiple electrodes in the internal globus pallidus in the treatment of primary generalized dystonia. J Neurosurg 116(5):11441152.Google Scholar
Cif, L, Ruge, D, Gonzalez, V, Limousin, P, Vasques, X, Hariz, MI, Rothwell, J, Coubes, P. 2013. The influence of deep brain stimulation intensity and duration on symptoms evolution in an OFF stimulation dystonia study. Brain Stimul 6(4):500505.CrossRefGoogle Scholar
Coubes, P, Echenne, B, Roubertie, A, Vayssiere, N, Tuffery, S, Humbertclaude, V, Cambonie, G, Claustres, M, Frerebeau, P. 1999. Treatment of early-onset generalized dystonia by chronic bilateral stimulation of the internal globus pallidus: apropos of a case. Neurochirurgie 45(2):139144.Google ScholarPubMed
Coubes, P, Roubertie, A, Vayssiere, N, Hemm, S, Echenne, B. 2000. Treatment of DYT1-generalised dystonia by stimulation of the internal globus pallidus. Lancet 355(9222):22202221.CrossRefGoogle ScholarPubMed
Coubes, P, Cif, L, El Fertit, H, Hemm, S, Vayssiere, N, Serrat, S, Picot, MC, Tuffery, S, Claustres, M, Echenne, B, Frerebeau, P. 2004. Electrical stimulation of the globus pallidus internus in patients with primary generalized dystonia: long-term results. J Neurosurg 101(2):189194.CrossRefGoogle ScholarPubMed
DiFrancesco, MF, Halpern, CH, Hurtig, HH, Baltuch, GH, Heuer, GG. 2012. Pediatric indications for deep brain stimulation. Childs Nerv Syst 28(10):17011714.Google Scholar
Fasano, A, Ricciardi, L, Bentivoglio, AR, Canavese, C, Zorzi, G, Petrovic, I, Kresojevic, N, Kostic, VS, Svetel, M, Kovacs, N, Balas, I, Roubertie, A, Mishra, D, Mariotti, P, Temudo, T, Nardocci, N. 2012. Status dystonicus: predictors of outcome and progression patterns of underlying disease. Mov Disord 27(6):783788.CrossRefGoogle ScholarPubMed
Gimeno, H, Tustin, K, Selway, R, Lin, JP. 2012. Beyond the Burke–Fahn–Marsden Dystonia Rating Scale: deep brain stimulation in childhood secondary dystonia. Eur J Paediatr Neurol 16(5):501508.CrossRefGoogle ScholarPubMed
Gonzalez, V, Le Bars, E, Cif, L, van Dokkum, LE, Laffont, I, Bonafe, A, Menjot de Champfleur, N, Zanca, M, Coubes, P. 2015. The reorganization of motor network in hemidystonia from the perspective of deep brain stimulation. Brain Imaging Behav 9(2):223235.CrossRefGoogle ScholarPubMed
Gruber, D, Kuhn, AA, Schoenecker, T, Kivi, A, Trottenberg, T, Hoffmann, KT, Gharabaghi, A, Kopp, UA, Schneider, GH, Klein, C, Asmus, F, Kupsch, A. 2010. Pallidal and thalamic deep brain stimulation in myoclonus-dystonia. Mov Disord 25(11):17331743.CrossRefGoogle ScholarPubMed
Kaminska, M, Lumsden, DE, Ashkan, K, Malik, I, Selway, R, Lin, JP. 2012. Rechargeable deep brain stimulators in the management of paediatric dystonia: well tolerated with a low complication rate. Stereotact Funct Neurosurg 90(4):233239.CrossRefGoogle ScholarPubMed
Keen, JR, Przekop, A, Olaya, JE, Zouros, A, Hsu, FP. 2014. Deep brain stimulation for the treatment of childhood dystonic cerebral palsy. J Neurosurg Pediatr 14(6):585593.Google Scholar
Koy, A, Hellmich, M, Pauls, KA, Marks, W, Lin, JP, Fricke, O, Timmermann, L. 2013. Effects of deep brain stimulation in dyskinetic cerebral palsy: a meta-analysis. Mov Disord 28(5):647654.CrossRefGoogle ScholarPubMed
Kupsch, A, Benecke, R, Muller, J, Trottenberg, T, Schneider, GH, Poewe, W, Eisner, W, Wolters, A, Muller, JU, Deuschl, G, Pinsker, MO, Skogseid, IM, Roeste, GK, Vollmer-Haase, J, Brentrup, A, Krause, M, Tronnier, V, Schnitzler, A, Voges, J, Nikkhah, G,Vesper, J, Naumann, M, Volkmann, J, Deep-Brain Stimulation for Dystonia Study Group. 2006. Pallidal deep-brain stimulation in primary generalized or segmental dystonia. N Engl J Med 355(19):19781990.CrossRefGoogle ScholarPubMed
