Skip to main content Accessibility help
×
Home
Hostname: page-component-888d5979f-22jsc Total loading time: 0.222 Render date: 2021-10-26T15:13:33.725Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "metricsAbstractViews": false, "figures": true, "newCiteModal": false, "newCitedByModal": true, "newEcommerce": true, "newUsageEvents": true }

Molecular mechanisms involved in the nutritional and hormonal regulation of growth in pigs

Published online by Cambridge University Press:  28 February 2007

John M. Brameld
Affiliation:
Department of Applied Biochemistry and Food Science, University of Nottingham, Sutton Bonington Campus, Loughborough LE12 5RD
Rights & Permissions[Opens in a new window]

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Symposium on ‘Regulation of nitrogen retention in farm animals’
Copyright
Copyright © The Nutrition Society 1997

References

Ambler, G. R., Breier, B. H., Surus, A., Blair, H. T., McCutcheon, S. N., Silbergeld, A. & Gluckman, P. D. (1992). The interrelationship between and the regulation of hepatic growth hormone receptors and circulating GH binding protein in the pig. Acta Endocrinologica 126, 155161.Google ScholarPubMed
Arany, E., Strain, A. J., Hube, M. J., Phillips, I. D. & Hill, D. J. (1993). Interactive effects of nutrients and hormones on the expression of insulin-like growth factor binding protein-1 (IGFBP-1) mRNA and peptide, and IGF-I release from isolated adult rat hepatocytes. Journal of Cellular Physiology 155, 426435.CrossRefGoogle ScholarPubMed
Barreca, A., Voci, A., Minuto, F., de Marchis, M., Cecchelli, E., Fugassa, E., Giordano, G. & Gallo, G. (1992). Effect of epidermal growth factor on insulin-like growth factor-I (IGF-I) and IGF-binding protein synthesis by adult rat hepatocytes. Molecular and Cellular Endocrinology 84, 119126.CrossRefGoogle ScholarPubMed
Baumbach, W. R., Horne, D. L. & Logan, J. S. (1989). The growth hormone-binding protein in the rat serum is an alternatively spliced form of the rat growth hormone receptor. Genes & Development 3, 11991205.CrossRefGoogle ScholarPubMed
Boni-Schnetzler, M., Schmid, C., Meier, P. J. & Froesch, E. R. (1991). Insulin regulates insulin-like growth factor I mRNA in rat hepatocytes. American Journal of Physiology 260, E846E851.Google ScholarPubMed
Brameld, J. M., Atkinson, J. L., Budd, T. J., Saunders, J. C., Pell, J. M., Salter, A. M., Gilmour, R. S. & Buttery, P. J. (1996 a). Expression of insulin-like growth factor-I (IGF-I) and growth hormone receptor (GHR) mRNA in liver, skeletal muscle and adipose tissue of different breeds of pig. Animal Science 62, 555559.CrossRefGoogle Scholar
Brameld, J. M., Atkinson, J. L., Saunders, J. C., Pell, J. M., Buttery, P. J. & Gilmour, R. S. (1996 b). Effects of growth hormone administration and dietary protein intake on insulin-like growth factor-I (IGF-I) and growth hormone receptor (GHR) mRNA expression in porcine liver, skeletal muscle and adipose tissue. Journal of Animal Science 74, 18321841.CrossRefGoogle ScholarPubMed
Brameld, J. M., Weller, P. A., Pell, J. M., Buttery, P. J. & Gilmour, R. S. (1995 a). Ontogenic study of irisulin-like growth factor-I and growth hormone receptor mRNA expression in porcine liver and skeletal muscle. Animal Science 61, 333339.CrossRefGoogle Scholar
Brameld, J. M., Weller, P. A., Saunders, J. C., Buttery, P. J. & Gilmour, R. S. (1995 b). Hormonal control of insulin-like growth factor-I (IGF-I) and growth hormone receptor (GHR) mRNA expression by porcine hepatocytes in culture. Journal of Endocrinology 146, 239245.CrossRefGoogle ScholarPubMed
Breier, B. H. & Sauerwein, H. (1995). Regulation of growth in ruminants by the somatotropic axis. In Ruminant physiology: digestion, metabolism, growth and reproduction. proceedings of the eighth international symposium on ruminant physiology, pp. 451474 [Engelhardt, W. V., Leonhard-Marek, S., Breves, G. and Giesecke, D., editors]. Stuttgart, Germany: Ferdinand enke verlag.Google Scholar
