As a first attempt to analyze the reactions of Salonican and Sephardic Jews in the United States to the Holocaust, this chapter draws upon Judeo-Spanish newspapers published in New York and Salonica, the prewar and postwar archives of the Jewish community of Salonica - primarily in Judeo-Spanish, as well as French, Greek, and Hebrew - the records of the Sephardic Brotherhood of America, private papers, and memoirs, to demonstrate that the responses, appeals, and fundraising efforts of Sephardic Jews in America formed part of their continued advocacy on behalf of Jews in Salonica over the course of three decades. That sentiment of transnational solidarity persisted despite the devastation of the Holocaust as Salonican Jewish leaders in America sought to help reestablish the Jewish community of Salonica from afar. Their efforts illustrate that the impact of the Holocaust in Greece stretched well beyond the borders of the country. Jewish Salonica became the definitive homeland for all Sephardic Jews once it was wiped off the map. Since then, it has remained a symbol of world Sephardism, despite the demographic and economic decline of the community in its postwar history.