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Symposium on ‘Nutrition and the elderly’ Protein-energy malnutrition in older subjects

Published online by Cambridge University Press:  18 April 2008

John E. Morley*
Affiliation:
Geriatric Research, Education and Clinical Center, St Louis VAMC, St Louis, MO 63125, USA and Division of Geriatric Medicine, St Louis University Medical School, St Louis, MO 63104, USA
*
Corresponding author: Dr J. E. Morley, fax + I 314 771 8575, email MORLEYJE@SLU.EDU
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Abstract

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Type
Symposium on ‘Nutrition and the elderly’
Copyright
Copyright © The Nutrition Society 1998

References

Aisner, J, Parnes, H, Tait, N, Hickman, M, Forrest, A, Greco, FA & Tchekmedyian, NS (1990) Appetite stimulation and weight gain with megestrol acetate. Seminars in Oncology 17, Suppl. 9, 27.Google ScholarPubMed
Anonymous (1994) Daily dietary fat and total food energy intakes. Third National Health and Nutrition Examination Survey, phase III. 1988–1991. Morbidity and Mortality Weekly Report 43, 116125.Google Scholar
Anonymous (1991) Perioperative total parenteral nutrition in surgical patients. The Veterans Affairs Total Parenteral Nutrition Cooperative Study Group. New England Journal of Medicine 325, 525532.CrossRefGoogle Scholar
Bastow, MD, Rawlings, J & Allison, SP (1983) Benefits of supplementary tube feeding after fractured neck of femur. British Medical Journal 287, 15891592.CrossRefGoogle ScholarPubMed
Bertelemy, P, Bouisson, M, Vellas, B, Moreau, J, Nicole-Vaysse, A, Albarede, JL & Ribet, A (1992) Postprandial cholecystokinin secretion in elderly with protein-energy under-nutrition. Journal of the American Geriatrics Society 40, 365369.CrossRefGoogle Scholar
Blazer, D, Bachas, JR & Hughes, DC (1987) Major depression with melancholia: a comparison of middle-aged and elderly adults. Journal of the American Geriatrics Society 35, 927932.CrossRefGoogle ScholarPubMed
Brocker, P, Vellas, B, Albarede, J & Poynard, T (1994) A two-center, randomized double-blind trial of ornithine oxoglutarate in 194 elderly, ambulatory, convalescent subjects. Age and Ageing 23, 303306.CrossRefGoogle Scholar
Buckler, DA, Kelber, ST & Goodwin, JS (1994) The use of dietary restrictions in malnourished nursing home patients. Journal of the American Geriatrics Society 42, 11001102.CrossRefGoogle ScholarPubMed
Bush, LA, Horenkamp, N, Morley, JE & Spiro, A (1996) D-E-N-T-A-L: a rapid self-administered screening instrument to promote referrals for further evaluation in older adults. Journal the American Geriatrics Society 44, 979981.CrossRefGoogle ScholarPubMed
Castle, S, Nguyen, C, Joaquin, A, Coyne, B, Heuston, C, Chan, A, Percy, L & Ohmen, J (1995) Megestrol acetate suspension therapy in the treatment of geriatric anorexidcachexia in nursing home patients. Journal of the American Geriatrics Society 43, 835836.CrossRefGoogle ScholarPubMed
Clarkston, WK, Pantano, MM, Morley, E, Horowitz, M, Littlefield, JM & Burton, FR (1997) Evidence for the anorexia of aging: gastrointestinal transit and hunger in healthy elderly vs. young adults. American Journal of Physiology 272, R243R248.Google ScholarPubMed
Cook, CG, Andrews, JM, Jones, KL, Wittert, GA, Chapman, IM, Morley, JE & Horowitz, M (1997) Effects of small intestinal nutrient infusion on appetite and pyloric motility are modified by age. American Journal of Physiology 273, R755R761.Google ScholarPubMed
Coulston, AM, Mandelbaum, D & Reaven, GM (1990) Dietary management of nursing home residents with non-insulin-dependent diabetes mellitus. American Journal of Clinical Nutrition 51, 6771.CrossRefGoogle ScholarPubMed
Deitch, EA (1988) Does the gut protect or injure patients in the ICU? Prospectives in Critical Care 1, 131.Google Scholar
