Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-7479d7b7d-qs9v7 Total loading time: 0 Render date: 2024-07-11T02:42:46.294Z Has data issue: false hasContentIssue false

Chapter 28 - Contraception in Women with Immunosuppressive Diseases

from Section 2A - Sexual and Reproductive Healthcare: Contraception

Published online by Cambridge University Press:  16 January 2024

By
Charles Savona-Ventura ,
Alison Fava  and
Judith-Marie Mifsud
Edited by
Johannes Bitzer  and
Tahir A. Mahmood
Johannes Bitzer
Affiliation:
University Women's Hospital, Basel
Tahir A. Mahmood
Affiliation:
Victoria Hospital, Kirkcaldy
Get access

Summary

An immunosuppressive state can result from either a primary congenital condition reflecting an abnormality of the immune system or a secondary acquired condition resulting from medical conditions – for example, HIV – associated with a depression of the immune system. It can also be the result of incidental or purposeful effects of medications. Purposeful immunosuppressive therapy is commonly used to prevent the rejection of transplanted organs and tissues, but it may also be used to treat autoimmune disorders such as rheumatoid arthritis, systemic lupus erythematosus (SLE), multiple sclerosis, and inflammatory bowel disease (IBD). It may also be used in the treatment of other non-autoimmune inflammatory diseases such as bronchial asthma and ankylosing spondylitis.

Type
Chapter
Information
Textbook of Contraception, Sexual and Reproductive Health , pp. 183 - 186
Publisher: Cambridge University Press
Print publication year: 2024

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Heise, ER. Diseases associated with immunosuppression. Environ Health Perspect. 1982;43:9–19. https://doi.org/10.1289/ehp.82439.CrossRefGoogle ScholarPubMed
Mor, G, Cardenas, I. The immune system in pregnancy: a unique complexity. Am J Reprod Immunol. 2010;63(6):425–33. https://doi.org/10.1111/j.1600-0897.2010.00836.x.CrossRefGoogle ScholarPubMed
Hofmeyr, GJ, Singata, M, Lawrie, TA. Copper containing intra‐uterine devices versus depot progestogens for contraception. Cochrane Database of Systematic Reviews 2010;6:CD007043. https://doi.org/10.1002/14651858.CD007043.pub2.Google Scholar
Shah, NM, Lai, PF, Imami, N, Johnson, MR. Progesterone-related immune modulation of pregnancy and labor. Front. Endocrinol. 2019;10:1–19. https://doi.org/10.3389/fendo.2019.00198.CrossRefGoogle ScholarPubMed
Matubu, A, Hillier, SL, Meyn, LA et al. Depot medroxyprogesterone acetate and norethisterone enanthate differentially impact T‐cell responses and expression of immunosuppressive markers. Am J Reprod Immunol. 2020;83:e13210. https://doi.org/10.1111/aji.13210.CrossRefGoogle ScholarPubMed
World Health Organization. Medical eligibility criteria for contraceptive use. 5th edition. Geneva: World Health Organization, 2015.Google Scholar
Culwell, KR, Curtis, KM. Contraception for women with systemic lupus erythematosus. Journal of Family Planning and Reproductive Health Care 2013;39:9–11. https://doi.org/10.1136/jfprhc-2012-100437.CrossRefGoogle ScholarPubMed
Williams, WV. Hormonal contraception and the development of autoimmunity: A review of the literature. Linacre Q. 2017;84(3):275–95. https://doi.org/10.1080/00243639.2017.1360065.CrossRefGoogle ScholarPubMed
Aggarwal, V, Williams, MD, Beath, SV. Gastrointestinal problems in the immunosuppressed patient. Archives of Disease in Childhood 1998;78:5–8.CrossRefGoogle ScholarPubMed
Tseng, A, Hills-Nieminen, C. Drug interactions between antiretrovirals and hormonal contraceptives. Expert Opin Drug Metab Toxicol. 2013;9(5):559–72.CrossRefGoogle ScholarPubMed
Migali, G, Tintillier, M. Interaction between estradiol and tacrolimus in kidney-transplanted menopausal women. NDT Plus. 2008;1(4):277–8. https://doi.org/10.1093/ndtplus/sfn035.Google ScholarPubMed
Faculty of Sexual and Reproductive Healthcare. Clinical guidance: Drug interactions with hormonal contraception. London: Faculty of Sexual and Reproductive Healthcare, 2017.Google Scholar
Mann, DR, Ansari, AA, Akinbami, MA et al. Neonatal treatment with luteinizing hormone-releasing hormone analogs alters peripheral lymphocyte subsets and cellular and humorally mediated immune responses in juvenile and adult male monkeys. J Clin Endocrinol Metab. 1994;78(2):292–8.Google ScholarPubMed
Khalili, H, Granath, F, Smedby, KE et al. Association between long-term oral contraceptive use and risk of Crohn’s disease complications in a nationwide study. Gastroenterology 2016;150(7):1561–7.e1.CrossRefGoogle Scholar
Gavin, L, Moskosky, S, Carter, M et al. Providing quality family planning services: Recommendations of CDC and the U.S. Office of Population Affairs. Morbidity and mortality weekly report. Recommendations and Reports 2014;63(4):1–54.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×