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Effects of long-term plant sterol or stanol ester consumption on lipid and lipoprotein metabolism in subjects on statin treatment – CORRIGENDUM

Published online by Cambridge University Press:  02 July 2009

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Abstract

Type
Corrigenda
Copyright
Copyright © The Authors 2009

In error, an incorrect version of Table 3 was published. The correct version can be found below.

Table S3 Effects of plant sterol and stanol ester consumption on serum concentrations of plant sterols, plant stanols, lathosterol and oxysterols

(Mean values and their standard deviations)

Values are expressed as 1102 × μmol/mmol cholesterol or 2μg/mmol serum.

a Significantly different from the control group (P < 0·05).

b Significantly different from the control group (P < 0·001).

Results

Plant sterols and stanols, cholesterol precursors, oxysterols and 7a-hydroxy-4-cholesten-3-one

For: Both cholesterol-standardised sitostanol and campestanol concentrations were significantly increased in the stanol ester group as compared with the control group. Surprisingly, serum cholesterol-standardised campestanol concentrations further increased after 45 weeks in the plant stanol group.

Read: Both cholesterol-standardised sitostanol and campestanol concentrations were significantly increased in the stanol ester group as compared with the control group.

Discussion

For: Although the initial increase in serum cholesterol-standardised campestanol concentrations is in line with earlier observations, serum cholesterol-standardised campestanol concentrations further increased after 45 weeks. This effect was not only observed in the plant stanol group, but also in the control and the plant sterol groups, although to a lesser extent. Since all samples of one subject were analysed in the same analytical run and samples from the three groups were randomly distributed over the runs, these increases cannot be attributed to technical problems and warrant further investigation.

Read: The increase in serum cholesterol-standardised campestanol concentrations is in line with earlier observations (refs)

Figure 0

Table S3 Effects of plant sterol and stanol ester consumption on serum concentrations of plant sterols, plant stanols, lathosterol and oxysterols(Mean values and their standard deviations)