Delmi, M, Rapin, CH, Bengoa, JM, Delmas, PD, Vasey, H & Bonjour, JP (1990) Dietary supplementation in elderly patients with fractured neck of the femur. Lancet 335, 10131016.CrossRefGoogle ScholarPubMed
Edwards, BJ, Perry, HM, Kaiser, FE, Morley, JE, Kraenzle, D, Stevenson, R & Kreutter, D (1996) Relationship of age and calcitonin generelated peptide to postprandial hypotension. Mechanisms of Ageing Development 87, 6173.CrossRefGoogle ScholarPubMed
Fitten, LJ, Morley, JE, Gross, PL, Petry, SD & Cole, KD (1996) Depression. Journal of the American Geriatrics Society 37, 459472.CrossRefGoogle Scholar
Fonesca, V & Wall, J (1995) Diet and diabetes in the elderly. Clinics in Geriatric Medicine 11, 613624.CrossRefGoogle Scholar
Gosnell, BA, Levine, AS & Morley, JE (1983) The effects of aging on opioid modulation of feeding in rats. Life Sciences 32, 27932799.CrossRefGoogle ScholarPubMed
Guigoz, Y, Vellas, RJ & Gamy, PJ (1994) Mini Nutritional Assessment: a practical assessment tool for grading the nutritional status of elderly patients. Facts and Research in Gerontology 4, Suppl. 2, 1559.Google Scholar
Johnson, LE, Dooley, PA & Gleick, JB (1993) Oral nutritional supplement use in elderly nursing home patients. Journal of the American Geriatrics Society 41, 974–952.CrossRefGoogle ScholarPubMed
Jones, KL, Doran, SM, Hveem, K, Bartholomeusz, FD, Morley, JE, Sun, WM, Chatterton, BE & Horowitz, M (1997) Relation between postprandial satiation and antral area in normal subjects. American Journal of Clinical Nutrition 66, 127132.CrossRefGoogle ScholarPubMed
Kaiser, FE & Morley, JE (1994) Idiopathic CD4+ T lymphopenia in older persons. Journal of the American Geriatrics Society 42, 12911294.CrossRefGoogle ScholarPubMed
Kaiser, FE, Silver, AJ & Morley, JE (1991) The effect of recombinant human growth hormone on malnourished older individuals. Journal of the American Geriatrics Society 39, 235240.CrossRefGoogle ScholarPubMed
Katz, IR, Beaston-Wimmer, P, Parmelee, P, Friedman, E & Lawton, MP (1994) Failure to thrive in the elderly: exploration of the concept and delineation of psychiatric components. Journal Geriatric Psychiatry and Neurology 6, 161169.CrossRefGoogle Scholar
Kavaliers, M & Hirst, M (1985) The influence of opiate agonists on day-night feeding rhythms in young and old mice. Brain Research 326, 160167.CrossRefGoogle ScholarPubMed
Krahn, DD, Gosnell, BA, Levine, AS & Morley, JE (1988) Behavioral effects of corticotropin-releasing factor: localization and characterization of central effects. Brain Research 443, 6349.CrossRefGoogle ScholarPubMed
Larsson, F, Unosson, M, Ek, AC & Bjurulf, P (1990) Effect of dietary supplement on nutritional status and clinical outcome in 501 geriatric patients – a randomized study. Clinical Nutrition 9, 179184.CrossRefGoogle Scholar
Linn, BS & Jensen, J (1984) Malnutrition and immunocompetence in older and younger outpatients. Southern Medical Journal 77, 10981102.CrossRefGoogle ScholarPubMed
Mainguet, P (1972) Effect of cyproheptadineon anorexia and loss of weight in adults. Practitioner 208, 797800.Google ScholarPubMed
Margolick, JB & Donnenberg, (1997) T cell homeostasis in HIV+ infection. Seminars in Hematology 9, 381388.Google Scholar
Melanson, KJ, Saltzman, E, Russell, RR & Roberts, SB (1997) Fat oxidation in response to four graded challenges in younger and older women. American Journal of Clinical Nutrition 66, 860866.CrossRefGoogle ScholarPubMed
Miller, DK, Carter, ME, Sigmund, RH, Smith, JQ, Miller, JP, Bentley, JA, McDonald, K, Coe, RM & Morley, JE (1996) Nutritional risk in inner-city-dwelling older black Americans. Journal of the American Geriatrics Society 44, 959962.CrossRefGoogle ScholarPubMed
Miller, DK, Morley, JE & Rubenstein, LZ (1990) Formal geriatric assessment instruments and the care of elderly general assessment instruments. Journal of the American Geriatrics Society 38, 645651.CrossRefGoogle ScholarPubMed