Kupsch, A, Tagliati, M, Vidailhet, M, Aziz, T, Krack, P, Moro, E, Krauss, JK. 2011. Early postoperative management of DBS in dystonia: programming, response to stimulation, adverse events, medication changes, evaluations, and troubleshooting. Mov Disord 26(Suppl. 1):S37S53.CrossRefGoogle ScholarPubMed
Lumsden, DE, Kaminska, M, Gimeno, H, Tustin, K, Baker, L, Perides, S, Ashkan, K, Selway, R, Lin, JP. 2013a. Proportion of life lived with dystonia inversely correlates with response to pallidal deep brain stimulation in both primary and secondary childhood dystonia. Dev Med Child Neurol 55(6):567574.CrossRefGoogle ScholarPubMed
Lumsden, DE, Lundy, C, Fairhurst, C, Lin, JP. 2013b. Dystonia severity action plan: a simple grading system for medical severity of status dystonicus and life-threatening dystonia. Dev Med Child Neurol 55(7):671672.CrossRefGoogle Scholar
Marks, WA, Honeycutt, J, Acosta, F, Jr, Reed, M, Bailey, L, Pomykal, A, Mercer, M. 2011. Dystonia due to cerebral palsy responds to deep brain stimulation of the globus pallidus internus. Mov Disord 26(9):17481751.Google Scholar
Mink, JW. 2013. Special concerns in defining, studying, and treating dystonia in children. Mov Disord 28(7):921925.CrossRefGoogle ScholarPubMed
Moro, E, Gross, RE, Krauss, JK. 2013. What’s new in surgical treatment for dystonia? Mov Disord 28(7):10131020.Google Scholar
Mure, H, Morigaki, R, Koizumi, H, Okita, S, Kawarai, T, Miyamoto, R, Kaji, R, Nagahiro, S, Goto, S. 2014. Deep brain stimulation of the thalamic ventral lateral anterior nucleus for DYT6 dystonia. Stereotact Funct Neurosurg 92(6):393396.Google Scholar
Ostrem, JL, Racine, CA, Glass, GA, Grace, JK, Volz, MM, Heath, SL, Starr, PA. 2011. Subthalamic nucleus deep brain stimulation in primary cervical dystonia. Neurology 76(10):870878.CrossRefGoogle ScholarPubMed
Ruge, D, Cif, L, Limousin, P, Gonzalez, V, Vasques, X, Hariz, MI, Coubes, P, Rothwell, JC. 2011a. Shaping reversibility? Long-term deep brain stimulation in dystonia – the relationship between effects on electrophysiology and clinical symptoms. Brain 134(Pt 7):21062115.Google Scholar
Ruge, D, Tisch, S, Hariz, MI, Zrinzo, L, Bhatia, KP, Quinn, NP, Jahanshahi, M, Limousin, P, Rothwell, JC. 2011b. Deep brain stimulation effects in dystonia: time course of electrophysiological changes in early treatment. Mov Disord 26(10):19131921.Google Scholar
Ruge, D, Cif, L, Limousin, P, Gonzalez, V, Vasques, X, Coubes, P, Rothwell, JC. 2014. Long term deep brain stimulation withdrawal: clinical stability despite electrophysiological instability. J Neurol Sci 342(1–2):197199.Google Scholar
Schrader, C, Capelle, HH, Kinfe, TM, Blahak, C, Bazner, H, Lutjens, G, Dressler, D, Krauss, JK. 2011. GPi-DBS may induce a hypokinetic gait disorder with freezing of gait in patients with dystonia. Neurology 77(5):483488.CrossRefGoogle ScholarPubMed
Timmermann, L, Pauls, KA, Wieland, K, Jech, R, Kurlemann, G, Sharma, N, Gill, SS, Haenggeli, CA, Hayflick, SJ, Hogarth, P, Leenders, KL, Limousin, P, Malanga, CJ, Moro, E, Ostrem, JL, Revilla, FJ, Santens, P, Schnitzler, A, Tisch, S, Valldeoriola, F, Vesper, J, Volkmann, J, Woitalla, D, Peker, S. 2010. Dystonia in neurodegeneration with brain iron accumulation: outcome of bilateral pallidal stimulation. Brain 133(Pt 3):701712.CrossRefGoogle ScholarPubMed
Vasques, X, Cif, L, Gonzalez, V, Nicholson, C, Coubes, P. 2009. Factors predicting improvement in primary generalized dystonia treated by pallidal deep brain stimulation. Mov Disord 24(6):846853.CrossRefGoogle ScholarPubMed