Buonomo, F. C. & Baile, C. A. (1991). Influence of nutritional deprivation on insulin-like growth factor I, somatotropin, and metabolic hormones in swine. Journal of Animal Science 69, 755760.CrossRefGoogle ScholarPubMed
Campbell, R. G., Johnson, R. J., King, R. H., Taverner, M. R. & Meisinger, D. J. (1990). Interaction of dietary protein content and exogenous porcine growth hormone administration on protein and lipid accretion rates in growing pigs. Journal of Animal Science 68, 32173225.CrossRefGoogle ScholarPubMed
Caperna, T. J., Steele, N. C., Komarek, D. R., McMurtry, J. P., Rosebrough, R. W., Solomon, M. B. & Mitchell, A. D. (1990). Influence of dietary protein and recombinant porcine somatotropin administration in young pigs: Growth, body composition and hormone status. Journal of Animal Science 68, 42434252.CrossRefGoogle ScholarPubMed
Chung, C. S. & Etherton, T. D. (1986). Characterization of porcine growth hormone (pGH) binding to porcine liver microsomes: Chronic administration of pGH induces pGH binding. Endocrinology 119, 780786.CrossRefGoogle ScholarPubMed
Cioffi, J. A., Wang, X. & Kopchick, J. J. (1990). Porcine growth hormone receptor cDNA sequence. Nucleic Acid Research 18, 6451.CrossRefGoogle ScholarPubMed
Coleman, M. E. & Etherton, T. D. (1991). Effects of exogenous growth hormone on serum insulin-like growth factor-binding proteins in growing pigs. Journal of Endocrinology 128, 175180.CrossRefGoogle ScholarPubMed
Coleman, M. E., Pan, Y.-C. E. & Etherton, T. D. (1991). Identification and NH2-terminal amino acid sequence of three insulin-like growth factor-binding proteins in porcine serum. Biochemical and Biophysical Research Communications 181, 11311136.CrossRefGoogle ScholarPubMed
Coleman, M. E., Russell, L. & Etherton, T. E. (1994). Porcine somatotropin (pST) increases IGF-I mRNA abundance in liver and subcutaneous adipose tissue but not in skeletal muscle of growing pigs. Journal of Animal Science 72, 918924.CrossRefGoogle Scholar
Dardevet, D., Manin, M., Balage, M., Sornet, C. & Grizard, J. (1991). Influence of low-and high-protein diets on insulin and insulin-like growth factor-1 binding to skeletal muscle and liver in the growing rat. British Journal of Nutrition 65, 4760.CrossRefGoogle ScholarPubMed
Dauncey, M. J., Burton, K. A., White, P., Harrison, A. P., Gilmour, R. S., Duchamp, C. & Cattaneo, D. (1994). Nutritional regulation of growth hormone receptor gene expression. FASEB Journal 8, 8188.Google ScholarPubMed
Dauncey, M. J. & Buttle, H. L. (1990). Differences in growth hormone and prolactin secretion associated with environmental temperature and energy intake. Hormone and Metabolic Research 22, 524527.CrossRefGoogle ScholarPubMed
Dauncey, M. J., Rudd, B. T., White, D. A. & Shakespear, R. A. (1993). Regulation of insulin-like growth factor binding proteins in young growing animals by alteration of energy status. Growth Regulation 3, 198207.Google ScholarPubMed
Dauncey, M. J., Shakespear, R. A., Rudd, B. T. & Ingram, D. L. (1990). Variations in somatomedin-C/insulin- like growth factor-I associated with environmental temperature and nutrition. Hormone and Metabolic Research 22, 261264.CrossRefGoogle ScholarPubMed
Davis, S. L., Graf, M., Morrisson, C. A., Hall, T. R. & Swift, P. J. (1992). Identification and partial purification of serum growth hormone binding protein in domestic animal species. Journal of Animal Science 70, 773780.CrossRefGoogle ScholarPubMed
Denver, R. J. & Nicoll, C. S. (1994). Pancreatic hormones differentially regulate insulin-like growth factor (1GF)-I and IGF-binding protein production by primary rat hepatocytes. Journal of Endocrinology 142, 299310.CrossRefGoogle Scholar
Dougherty, K. & Clark, A. R. (1994). Nutrient regulation of insulin gene expression. FASEB Journal 8, 2027.Google Scholar