Miller, DK, Morley, JE, Rubenstein, LZ & Pietreszka, FM (1991) Abnormal eating attitudes and body image in older undernourished individuals. Journal of the American Geriatrics Society 39, 462468.CrossRefGoogle ScholarPubMed
Morley, JE (1989) Death by starvation: a modem American problem. Journal of the American Geriatrics Society 37, 184185.CrossRefGoogle Scholar
Morley, JE (1997) Anorexia of aging: physiologic and pathologic. American Journal of Clinical Nutrition 66, 760773.CrossRefGoogle ScholarPubMed
Morley, JE, Farr, S & Flood, J (1996) Peripherally administered calcitonin gene related peptide decreases food intake in mice. Peptides 17, 511516.CrossRefGoogle ScholarPubMed
Morley, JE & Flood, JF (1992) Competitive antagonism of nitric oxide synthetase causes weight loss in mice. Life Sciences 51, 12851289.CrossRefGoogle ScholarPubMed
Morley, JE, Flood, JF & Silver, AJ (1990) Opioid peptides and aging. Annals of the New York Academy of Sciences 579, 123132.CrossRefGoogle ScholarPubMed
Morley, JE, Kaiser, FE, Perry, HM, Patrick, P, Morley, PM, Stauber, PM, Vellas, B, Baumgartner, RN & Garry, PJ (1997) Longitudinal changes in testosterone, luteinizing hormone and follicle stimulating hormone in healthy older males. Metabolism 46, 410413.CrossRefGoogle Scholar
Morley, JE & Kraenzle, D (1994) Causes of weight loss in a community nursing home. Journal of the American Geriatrics Society 42, 583585.CrossRefGoogle Scholar
Morley, JE & Kraenzle, D (1995) Weight loss. Journal of the American Geriatrics Society 43, 8283.Google Scholar
Morley, JE, Kraenzle, D, Jensen, JM, Gettman, J & Tetter, L (1994) The role of a nurse practitioner in quality improvement in nursing homes. Nursing Home Medicine 2, 1117.Google Scholar
Morley, JE & Silver, AJ (1995) Nutritional issues in nursing home care. Annals of Internal Medicine 123, 850859.CrossRefGoogle ScholarPubMed
Morley, JE, Silver, AJ, Miller, DK & Rubenstein, LZ (1989) The anorexia of the elderly. Annals of the New York Academy of Sciences 575, 5059.CrossRefGoogle ScholarPubMed
Murphy, MG, Plunkett, LM, Gertz, BJ, He, W, Wittreich, J, Polvino, WM & Clemmons, DR (1998) MK-667, an orally active growth hormone secretagogue, reverses diet-induced catabolism. Journal of Clinical Endocrinology and Metabolism 83, 320325.Google ScholarPubMed
Nelson, K, Walsh, D, Deeter, P & Sheeham, F (1994) A phase II study of delta-9-tetrahydrocannabinol for appetite stimulation in cancer-associated anorexia. Journal of Palliative Care 10, 1418.Google ScholarPubMed
Nemeroff, CB, Bissetti, G & Widerov, E (1984) Elevated concentra- tions of corticotropin-releasing-factor-like immunoreactivity in depressed patients. Science 226, 13421343.CrossRefGoogle Scholar
Niskanen, L, Piirainen, M, Koljonen, M & Uusitupa, M (1993) Resting energy expenditure in relation to energy intake in patients with Alzheimer's disease, multi-infarct dementia and in control women. Age and Ageing 22, 132137.CrossRefGoogle ScholarPubMed
Ostlund, RE Jr, Yang, JW, Klein, S & Gingerich, R (1996) Relation between plasma leptin concentration and body fat, gender, diet, age, and metabolic covariates. Journal of Clinical Endocrinology and Metabolism 81, 39093913.Google ScholarPubMed
Perry, HM III, Morley, JE, Horowitz, M, Kaiser, FE, Miller, DK & Wittert, G (1997) Body composition and age in African American and Caucasian women; relationship to plasma leptin levels and gonadal steroids. Metabolism 46, 13881406.CrossRefGoogle Scholar
Poehlman, ET (1993) Regulation of energy expenditure in aging humans. Journal of the American Geriatrics Society 41, 552559.CrossRefGoogle ScholarPubMed
Portnoi, VA (1997) Helicobacter pylori infection and anorexia of aging. Archives of Internal Medicine 157, 269272.CrossRefGoogle ScholarPubMed
Posner, BM, Jette, AM, Smith, KW & Miller, DR (1993) Nutrition and health risks in the elderly: the Nutrition Screening Initiative. American Journal of Public Health 83, 972978.CrossRefGoogle ScholarPubMed
