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Lacosamide

Published online by Cambridge University Press:  01 June 2018

Philip N. Patsalos  and
Erik K. St Louis
Philip N. Patsalos
Affiliation:
UCL Institute for Neurology
Erik K. St Louis
Affiliation:
Mayo Clinic
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The Epilepsy Prescriber's Guide to Antiepileptic Drugs , pp. 120 - 128
Publisher: Cambridge University Press
Print publication year: 2018

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References

Suggested Reading

Baulac, M, Rosenow, F, Toledo, M, Terada, K, Li, T, De Backer, M, Werhahn, KJ, Brock, M. Efficacy, safety, and tolerability of lacosamide monotherapy versus controlled-release carbamazepine in patients with newly diagnosed epilepsy: a phase 3, randomised, double-blind, non-inferiority trial. Lancet Neurology 2017; 16: 43–54.CrossRefGoogle ScholarPubMed
Ben-Menachem, E, Biton, V, Jatuzis, D, Abdul-Khalil, B, Doty, P, Rudd, GD. Efficacy and safety of oral lacosamide as adjunctive therapy in adults with partial-onset seizures. Epilepsia 2007; 48: 1308–1317.CrossRefGoogle ScholarPubMed
Beyreuther, BK, Freitag, J, Heers, C, Krebsfanger, N, Scharfenecker, U, Stohr, T. Lacosamide: a review of preclinical properties. CNS Drug Reviews 2007; 13: 21–42.CrossRefGoogle ScholarPubMed
Biton, V, Rosenfeld, WE, Whitesides, J, Fountain, NB, Vaiciene, N, Rudd, GD. Intravenous lacosamide as replacement of oral lacosamide in patients with partial-onset seizures. Epilepsia 2008; 49: 418–424.Google Scholar
Halasz, P, Kalviainen, R, Mazurkiewicz-Beldzinska, M, Rosenow, F, Doty, P, Hebert, D, Sullivan, T, on behalf of the SP755 Study Group. Adjunctive lacosamide for partial-onset seizures: efficacy and safety results from a randomized controlled study. Epilepsia 2009; 50: 443–453.CrossRefGoogle Scholar
Höfler, J, Trinka, E. Lacosamide as a new treatment option in status epilepticus. Epilepsia 2013; 53: 393–404.CrossRefGoogle Scholar
Kellinghaus, C, Berning, S, Besselmann, M. Intravenous lacosamide as successful treatment for nonconvulsive status epilepticus after failure of first-line therapy. Epilepsy and Behavior 2009; 14: 429–431.CrossRefGoogle ScholarPubMed
Miro, J, Toledo, M, Santamarina, E, Ricciardi, AC, Villanueva, V, Pato, A, Ruiz, J, Juvany, R, Falip, M. Efficacy of intravenous lacosamide as add-on treatment in refractory status epilepticus: a multicentric prospective study. Seizure 2013; 22: 77–79.CrossRefGoogle ScholarPubMed
Novy, J, Pastsalos, PN, Sander, JW, Sisodiya, SM. Lacosamide neurotoxicity associated with concomitant use of sodium channel-blocking antiepileptic drugs: a pharmacodynamic interaction? Epilepsy and Behavior 2011; 20: 20–23.CrossRefGoogle ScholarPubMed
Nunes, VD, Sawer, L, Neilson, J, Sarri, G, Cross, JH. Profile of lacosamide and its long-term treatment of epilepsy: a prospective from the updated NICE guidelines. Neuropsychiatric Disease and Treatment 2013; 9: 467–476.CrossRefGoogle Scholar
Patsalos, PN, Berry, DJ. Pharmacotherapy of the third-generation AEDs: lacosamide, retigabine and eslicarbazepine acetate. Expert Opinion in Pharmacotherapy 2012; 13: 699–715.CrossRefGoogle ScholarPubMed
Verrotti, A, Loiacono, G, Pizzolorusso, A, Parisi, P, Bruni, O, Luchetti, A, Zamponi, N, Cappanera, S, Grosso, S, Kluger, G, Janello, C, Franzoni, E, Elia, M, Spalice, A, Coppola, G, Striano, P, Pavone, P, Savasta, S, Viri, M, Romeo, A, Aloisi, P, Gobbi, G, Ferretti, A, Cusmai, R, Curatolo, P. Lacosamide in paediatric and adult patients: comparison of efficacy and safety. Seizure 2013; 22: 210–216.CrossRefGoogle ScholarPubMed
Vossler, DG, Wechsler, RT, Williams, P, Byrnes, W, Therriault, S; ALEX-MT study group. Long-term exposure and safety of lacosamide monotherapy for the treatment of partial-onset (focal) seizures: results from a multicenter, open-label trial. Epilepsia 2016; 57: 1625–1633.CrossRefGoogle ScholarPubMed
Wechsler, RT, Li, G, French, J, O’Brien, TJ, D’Cruz, O, Williams, P, Goodson, R, Brock, M; ALEX-MT Study Group. Conversion to lacosamide monotherapy in the treatment of focal epilepsy: results from a historical-controlled, multicenter, double-blind study. Epilepsia 2014; 55: 1088–1098.CrossRefGoogle ScholarPubMed

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