Evock, C. M., Walton, P. E. & Etherton, T. D. (1990). Effect of GH status on IGF-I and IGF-II concentrations and serum IGF binding profiles in pigs. Journal of Animal Science 68, 19531964.CrossRefGoogle ScholarPubMed
Gilmour, R. S. (1994). The implications of insulin-like growth factor mRNA heterogeneity. Journal of Endocrinology 140, 13.CrossRefGoogle ScholarPubMed
Glassford, J., Flick-Smith, H. & Pell, J. M. (1995). Regulation of insulin-like growth factor type-1 receptor (IGFlR) and insulin receptor (IR) gene expression by nutritional status. Journal of Endocrinology 147, Suppl., O40.Google Scholar
Grant, A. L., Helferich, W. G., Kramer, S. A., Merkel, R. A. & Bergen, W. G. (1991). Administration of growth hormone to pigs alters the relative amount of insulin-like growth factor-1 mRNA in liver and skeletal muscle. Journal of Endocrinology 130, 331338.CrossRefGoogle ScholarPubMed
Guan, X. F., Brameld, J. M. & Buttery, P. J. (1997). Effects of dietary protein levels and porcine growth hormone administration on plasma concentrations of insulin-like growth factor binding proteins in growing pigs. Proceedings of the Nutrition Society 56, 168A.Google Scholar
Harper, J. M. M., Soar, J. B. & Buttery, P. J. (1987). Changes in protein metabolism of ovine primary muscle cultures on treatment with growth hormone, insulin, insulin-like growth factor-I or epidermal growth factor. Journal of Endocrinology 112, 8796.CrossRefGoogle ScholarPubMed
Houston, B. & O'Neill, I. E. (1991). Insulin and growth hormone act synergistically to stimulate insulin-like growth factor-I production by cultured chicken hepatocytes. Journal of Endocrinology 128, 389393.CrossRefGoogle ScholarPubMed
Hsu, C.-J., Kimball, S. R., Antonetti, D. A. & Jefferson, L. S. (1992). Effects of insulin on total RNA, poly(A)+ RNA, and mRNA in primary cultures of rat hepatocytes. American Journal of Physiology 263, E1106E1112.Google ScholarPubMed
Jacoby, D. B., Zilz, N. D. & Towle, H. C. (1989). Sequences within the 5'-flanking region of the S14 gene confer responsiveness to glucose in primary hepatocytes. Journal of Biological Chemistry 264, 1762317626.Google ScholarPubMed
Jones, J. I. & Clemmons, D. R. (1995). Insulin-like growth factors and their binding proteins: Biological actions. Endocrine Reviews 16, 334.Google ScholarPubMed
Kachra, Z., Barash, I., Yannopoulos, C., Khan, M. N., Guyda, H. J. & Posner, B. I. (1991). The differential regulation by glucagon and growth hormone of insulin-like growth factor (IGF)-I and IGF binding proteins in cultured rat hepatocytes. Endocrinology 128, 17231730.CrossRefGoogle ScholarPubMed
Kang, R., Yamada, K., Tanaka, T., Lu, T. & Noguchi, T. (1996). Relationship between concentrations of glycolytic intermediates and expression of the L-type pyruvate kinase gene in cultured hepatocytes. Journal of Biochemistry 119, 162166.CrossRefGoogle ScholarPubMed
Kelley, R. L., Jungst, S. B., Spencer, T. E., Owsley, W. F., Rahe, C. H. & Mulvaney, D. R. (1995). Maternal treatment with somatotropin alters embryonic development and early postnatal growth of pigs. Domestic Animal Endocrinology 12, 8394.CrossRefGoogle ScholarPubMed
Kelly, P. A., Djiane, J., Postel-Vinay, M. C. & Edery, M. (1991). The prolactin/growth hormone receptor family. Endocrinology Reviews 12, 235251.CrossRefGoogle ScholarPubMed
Kelly, P. A., Goujon, L., Dinerstein, H., Esposito, N., Edery, M., Finidori, J. & Posten-Vinay, M. C. (1994). The GH receptor and signal transduction. Hormone Research 42, 133139.CrossRefGoogle ScholarPubMed
Kilberg, M. S., Hutson, R. G. & Laine, R. O. (1994). Amino acid-regulated gene expression in eukaryotic cells. FASEB Journal 8, 1319.Google ScholarPubMed