Vidailhet, M, Yelnik, J, Lagrange, C, Fraix, V, Grabli, D, Thobois, S, Burbaud, P, Welter, ML, Xie-Brustolin, J, Braga, MC, Ardouin, C, Czernecki, V, Klinger, H, Chabardes, S, Seigneuret, E, Mertens, P, Cuny, E, Navarro, S, Cornu, P, Benabid, AL, Le Bas, JF, Dormont, D, Hermier, M, Dujardin, K, Blond, S, Krystkowiak, P, Destee, A, Bardinet, E, Agid, Y, Krack, P, Broussolle, E, Pollak, P, French SPIDY-2 Study Group. 2009. Bilateral pallidal deep brain stimulation for the treatment of patients with dystonia-choreoathetosis cerebral palsy: a prospective pilot study. Lancet Neurol 8(8):709717.Google Scholar
Zorzi, G, Marras, C, Nardocci, N, Franzini, A, Chiapparini, L, Maccagnano, E, Angelini, L, Caldiroli, D, Broggi, G. 2005. Stimulation of the globus pallidus internus for childhood-onset dystonia. Mov Disord 20(9):11941200.CrossRefGoogle ScholarPubMed

References

Ashkan, K, Blomstedt, P, Zrinzo, L, Tisch, S, Yousry, T, Limousin-Dowsey, P, Hariz, MI. 2007. Variability of the subthalamic nucleus: the case for direct MRI guided targeting. Br J Neurosurg 21(2):197200.CrossRefGoogle ScholarPubMed
Bax, M, Tydeman, C, Flodmark, O. 2006. Clinical and MRI correlates of cerebral palsy: the European Cerebral Palsy Study. JAMA 296(13):16021608.CrossRefGoogle ScholarPubMed
Chakraborti, S, Hasegawa, H, Lumsden, DE, Ali, W, Kaminska, M, Lin, JP, Ashkan, K. 2013. Bilateral subthalamic nucleus deep brain stimulation for refractory total body dystonia secondary to metabolic autopallidotomy in a 4-year-old boy with infantile methylmalonic acidemia: case report. J Neurosurg Pediatr 12(4):374379.CrossRefGoogle Scholar
Coubes, P, Roubertie, A, Vayssiere, N, Hemm, S, Echenne, B. 2000. Treatment of DYT1-generalised dystonia by stimulation of the internal globus pallidus. Lancet 355(9222):22202221.Google Scholar
Gainsborough, M, Surman, G, Maestri, G, Colver, A, Cans, C. 2008. Validity and reliability of the guidelines of the surveillance of cerebral palsy in Europe for the classification of cerebral palsy. Dev Med Child Neurol 50(11):828831.CrossRefGoogle ScholarPubMed
Gimeno, H, Tustin, K, Selway, R, Lin, JP. 2012. Beyond the Burke-Fahn-Marsden Dystonia Rating Scale: deep brain stimulation in childhood secondary dystonia. Eur J Paediatr Neurol 16(5):501508.Google Scholar
Gimeno, H, Lumsden, D, Gordon, A, Tustin, K, Ashkan, K, Selway, R, Lin, JP. 2013. Improvement in upper limb function in children with dystonia following deep brain stimulation. Eur J Paediatr Neurol 17(4):353360.CrossRefGoogle ScholarPubMed
Gimeno, H, Tustin, K, Lumsden, D, Ashkan, K, Selway, R, Lin, JP. 2014. Evaluation of functional goal outcomes using the Canadian Occupational Performance Measure (COPM) following deep brain stimulation (DBS) in childhood dystonia. Eur J Paediatr Neurol 18(3):308316.CrossRefGoogle Scholar
Hoon, AH, Jr, Lawrie, WT, Jr, Melhem, ER, Reinhardt, EM, Van Zijl, PC, Solaiyappan, M, Jiang, H, Johnston, MV, Mori, S. 2002. Diffusion tensor imaging of periventricular leukomalacia shows affected sensory cortex white matter pathways. Neurology 59(5):752756.CrossRefGoogle ScholarPubMed
Isaias, IU, Alterman, RL, Tagliati, M. 2009. Deep brain stimulation for primary generalized dystonia: long-term outcomes. Arch Neurol 66(4):465470.Google Scholar
Kaminska, M, Lumsden, DE, Ashkan, K, Malik, I, Selway, R, Lin, JP. 2012. Rechargeable deep brain stimulators in the management of paediatric dystonia: well tolerated with a low complication rate. Stereotact Funct Neurosurg 90(4):233239.CrossRefGoogle ScholarPubMed
Koy, A, Hellmich, M, Pauls, KA, Marks, W, Lin, JP, Fricke, O, Timmermann, L. 2013. Effects of deep brain stimulation in dyskinetic cerebral palsy: a meta-analysis. Mov Disord 28(5):647654.CrossRefGoogle ScholarPubMed
