In the opening lines of the twenty-third book of his universal history, Diodorus Siculus praises his native Sicily as “the fairest of all islands, since it can contribute greatly to the growth of an empire.”1 Sitting at the intersection of prevailing maritime routes, the island served as a natural landing for ships plying their way between the Mediterranean’s Eastern and Western Basins. Its broad coastal plains supported large urban centers and entrepôts that opened onto the Tyrrhenian Sea to the north, the Ionian Sea to the east, and the vast Libyan Sea to the south and west, inviting contacts from the Italian Peninsula, the Greek mainland, and North Africa. Indeed, located at the heart of the Mediterranean basin, Sicily has occupied an equally central place in the geopolitics of the region across much of the last three millennia.