To examine the antecedents and consequences of troubled family interaction during the “terrible twos,” 64 of 69 families rearing firstborn sons who were observed in the child's second year of life were observed again in the child's third year. Cluster analysis of parent and child behavior scores was used once more to identify families whose parent-child interactions during parental efforts to control the child looked “troubled” at 27 and/or 33 months so that chronicity of troubled family interaction across the second and third year of life could be appraised. Nine predictor variables suggested by Belsky's model of the determinants of parenting, measured at the end of the first year of life, along with social class, were found to powerfully discriminate families that were troubled never or once from those who were troubled twice from those who were troubled three to four times across the four measurement occasions. Child externalizing problem behavior at 3 years of age was found to be almost monotonically related to chronicity of troubled family interaction, irrespective of whether problem behaviors were reported by mothers, fathers, or daycare providers.

We examined the role of a history of sexual abuse as a predictor of child maltreatment by adolescent mothers in a prospective study of 104 mother-child dyads. Mothers were interviewed about any experienced abuse, and the mother-child dyads were observed in a teaching interaction and in the Strange Situation when the children were 1 year old. Three and a half years later, the mothers were interviewed about their Child Protective Service (CPS) contacts since the birth of their children. The percentage of mothers reporting CPS contacts for their own children was 15.4%, 38.5%, and 83.3%, respectively, for those mothers with no history of sexual abuse, a history of a single incident or brief duration of sexual abuse, and those mothers with a history of chronic sexual abuse (median 24 months duration; test of increasing trend significant at p < .000009). Mothers who reported having been chronically sexually abused as children were significantly more likely to have CPS contacts for their own children, after controlling for history of physical abuse, quality of early teaching interactions, and infant attachment security (both of which also predicted CPS contacts), race, IQ, welfare status at 1 year postpartum, and history of foster care.

The association between attachment and behavior problems was examined for a nonclinical, diverse sociocconomic status (SES) French-Canadian sample of 77 children. Attachment classifications were assigned on the basis of reunion behavior with mother when the children were between 5 and 7 years of age. Teachers rated children's problem behavior using the Socioaffective Profile within 3 months of the attachment assessment (Time 2) and 2 years earlier (Time 1). Results indicated that children with a D classification were more likely than secures or other insecure groups (A or C) to be classified in the problem group at both ages. A majority (80%) of the D group showed problem behavior at some point during the 3–7 year period compared with a minority of A, B, or C children. However, only about 30% of controlling children (like other insecures) had stable problems. Analyses of subclinical scores showed that both controlling and avoidant groups were lower than secures in social competence at Time 1. At Time 2, A group children were lower in externalizing behavior, and C group children were higher. These results extend the association between the D classification and maladaptation previously found for clinical and high-risk samples to a nonclinical, mixed SES sample.

Two cohorts of adolescents who were categorized at either 21 or 31 months of age as extremely inhibited or uninhibited completed the Youth Self-Report (YSR), and their parents completed the Child Behavior Checklist (CBCL). In the second year, inhibited children typically cease ongoing behavior and vocalizing, seek comfort from a familiar person, or withdraw in response to unfamiliar situations. By contrast uninhibited children do not become subdued by novelty and are sociable and outgoing, often vocalizing, smiling, and approaching unfamiliar persons or objects. The 13-year-old adolescents who had been categorized as inhibited at 21 months of age scored significantly lower than adolescents originally classified as uninhibited on the Total Externalizing, Delinquent Behavior, and Aggressive Behavior Scales. Parental ratings of Total Externalizing and Aggressive behavior on the CBCL agreed with the Youth Self-Report. The second cohort of adolescents who had been selected at 31 months yielded similar findings, but only for males. These results suggest that important aspects of the original temperamental profile have been preserved over a 12-year period.

This series of four studies examined the psychosocial functioning of children, adolescents, and adults with developmental dyslexia. One sample of nonreferred dyslexic and nondyslexic men, and three different samples of dyslexic and normally achieving control children and adolescents were studied. The child samples included both clinic-referred and nonreferred populations, and sibling and nonsibling control designs. Variables assessed included depressive and ADHD symptomatology, self-concept and, in the adult sample, socioeconomic status and other life adjustment variables.

We found that, across three samples, children and adolescents report lower global self-worth and lower perceived competence in scholastic domains, more depressive symptomatology, and (both by self- and parent report) more ADHD symptomatology than normal achievers. In contrast, adult dyslexic men, while also perceiving themselves as less intelligent than their peers, reporting more generalized psychological distress, and showing less social mobility, were nonetheless comparable to their peers in terms of global self-worth, depressive symptomatology, and other indices of adult adjustment and satisfaction. Results are discussed in terms of a developmental “niche-finding” model, in which the shift into adult life may foster more constructive experiences and internal processes.

The most commonly reported finding from structural brain studies in autism is abnormality of the cerebellum. Autopsy and magnetic resonance imaging (MR) studies from nine independent research groups have found developmental abnormality of the cerebellar vermis or hemispheres in the majority of the more than 240 subjects with autism who were studied. We reported previously that patients with autism and those with acquired damage to the cerebellum were slow to shift attention between and within sensory modalities. In this study, we found that patients with autism who come from a group with significant cerebellar abnormality were also slow to orient attention in space.

A subgroup of these patients who have additional or corollary parietal abnormality, like previously studied patients with acquired parietal damage, were also slow to detect and respond to information outside an attended location. Posner, Walker, Friedrich, and Rafal (1984) showed that patients with parietal lesions were slow to respond to contralesional information if they were attending an ipsilesional location. This study has replicated that finding in patients with autism who have developmental bilateral parietal abnormality, and found a strong correlation between the attentional deficits and the amount of neuroanatomic parietal abnormality in these patients. This is the first time in the study of autism that there is evidence for a statistically significant association of the size of a specific brain structural abnormality with a specific behavioral deficit.

These findings illustrate that in autism different patterns of underlying brain pathology may result in different patterns of functional deficits. In conjunction with previous studies of patients with acquired lesions, these data have implications for the brain bases of normal attention. The cerebellum may affect the speed with which attentional resources can be activated, while the parietal cortex affects the ability to use those resources for efficient information processing at locations outside an attended focus. Deficits in the speed and efficiency with which neural activity can be modulated to facilitate processing can clearly influence cognitive function. Such deficits may contribute to the behavioral disabilities that characterize autism.

In a sample of 112 psychiatric inpatients with mild mental retardation, lower premorbid social competence was significantly related to symptom expression in action compared to thought. Both of these variables were correlated with length of current hospitalization. Premorbid social competence and thought-action orientation have been major variables in developmental research on psychopathology in patients without mental retardation. These results indicate that these variables can be applied to differentiate developmental level among inpatients with mild mental retardation and that these developmental distinctions are related to other clinical variables, as has been found for inpatients without mental retardation. The findings also attest to the heterogeneity in developmental level among inpatients with mild mental retardation.