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X-ray powder diffraction data for a DACH Pt iodide, cis-[diiodo(1R,2R)-1,2-diaminocyclohexane-κN,κN′] platinum(II)

Published online by Cambridge University Press:  29 February 2012

R. Pažout*
Affiliation:
Central Laboratories, Institute of Chemical Technology Prague, Technická 5, 166 28 Prague 6, Czech Republic
J. Maixner
Affiliation:
Central Laboratories, Institute of Chemical Technology Prague, Technická 5, 166 28 Prague 6, Czech Republic
*
a)Author to whom correspondence should be addressed. Electronic mail: richard.pazout@vscht.cz.

Abstract

X-ray powder diffraction data, unit-cell parameters, and space group for a novel platinum-based anticancer complex cis-[diiodo(1R,2R)-1,2-diaminocyclo-hexane-κN,κN′] platinum(II), Pt(C6H14N2)I2, are presented [a=14.048(4) Å, b=7.588(3) Å, c=11.502(4) Å, β=98.446(5)°, space group C2, cell volume=1212.80 Å3, and Z=4]. All measured lines were indexed and are consistent with the C2 space group. No detectable impurities were observed.

Type
New Diffraction Data
Copyright
Copyright © Cambridge University Press 2010

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References

Abu-Surrah, A. S. and Kettunen, M. (2006). “Platinum group antitumor chemistry: Design and development of new anticancer drugs complementary to cisplatin,” Curr. Med. Chem. CMCHE7 13, 13371357.10.2174/092986706776872970Google Scholar
Boultif, A. and Louër, D. (2004). “Powder pattern indexing with the dichotomy method,” J. Appl. Crystallogr. JACGAR 37, 724731.10.1107/S0021889804014876Google Scholar
Galanski, M., Arion, V. B., Jakupec, M. A., and Keppler, B. K. (2003). “Recent developments in the field of tumor-inhibiting metal complexes,” Curr. Pharm. Des. CPDEFP 9, 2078–89. 10.2174/1381612033454180Google ScholarPubMed
Ho, Y. P., Au-Yeung, S. C. F., and To, K. K. W. (2003). “Platinum-based anticancer agents: Innovative design strategies and biological perspectives,” Med. Res. Rev. ZZZZZZ 23, 633655.10.1002/med.10038CrossRefGoogle ScholarPubMed
Smith, G. S. and Snyder, R. L. (1979). “FN: A criterion for rating powder diffraction patterns and evaluating the reliability of powder indexing,” J. Appl. Crystallogr. JACGAR 12, 6065.10.1107/S002188987901178XCrossRefGoogle Scholar