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33 - Improving the analysis of volumetric capnograms

from 1 - Ventilation

Published online by Cambridge University Press:  05 August 2011

J. S. Gravenstein
Affiliation:
University of Florida
Michael B. Jaffe
Affiliation:
Philip Healthcare
Nikolaus Gravenstein
Affiliation:
University of Florida
David A. Paulus
Affiliation:
University of Florida
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Summary

Carbon dioxide is considered a good marker of ventilation that can best be analyzed by volumetric capnography (VC). VC shows that the interaction of CO2 convection and diffusion at the bronchiolar level creates a limit or stationary interface between these gas transports, the position of which varies among lung units due to airway asymmetry. At the end of inspiration, these small interfaces are located within the bronchioli, but move mouthward during expiration. Fowler's method has potential pitfalls that make the calculation of the airway-alveolar interface insecure, leaving the measurements of VDaw and VTalv prone to errors. The application of the more accurate method as presented in this chapter would facilitate continuous bedside monitoring of lung physiology by means of VC-derived variables and improve their quality. Functional approximation using the Levenberg-Marquardt algorithm (FA-LMA) can be considered a robust, reproducible, and potentially useful tool for analyzing VC-derived clinical data.
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Capnography , pp. 340 - 346
Publisher: Cambridge University Press
Print publication year: 2011

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