Skip to main content Accessibility help
×
Hostname: page-component-7479d7b7d-k7p5g Total loading time: 0 Render date: 2024-07-10T12:40:48.490Z Has data issue: false hasContentIssue false

Case 14: The boy whose bed was always wet: nocturnal enuresis in a child

Published online by Cambridge University Press:  09 February 2024

Jeffrey R. Strawn
Affiliation:
University of Cincinnati, Ohio
Stephen M. Stahl
Affiliation:
University of California, San Diego
Get access

Summary

Which of the following represents a first-line evidence-based pharmacologic intervention for a child with nocturnal enuresis?

Type
Chapter
Information
Case Studies: Stahl's Essential Psychopharmacology
Children and Adolescents
, pp. 223 - 232
Publisher: Cambridge University Press
Print publication year: 2023

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Caldwell, P. H. Y., Sureshkumar, P., Wong, W. C. F. Tricyclic and related drugs for nocturnal enuresis in children. Cochrane Database Syst Rev 2016; 2016(1): CD002117. https://doi.org/10.1002/14651858.CD002117.pub2Google Scholar
Dossche, L., Michelet, R., de Bruyne, P., et al. Desmopressin oral lyophilisate in young children: new insights in pharmacokinetics and pharmacodynamics. Arch Dis Childhood 2021; 106: 597602. https://doi.org/10.1136/archdischild-2019-318225Google Scholar
Findling, R. L., Candler, S. A., Nasser, A. F., et al. Viloxazine in the management of CNS disorders: a historical overview and current status. CNS Drugs 2021; 35(6): 643–53. https://doi.org/10.1007/s40263-021-00825-wGoogle Scholar
Glazener, C. M. A., Evans, J. H. C. Desmopressin for nocturnal enuresis in children. Cochrane Database Syst Rev 2002; 2010(1): CD002112. https://doi.org/10.1002/14651858.CD002112Google Scholar
Johnson, J. K., Liranso, T., Saylor, K., et al. A phase II double-blind, placebo-controlled, efficacy and safety study of SPN-812 (extended-release viloxazine) in children with ADHD. J Atten Disord 2020; 24(2): 348–58. https://doi.org/10.1177/1087054719836159CrossRefGoogle ScholarPubMed
Keten, T., Aslan, Y., Balci, M., et al. Comparison of the efficacy of desmopressin fast-melting formulation and enuretic alarm in the treatment of monosymptomatic nocturnal enuresis. J Pediatr Urol 2020; 16(5): P645.E1–E7. https://doi.org/10.1016/j.jpurol.2020.07.018Google Scholar
Michelet, R., Dossche, L., van Herzeele, C. An integrated paediatric population PK/PD analysis of dDAVP: how do PK differences translate to clinical outcomes? Clin Pharmacokin 2020; 59(1): 81–96. https://doi.org/10.1007/s40262-019-00798-6Google Scholar
Mikkelsen, E. J. Elimination disorders. In Dulcan, M. (ed.), Dulcan’s Textbook of Child and Adolescent Psychiatry, 3rd edn. Washington D.C.: American Psychiatric Publishing, 2021.Google Scholar
Nasser, A., Hull, J. T., Liranso, T., et al. The effect of viloxazine extended-release capsules on functional impairments associated with attention-deficit/hyperactivity disorder (ADHD) in children and adolescents in four phase 3 placebo-controlled trials. Neuropsychiatric Dis Treat 2021; 17: 1751–62. https://doi.org/10.2147/NDT.S312011Google Scholar
Rittig, S., Knudsen, U. B., Norgaard, J. P., Pedersen, E. B., Djurhuus, J. C. Abnormal diurnal rhythm of plasma vasopressin and urinary output in patients with enuresis. Am J Physiol Renal Fluid Electrolyte Physiol 1989; 256(4): F664–71. https://doi.org/10.1152/ajprenal.1989.256.4.f664Google Scholar
Shaffer, D., Costello, A. J., Hill, I. D. Control of enuresis with imipramine. Arch Dis Childhood 1968; 43(232): 665. https://doi.org/10.1136/adc.43.232.665Google Scholar
Yu, C., Garcia-Olivares, J., Candler, S., Schwabe, S., Maletic, V. New insights into the mechanism of action of viloxazine: serotonin and norepinephrine modulating properties. J Exp Pharmacol 2020; 12: 285300. https://doi.org/10.2147/JEP.S256586Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×