Ten depressed patients were assessed on an auditory signal detection task; testing was repeated on remission. The patients' clinical state was monitored by means of the Hamilton rating scale and the Beck Depression Inventory. The task was performed under three conditions: 2 button (Yes/No); 1 button (Yes); 1 button (No). The findings indicated lower motor responsiveness during depression, consistent with Seligman's learned helplessness model. The measure of auditory sensitivity was also lowered during depression, possibly attributable to attentional disturbance. It is suggested that the lowered initiation of voluntary responses may be an important factor in the assessment of cognitive functioning during depression; such deficits may be reduced if the task does not permit the omission of a response.

Sixteen manic patients were rated fortnightly on the Present State Examination and a new manic rating scale. After 4 weeks of treatment a high proportion of symptoms had decreased significantly, but some symptoms likely to affect social functioning persisted. The group displayed many depressive and anxiety symptoms in addition to recognized manic symptoms.