Li, J., Saunders, J. C., Gilmour, R. S., Silver, M. & Fowden, A. L. (1993). Insulin-like growth factor-II messenger ribonucleic acid expression in fetal tissues of the sheep during late gestation: Effects of cortisol. Endocrinology 132, 20832089.CrossRefGoogle ScholarPubMed
Louveau, I. & Etherton, T. D. (1992). Partial purification of somatotropin receptors from pig liver: they arise from a single somatotropin receptor messenger RNA transcript. Journal of Animal Science 70, 34213428.CrossRefGoogle ScholarPubMed
Luo, Q. J. & MacRae, J. C. (1990). Production of insulin-like growth factor-1 by rat hepatocytes is sensitive to nutrients but not growth hormone. Biochemical Society Transactions 18, 11971198.CrossRefGoogle Scholar
McCusker, R. H., Campion, D. R., Jones, W. K. & Clemmons, D. R. (1985). The insulin-like growth factor-binding proteins of porcine serum: endocrine and nutritional regulation. Endocrinology 125, 501509.CrossRefGoogle ScholarPubMed
Miura, Y., Higashi, Y., Kato, H., Takahashi, S.-I. & Noguchi, T. (1992). Effects of dexamethasone on the production of insulin-like growth factor-I and insulin-like growth factor binding proteins in primary cultures of rat hepatocytes. Bioscience Biotechnology and Biochemistry 56, 13961400.CrossRefGoogle ScholarPubMed
Niimi, S., Hayakawa, T., Tanaka, A. & Ichihara, A. (1991). Glucose regulation of growth hormone receptors in primary cultured rat hepatocytes. Endocrinology 129, 27342739.CrossRefGoogle ScholarPubMed
Oldham, J. M., Martyn, J. A. K., Kirk, S. P., Napier, J. R. & Bass, J. J. (1996). Regulation of type 1 insulin-like growth factor (IGF) receptors and IGF-I mRNA by age and nutrition in ovine skeletal muscles. Journal of Endocrinology 148, 337346.CrossRefGoogle ScholarPubMed
Owens, P. C., Johnson, R. J., Campbell, R. G. & Ballad, F. J. (1990). Growth hormone increases insulin-like growth factor-I (IGF-I) and decreases IGF-II in plasma of growing pigs. Journal of Endocrinology 124, 269275.CrossRefGoogle ScholarPubMed
Phillips, L. S., Goldstein, S. & Pao, C.-I. (1991). Nutrition and somatomedin XXVI. Molecular regulation of IGF-I by insulin in cultured rat hepatocytes. Diabetes 40, 15251530.CrossRefGoogle ScholarPubMed
Prip-Buus, C., Perdereau, D., Foufelle, F., Maury, J., Ferre, P. & Girard, J. (1995). Induction of fatty-acid-synthase gene expression by glucose in primary culture of rat hepatocytes: Dependency upon glucokinase activity. European Journal of Biochemistry 230, 309315.CrossRefGoogle ScholarPubMed
Ramsay, T. G., Chung, I. B., Czenvinski, S. M., McMurtry, J. P., Rosebrough, R. W. & Steele, N. C. (1995). Tissue IGF-I protein and mRNA responses to a single injection of somatotropin. American Journal of Physiology 269, E627E635.Google ScholarPubMed
Rechler, M. M. & Brown, A. L. (1992). Insulin-like growth factor binding proteins: Gene structure and expression. Growth Regulation 2, 5568.Google ScholarPubMed
Rencurel, F., Waeber, G., Antoine, B., Rocchiccioli, F., Maulard, P., Girard, J. & Leturque, A. (1996). Requirement of glucose metabolism for regulation of glucose transporter type 2 (GLUT2) gene expression in liver. Biochemical Journal 314, 903909.CrossRefGoogle ScholarPubMed
Roe, J. A., Haji Baba, A. S., Harper, J. M. M. & Buttery, P. J. (1995). Effects of growth factors and gut regulatory peptides on nutrient uptake in ovine muscle cell cultures. Comparative Biochemistry and Physiology 110A, 107114.CrossRefGoogle ScholarPubMed
Roe, J. A., Harper, J. M. M. & Buttery, P. J. (1989). Protein metabolism in ovine primary muscle cultures derived from satellite cells—effects of selected peptide hormones and growth factors. Journal of Endocrinology 122, 565571.CrossRefGoogle ScholarPubMed
Seve, B., Ballevre, O., Ganier, P., Noblet, J., Prugnaud, J. & Obled, C. (1993). Recombinant porcine somatotropin and dietary protein enhance protein synthesis in growing pigs. Journal of Nutrition 123, 529540.Google ScholarPubMed
