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Chapter 13 - Drug-Induced Hemolytic Anemia

from Section 3, Part D - Hemolytic Anemias

Published online by Cambridge University Press:  18 April 2018

Edward J. Benz, Jr.
Affiliation:
Dana Farber Cancer Institute
Nancy Berliner
Affiliation:
Brigham and Women's Hospital, Boston
Fred J. Schiffman
Affiliation:
Children's Hospital, Boston
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Summary

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Type
Chapter
Information
Anemia
Pathophysiology, Diagnosis, and Management
, pp. 95 - 99
Publisher: Cambridge University Press
Print publication year: 2017

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References

Petz, LD GG. Immune Hemolytic Anemias. 2nd ed. Philadelphia: Churchill Livingstone; 2004.Google Scholar
Ahrens, N, Genth, R, Kiesewetter, H, Salama, A. Misdiagnosis in patients with diclofenac-induced hemolysis: new cases and a concise review. Am J Hematol. 2006; 81(2):128131.CrossRefGoogle Scholar
Ahrens, N, Genth, R, Salama, A. Belated diagnosis in three patients with rifampicin-induced immune haemolytic anaemia. Brit J Haematol. 2002; 117(2):441443.CrossRefGoogle ScholarPubMed
Snapper, I, Marks, D, Schwartz, L, Hollander, L. Hemolytic anemia secondary to mesantoin. Ann Intern Med. 1953; 39(3):619623.Google ScholarPubMed
Arndt, PA, Garratty, G. The changing spectrum of drug-induced immune hemolytic anemia. Semin Hematol. 2005; 42(3):137144.CrossRefGoogle ScholarPubMed
Salama, A, Mueller-Eckhardt, C. The role of metabolite-specific antibodies in nomifensine-dependent immune hemolytic anemia. N Engl J Med. 1985; 313(8):469474.Google Scholar
Garratty, G. Immune hemolytic anemia associated with drug therapy. Blood Rev. 2010; 24(4–5):143150.CrossRefGoogle ScholarPubMed
Johnson, ST, Fueger, JT, Gottschall, JL. One center’s experience: the serology and drugs associated with drug-induced immune hemolytic anemia—a new paradigm. Transfusion. 2007; 47(4):697702.Google Scholar
Kirtland, HH, Mohler, DN, Horwitz, DA. Methyldopa inhibition of suppressor-lymphocyte function. N Engl J Med. 1980; 302(15):825832.CrossRefGoogle ScholarPubMed
Pierce, A, Nester, T. Pathology consultation on drug-induced hemolytic anemia. Am J Clin Pathol. 2011; 136(1):712.Google Scholar
Carstairs, KC, Breckenridge, A, Dollery, CT, Worlledge, S. Incidence of a positive direct Coombs test in patients on α-methyldopa. Lancet. 1966; 288(7455):133135.CrossRefGoogle Scholar
Spath, P, Garratty, G, Petz, L. Studies on the immune response to penicillin and cephalothin in humans: ii. immunohematologic reactions to cephalothin administration. J Immunol. 1971; 107(3):860869.Google Scholar
Broadberry, RE, Farren, TW, Bevin, SV, Kohler, JA, Yates, S, Skidmore, I, et al. Tazobactam-induced haemolytic anaemia, possibly caused by non-immunological adsorption of IgG onto patient’s red cells. Transf Med. 2004; 14(1):5357.CrossRefGoogle ScholarPubMed
Arndt, PA, Leger, RM, Garratty, G. Positive direct antiglobulin tests and haemolytic anaemia following therapy with the beta-lactamase inhibitor, tazobactam, may also be associated with non-immunologic adsorption of protein onto red blood cells. Vox Sanguinis. 2003; 85(1):53.Google Scholar
Arndt, P, Garratty, G, Isaak, E, Bolger, M, Lu, Q. Positive direct and indirect antiglobulin tests associated with oxaliplatin can be due to drug antibody and/or drug-induced nonimmunologic protein adsorption. Transfusion. 2009; 49(4):711718.Google Scholar
Arndt, PA, Leger, RM, Garratty, G. Serologic characteristics of ceftriaxone antibodies in 25 patients with drug-induced immune hemolytic anemia. Transfusion. 2012; 52(3):602612.Google Scholar
Kapur, G, Valentini, RP, Mattoo, TK, Warrier, I, Imam, AA. Ceftriaxone induced hemolysis complicated by acute renal failure. Pediatr Blood Cancer. 2008; 50(1):139142.Google Scholar
Garratty, G. Drug-induced immune hemolytic anemia. Hematology Am Soc Hematol Educ Program. 2009:73–79.Google Scholar
Viraraghavan, R, Chakravarty, AG, Soreth, J. Cefotetan-induced haemolytic anaemia. A review of 85 cases. Adverse Drug Reac Toxicol Rev. 2002; 21(1–2):101107.Google Scholar
Croft, JD Jr., Swisher, SN Jr., Gilliland, BC, Bakemeier, RF, Leddy, JP, Weed, RI. Coombs’-test positivity induced by drugs. Mechanisms of immunologic reactions and red cell destruction. Ann Intern Med. 1968; 68(1):176187.Google Scholar

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