Skip to main content Accessibility help
×
Hostname: page-component-848d4c4894-hfldf Total loading time: 0 Render date: 2024-06-03T07:34:02.864Z Has data issue: false hasContentIssue false

Chapter 7 - Ultrasound Guidance for Botulinum Neurotoxin Therapy

Cervical Dystonia

Published online by Cambridge University Press:  02 November 2023

Daniel Truong
Affiliation:
University of California, Riverside
Dirk Dressler
Affiliation:
Hannover Medical School
Mark Hallett
Affiliation:
National Institutes of Health (NIH)
Christopher Zachary
Affiliation:
University of California, Irvine
Mayank Pathak
Affiliation:
Truong Neuroscience Institute
Get access

Summary

Idiopathic cervical dystonia (CD) is characterized by sustained muscle contraction leading to abnormal postures and twisting movements of the head and neck. BoNT is the gold standard for treatment of the abnormal postures and movements associated with CD. It provides a long duration of symptomatic relief of the pain or postures associated with CD with minimal side effects.

The complex regional anatomy in the craniocervical region increases the potential risks of injections in this area. Ultrasound guidance provides useful information about the depth and thickness of the target muscles, structures to be avoided when inserting/advancing a needle, a safe path to the target and the location of the injectate within the muscle. When treating patients with CD, ultrasound is frequently combined with EMG guidance which provides additional information about muscle activity and potential contribution to a posture. This chapter provides a review of ultrasound guidance for injections for craniocervical dystonia

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2023

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Alter, KE (2010). High-frequency ultrasound guidance for neurotoxin injections. Phys Med Rehabil Clin N Am, 21, 607–30.CrossRefGoogle ScholarPubMed
Alter, KE, Hallett, M, Karp, B (eds.) (2012). Ultrasound-Guided Chemodenervation Procedures: Text and Atlas. New York: Demos Medical, pp. 84107.CrossRefGoogle Scholar
Alter, KE, Karp, BI (2017). Ultrasound guidance for botulinum neurotoxin chemodenervation procedures. Toxins (Basel), 10, 18. https://doi.org/10.3390/toxins10010018CrossRefGoogle ScholarPubMed
Comella, CL, Jankovic, J, Truong, DD, Hanschmann, A, Grafe, S (2011). US. XEOMIN Cervical Dystonia Study Group. Efficacy and safety of incobotulinumtoxinA (NT 201, XEOMINVR, botulinum neurotoxin type A, without accessory proteins) in patients with cervical dystonia. J Neurol Sci, 308, 103–9.CrossRefGoogle Scholar
Costa, J, Espírito-Santo, C, Borges, A et al. (2005). Botulinum toxin type B for cervical dystonia. Cochrane Database Syst Rev, 1, CD004315.Google Scholar
Davidson, J, Jayaraman, S (2011). Guided interventions in musculoskeletal ultrasound: what’s the evidence? Clin Radiol, 66, 140–52.CrossRefGoogle ScholarPubMed
Farrell, M, Karp, BI, Kassavetis, P et al. (2020). Management of anterocapitis and anterocollis: a novel ultrasound guided approach combined with electromyography for botulinum toxin injection of longus colli and longus capitis. Toxins (Basel), 12(10), 626. https://doi.org/10.3390/toxins12100626CrossRefGoogle ScholarPubMed
Glass, GA, Ku, S, Ostrema, JL et al. (2009). Fluoroscopic, EMG-guided injection of botulinum toxin into the longus colli for the treatment of anterocollis. Parkinsonism Relat Disord, 15, 610–13.CrossRefGoogle ScholarPubMed
Hamper, UM, Savader, BL, Sheth, S (1991). Improved needle-tip visualization by color Doppler sonography. AJR Am J Roentgenol, 156, 401–2. https://doi.org/10.2214/ajr.156.2.1898823CrossRefGoogle ScholarPubMed
Henzel, KM, Munin, MC, Kiyonkuru, C et al. (2010). Comparison of surface and ultrasound localization to identify forearm flexor muscles for botulinum toxin therapy. PM R, 2, 642–6.Google Scholar
Hong, JS, Sathe, GG, Niyonkuru, C et al. (2012). Elimination of dysphagia using ultrasound guidance for botulinum toxin injections in cervical dystonia. Muscle Nerve, 46, 535–9.Google Scholar
Lee, IH, Yoon, YC, Sung, DH, Kwon, JW, Jung, JY (2009). Initial experience with imaging-guided intramuscular botulinum toxin injection in patients with idiopathic cervical dystonia. AJR Am J Roentgenol, 192, 9961001.CrossRefGoogle ScholarPubMed
Rodrigues, FB, Duarte, GS, Castelão, M et al. (2021). Botulinum toxin type A versus anticholinergics for cervical dystonia. Cochrane Database Syst Rev, 4, CD004312. https://doi.org/10.1002/14651858.CD004312.pub3Google Scholar
Simpson, DM, Blitzer, A, Brashear, A et al. (2008). Assessment: botulinum neurotoxin for the treatment of movement disorders (an evidence-based review). Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology, 70, 1699–706.Google Scholar
Smith, J, Finnoff, JT (2009a). Diagnostic and interventional musculoskeletal ultrasound: part 1. Fundamentals. PM R, 1, 6475.CrossRefGoogle Scholar
Smith, J, Finnoff, JT (2009b). Diagnostic and interventional musculoskeletal ultrasound: part 2. Clinical applications. PM R, 1, 162–77.Google ScholarPubMed
Truong, D, Brodsky, M, Lew, M et al. (2010). Long-term efficacy and safety of botulinum toxin type A (Dysport) in cervical dystonia. Parkinsonism Relat Disord, 16, 316–23.Google Scholar
Truong, D, Lewitt, P, Cullis, P (1989). Effects of different injection techniques in the treatment of torticollis with botulinum toxin. Neurology, 39(Suppl), 294.Google Scholar
Walter, U, Dudesek, A, Fietzek, UM (2018). A simplified ultrasonography-guided approach for neurotoxin injection into the obliquus capitis inferior muscle in spasmodic torticollis. J Neural Transm (Vienna), 125 , 1037–42. https://doi.org/10.1007/s00702-018-1866-4Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×