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Mass spectrometric analysis of stable-isotope-labelled amino acid tracers

Published online by Cambridge University Press:  03 August 2018

Tom Preston  and
Christine Slater
Tom Preston
Affiliation:
Scottish Universities Research and Reactor Centre, East Kilbride, Glasgow
Christine Slater
Affiliation:
Scottish Universities Research and Reactor Centre, East Kilbride, Glasgow
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Abstract

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Type
Energy and Protein Metabolism Group Workshop on ‘Application of stable isotopes to nutritional metabolism’
Information
Proceedings of the Nutrition Society , Volume 53 , Issue 2 , July 1994 , pp. 363 - 372
Copyright
Copyright © The Nutrition Society 1994

References

Barrie, A., Bricout, J. & Koziet, J. (1984). Gas chromatography-stable isotope ratio analysis at natural abundance levels. Biomedical Mass Spectrometry 11, 583-588.CrossRefGoogle Scholar
Brookes, S. T., Davies, J. E., Scrimgeour, C. M., Smith, K. & Watt, P. W. (1991). Single cycle analysis of 15N and 13C enrichment in proteins. Proceedings of the 1st Biennial International Conference on Amino Acid Research, Kyoto, 13-19 Aug 1991. Google Scholar
Brookes, S. T. & Milne, E. (1991). Analysis of L-(l-13C)-leucine by continuous flow-isotope ratio mass spectrometry. Clinical Nutrition 10, Special Suppl. 2, p. 48.CrossRefGoogle Scholar
Calder, A. G., Anderson, S. E., Grant, I., McNurlan, M. A. & Garlick, P. J. (1992). The determination of low ds-phenylalanine enrichment (0-002-0-09 atom percent excess), after conversion to phenylethylamine, in relation to protein turnover studies by gas chromatography/electron impact ionisation mass spectrometry. Rapid Communications in Mass Spectrometry 6, 421-424.CrossRefGoogle Scholar
Fearon, K. C. H., McMillan, D. C., Preston, T., Winstanley, F. P., Cruickshank, A. M. & Shenkin, A. (1991). Elevated circulating interleukin-6 is associated with an acute-phase response but reduced fixed hepatic protein synthesis in patients with cancer. Annals of Surgery 213, 26-31.Google Scholar
Hobson, K. A., Alisauskas, R. T. & Clark, R. G. (1993). Stable nitrogen isotope enrichment in avian tissues due to fasting and nutritional stress: implications for isotopic analyses of diet. The Condor 95, 388-394.Google Scholar
Matthews, D. E. & Hayes, J. M. (1978). Isotope-ratio-monitoring gas chromatography-mass spectrometry. Analytical Chemistry 50, 1465-1473.CrossRefGoogle Scholar
Molnar, J. A., Alpert, N. M., Wolfe, M., Burke, J. F. & Young, V. R. (1985). Assessment of skin collagen turnover using l8O. In Substrate and Energy Metabolism in Man, p. A17 [Garrow, J. S. and Halliday, D., editors]. London: John Libbey.Google Scholar
Nier, A. O. (1947). A mass spectrometer for isotope and gas analysis. Review of Scientific Instruments 18, 398-411.CrossRefGoogle ScholarPubMed
Preston, T. (1992). The measurement of stable isotope natural abundance variations. Plant, Cell and Environment 15, 1091-1097.Google Scholar
Preston, T. & McMillan, D. C. (1988). Rapid sample throughput for biomedical stable isotope tracer studies. Biomedical and Environmental Mass Spectrometry 16, 229-235.Google Scholar
Preston, T. & Owens, N. J. P. (1983). Interfacing an automatic elemental analyser with an isotope ratio mass spectrometer: the potential for fully automated total nitrogen and nitrogen-15 analysis. Analyst 108, 971-977.Google Scholar
Preston, T. & Owens, N. J. P. (1985). Preliminary 13C measurements using a gas chromatograph interfaced to an isotope ratio mass spectrometer. Biomedical Mass Spectrometry 12, 510-513.Google Scholar
Preston, T., Robertson, I. & East, B. W. (1984). Simultaneous in vivo measurement of total body nitrogen by neutron-activation analysis and of protein turnover in humans and animals. Analyst 109, 357-359.Google Scholar
Prosser, S. J., Brookes, S. T., Linton, A. & Preston, T. (1991). Rapid, automated analysis of 13C and 18O of CO2 in gas samples by continuous-flow, isotope ratio mass spectrometry. Biological Mass Spectrometry 20, 724-730.Google Scholar
Rieley, G., Collier, R. J., Jones, D. M., Eglington, G., Eakin, P. A. & Fallick, A. E. (1991). Sources of sedimentary lipids deduced from stable carbon-isotope analyses of individual compounds. Nature 353, 425-427.Google Scholar
Schwarcz, H. P. & Schoeninger, M. J. (1991). Stable isotope analyses in human nutritional ecology. Yearbook of Physical Anthropology 34, 283-321.Google Scholar
Silfer, J. A., Engel, M. N., Macko, S. A. & Jumeau, E. J. (1991). Stable carbon isotope analysis of amino acid enantiomers by conventional isotope ratio mass spectrometry and combined gas chromatography/isotope ratio mass spectrometry. Analytical Chemistry 63, 370-374.Google Scholar
Taggart, D. P., McMillan, D. C., Preston, T., Richardson, R., Burns, H. J. G. & Wheatley, D. J. (1991). Effects of cardiac surgery and intraoperative hypothermia on energy expenditure as measured by doubly labelled water. British Journal of Surgery 78, 237-241.CrossRefGoogle ScholarPubMed
Tissot, S., Normand, S., Guilly, R., Pachiaudi, C., Beylot, M., Laville, M., Chen, R., Mornex, R. & Riou, J. P. (1990). Use of a new gas chromatograph isotope ratio mass spectrometer to trace exogenous 13C labelled glucose at a very low level of enrichment in man. Diabetiologia 33, 449-456.Google Scholar
Yarasheski, K. E., Smith, K., Rennie, M. J. & Bier, D. M. (1992). Measurement of muscle protein fractional synthetic rate by capillary gas chromatography/combustion isotope ratio mass spectrometry. Biological Mass Spectrometry 21, 486-490.Google Scholar