Roberts, SB, Fuss, P, Heymann, MB, Evans, WJ, Tsay, R, Rasmussen, H, Fiatorone, M, Cortiella, J, Dallal, GE & Young, VR (1994) Control of food intake in older men. Journal of the American Medical Association 272, 16011606.CrossRefGoogle ScholarPubMed
Rolls, BJ, Dimeo, KA & Shide, DJ (1995) Age-related impairments in the regulation of food intake. American Journal of Clinical Nutrition 62, 923931.CrossRefGoogle ScholarPubMed
Roubenoff, R, Roubenoff, RA & Cannon, JG (1994) Rheumatoid cachexia: cytokine driven hypermetabolism and loss of lean body mass in chronic inflammation. Journal of Clinical Investigation 93, 23792386.CrossRefGoogle Scholar
Rubin, CH, Posner, BM, Peterson, DE & CARE International Working Group (1994) Nutritional Survey of an elderly Russian population. American Journal of Preventative Medicine 10, 7176.CrossRefGoogle ScholarPubMed
Sandman, PO, Adolfsson, R, Nygren, C, Halimans, G & Umbiac, B (1987) Nutritional status and dietary intake in institutionalized patients with Alzheimer's disease and multi-infarct dementia. Journal of the American Geriatrics Society 35, 3138.CrossRefGoogle Scholar
Schiffman, SS (1993) Perception of taste and smell in elderly persons. Critical Review of Food, Science, and Nutrition 33, 1726.CrossRefGoogle ScholarPubMed
Sih, R (1996) Cholesterol and the healthy senior. Annual Review of Gerontology and Geriatrics 15, 229254.Google Scholar
Sih, R, Morley, JE, Kaiser, FE & Perry, HM (1997) Testosterone replacement in older hypogonadal men: a 12 month randomized controlled trial. Journal of Clinical Endocrinology and Metabolism 82, 16611667.CrossRefGoogle Scholar
Silver, AJ, Flood, JF, Song, AM & Morley, JE (1989) Evidence for a physiological role for CCK in the regulation of food intake in mice. American Journal of Physiology 256, R646R652.Google ScholarPubMed
Silver, AJ, Guillen, CP. Kahl, MJ & Morley, JE (1993) Effect of aging on body fat. Journal of the American Geriatrics Society 41, 211213.CrossRefGoogle ScholarPubMed
Silver, AJ, Morley, JE, Strome, LS, Jones, D & Vickers, L (1988) Nutritional status in an academic nursing home. Journal of the American Geriatrics Society 36, 487491.CrossRefGoogle Scholar
Steen, B, Isaksson, B & Svanborg, A (1979) Body composition at 70 and 75 years of age: a longitudinal population study. Journal of Clinical and Experimental Gerontology 11, 185192.Google Scholar
Sullivan, DH, Martin, W, Flaxman, N & Hagen, JE (1993) Oral health problems and involuntary weight loss in a population of frail elderly. Journal of the American Geriatrics Society 41, 725731.CrossRefGoogle Scholar
Thompson, MP & Moms, LK (1991) Unexplained weight loss in the ambulatory elderly. Journal of the American Geriatrics Society 39, 497500.CrossRefGoogle ScholarPubMed
Tucker, H & Miguel, S (1996) Cost containment through nutrition intervention. Nutrition Reviews 54, 111121.CrossRefGoogle ScholarPubMed
Wallace, JI, Schwartz, RS, LaCroix, AZ, Uhlmann, RF & Pearlman, RA (1995) Involuntary weight loss in older outpatients: incidence and clinical significance. Journal of the American Geriatrics Society 43, 329337.CrossRefGoogle ScholarPubMed
Westin, T, Jansson, A, Zenckert, C, Hallstrom, T & Edstrum, S (1988) Mental depression is associated with malnutrition in patients with head and neck cancer. Archives of Otolaryngology Head and Neck Surgery 114, 14491453.CrossRefGoogle ScholarPubMed
White, JV, Ham, RJ, Lipschitz, DA, Dwyer, JT & Wellman, NS (1991) Consensus of the Nutrition Screening Initiative: risk factors and indicators of poor nutritional status in older Americans. Journal of the American Dietetic Association 91, 783787.CrossRefGoogle ScholarPubMed
Wilson, M-MG, Purushothaman, R & Morley, JE (1997) Oral preloads and aging. Journal of the American Geriatrics Society 37, 108A.Google Scholar
Wilson, M-MG, Vaswani, S, Lui, D, Morley, JE & Miller, DK (1998) Prevalence and causes of undemutrition in outpatients. American Journal of Medicine 104, 5663.CrossRefGoogle Scholar