Lin, JP, Lumsden, DE, Gimeno, H, Kaminska, M. 2014. The impact and prognosis for dystonia in childhood including dystonic cerebral palsy: a clinical and demographic tertiary cohort study. J Neurol Neurosurg Psychiatry 85(11):12391244.Google Scholar
Lumsden, DE, Kaminska, M, Gimeno, H, Tustin, K, Baker, L, Perides, S, Ashkan, K, Selway, R, Lin, JP. 2013. Proportion of life lived with dystonia inversely correlates with response to pallidal deep brain stimulation in both primary and secondary childhood dystonia. Dev Med Child Neurol 55(6):567574.Google Scholar
Lumsden, DE, Ashmore, J, Charles-Edwards, G, Selway, R, Lin, JP, Ashkan, K. 2015a. Observation and modeling of deep brain stimulation electrode depth in the pallidal target of the developing brain. World Neurosurg 83(4):438446.CrossRefGoogle ScholarPubMed
Lumsden, DE, Gimeno, H, Tustin, K, Kaminska, M, Lin, JP. 2015b. Interventional studies in childhood dystonia do not address the concerns of children and their carers. Eur J Paediatr Neurol 19(3):327336.Google Scholar
Lumsden, DE, McClelland, V, Ashmore, J, Charles-Edwards, G, Mills, K, Lin, JP. 2015c. Central motor conduction time and diffusion tensor imaging metrics in children with complex motor disorders. Clin Neurophysiol 126(1):140146.CrossRefGoogle ScholarPubMed
McClelland, V, Mills, K, Siddiqui, A, Selway, R, Lin, JP. 2011. Central motor conduction studies and diagnostic magnetic resonance imaging in children with severe primary and secondary dystonia. Dev Med Child Neurol 53(8):757763.CrossRefGoogle ScholarPubMed
Owen, T, Gimeno, H, Selway, R, Lin, JP. 2015. Cognitive function in children with primary dystonia before and after deep brain stimulation. Eur J Paediatr Neurol 19(1):4855.CrossRefGoogle ScholarPubMed
Pinsker, MO, Volkmann, J, Falk, D, Herzog, J, Steigerwald, F, Deuschl, G, Mehdorn, HM. 2009. Deep brain stimulation of the internal globus pallidus in dystonia: target localisation under general anaesthesia. Acta Neurochir (Wien) 151(7):751758.Google Scholar
Sanger, TD, Chen, D, Fehlings, DL, Hallett, M, Lang, AE, Mink, JW, Singer, HS, Alter, K, Ben-Pazi, H, Butler, EE, Chen, R, Collins, A, Dayanidhi, S, Forssberg, H, Fowler, E, Gilbert, DL, Gorman, SL, Gormley, ME, Jr, Jinnah, HA, Kornblau, B, Krosschell, KJ, Lehman, RK, MacKinnon, C, Malanga, CJ, Mesterman, R, Michaels, MB, Pearson, TS, Rose, J, Russman, BS, Sternad, D, Swoboda, KJ, Valero-Cuevas, F. 2010. Definition and classification of hyperkinetic movements in childhood. Mov Disord 25(11):15381549.CrossRefGoogle ScholarPubMed
Silveira-Moriyama, L, Lin, JP. 2015. A field guide to current advances in paediatric movement disorders. Curr Opin Neurol 28(4):437446.CrossRefGoogle ScholarPubMed
Vasques, X, Cif, L, Hess, O, Gavarini, S, Mennessier, G, Coubes, P. 2009. Prognostic value of globus pallidus internus volume in primary dystonia treated by deep brain stimulation. J Neurosurg 110(2):220228.Google Scholar
Vidailhet, M, Yelnik, J, Lagrange, C, Fraix, V, Grabli, D, Thobois, S, Burbaud, P, Welter, ML, Xie-Brustolin, J, Braga, MC, Ardouin, C, Czernecki, V, Klinger, H, Chabardes, S, Seigneuret, E, Mertens, P, Cuny, E, Navarro, S, Cornu, P, Benabid, AL, Le Bas, JF, Dormont, D, Hermier, M, Dujardin, K, Blond, S, Krystkowiak, P, Destee, A, Bardinet, E, Agid, Y, Krack, P, Broussolle, E, Pollak, P, French SPIDY-2 Study Group. 2009. Bilateral pallidal deep brain stimulation for the treatment of patients with dystonia-choreoathetosis cerebral palsy: a prospective pilot study. Lancet Neurol 8(8):709717.CrossRefGoogle ScholarPubMed

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