Sorensen, M. T., Chaudhuri, S., Louveau, I., Coleman, M. E. & Etherton, T. D. (1992). Growth hormone binding proteins in pig adipose tissue: number, size and effects of pGH treatment on pGH and bGH binding. Domestic Animal Endocrinology 9, 1324.CrossRefGoogle ScholarPubMed
Straus, D. S., Burke, E. J. & Marten, N. W. (1993). Induction of insulin-like growth factor binding protein-1 gene expression in liver of protein-restricted rats and in rat hepatoma cells limited for a single amino acid. Endocrinology 132, 10901100.CrossRefGoogle ScholarPubMed
Sussenbach, J. S., Steenbergh, P. H. & Holthuizen, P. (1992). Structure and expression of the human insulin-like growth factor genes. Growth Regulation 2, 19.Google ScholarPubMed
Thissen, J.-P., Pucilowska, J. B. & Underwood, L. E. (1994). Differential regulation of insulin-like growth factor-I (IGF-I) and IGF binding protein-1 messenger ribonucleic acids by amino acid availability and growth hormone in rat hepatocyte primary culture. Endocrinology 134, 15701576.CrossRefGoogle ScholarPubMed
Trivedi, B. & Daughaday, W. H. (1988). Release of growth hormone binding protein from IM-9 lymphocytes by endopeptidase digestion is dependent on sulfydryl group inactivation. Endocrinology 123, 22012206.CrossRefGoogle Scholar
Uchijima, Y., Takenaka, A., Takahashi, S.-I. & Noguchi, T. (1995). Production of insulin-like growth factors and their binding proteins in primary cultures of rat liver parenchymal and nonparenchymal cells. Bioscience Biotechnology and Biochemistry 58, 15031515.CrossRefGoogle Scholar
van Neste, L., Husman, B., Moller, C., Andersson, G. & Norstedt, G. (1988). Cellular distribution of somatogenic receptors and insulin-like growth factor-I mRNA in the rat liver. Journal of Endocrinology 119, 6974.CrossRefGoogle ScholarPubMed
Vaulont, S. & Kahn, A. (1994). Transcriptional control of metabolic regulation genes by carbohydrates. FASEB Journal 8, 2835.Google ScholarPubMed
Weller, P. A., Dauncey, M. J., Bates, P. C., Brameld, J. M., Buttery, P. J. & Gilmour, R. S. (1994). Regulation of porcine insulin-like growth factor-I and growth hormone receptor mRNA expression by energy status. American Journal of Physiology 266, E776E785.Google ScholarPubMed
Weller, P. A., Dickson, M. C., Huskisson, N. S., Dauncey, M. J., Buttery, P. J. & Gilmour, R. S. (1993). The porcine insulin-like growth factor-I gene: characterization and expression of alternate transcription sites. Journal of Molecular Endocrinology 11, 201211.CrossRefGoogle ScholarPubMed
Weller, H., Hernandez-Sanchez, C., Kamieli, E. & LeRoith, D. (1995). The regulation of IGF-I receptor gene expression. International Journal of Biochemistry and Cell Biology 27, 987994.Google Scholar
Wolverton, C. K., Azain, M. J., Duffy, J. Y., White, M. E. & Ramsay, T. G. (1992). Influence of somatotropin on lipid metabolism and IGF gene expression in porcine adipose tissue. American Journal of Physiology 263, E637E645.Google ScholarPubMed
Zapf, J. (1995). Physiological role of the insulin-like growth factor binding proteins. European Journal of Endocrinology 132, 645654.CrossRefGoogle ScholarPubMed
You have Access
15
Cited by

Send article to Kindle

To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Molecular mechanisms involved in the nutritional and hormonal regulation of growth in pigs
Available formats
×

Send article to Dropbox

To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

Molecular mechanisms involved in the nutritional and hormonal regulation of growth in pigs
Available formats
×

Send article to Google Drive

To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

Molecular mechanisms involved in the nutritional and hormonal regulation of growth in pigs
Available formats
×
×

Reply to: Submit a response

Please enter your response.

Your details

Please enter a valid email address.

Conflicting interests

Do you have any conflicting interests? *