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Synthesis and X-ray diffraction data of 1-N-(4-pyridylmethyl)amino naphthalene

Published online by Cambridge University Press:  29 February 2012

H. A. Camargo ,
J. A. Henao ,
D. F. Amado  and
V. V. Kouznetsov
H. A. Camargo
Affiliation:
Grupo de Investigación en Química Estructural (GIQUE), Centro de Investigación en Biomoléculas, (CIBIMOL), Escuela de Química, Facultad de Ciencias, Universidad Industrial de Santander, A.A. 678, Carrera 27, Calle 9, Ciudadela Universitaria, Bucaramanga, Colombia
J. A. Henao*
Affiliation:
Grupo de Investigación en Química Estructural (GIQUE), Centro de Investigación en Biomoléculas, (CIBIMOL), Escuela de Química, Facultad de Ciencias, Universidad Industrial de Santander, A.A. 678, Carrera 27, Calle 9, Ciudadela Universitaria, Bucaramanga, Colombia
D. F. Amado
Affiliation:
Laboratorio de Química Orgánica y Biomolecular (LQOBio), Centro de Investigación en Biomoléculas, (CIBIMOL), Escuela de Química, Facultad de Ciencias, Universidad Industrial de Santander, A.A. 678, Carrera 27, Calle 9, Ciudadela Universitaria, Bucaramanga, Colombia
V. V. Kouznetsov
Affiliation:
Laboratorio de Química Orgánica y Biomolecular (LQOBio), Centro de Investigación en Biomoléculas, (CIBIMOL), Escuela de Química, Facultad de Ciencias, Universidad Industrial de Santander, A.A. 678, Carrera 27, Calle 9, Ciudadela Universitaria, Bucaramanga, Colombia
*
a)Author to whom correspondence should be addressed. Electronic mail: jahenao@uis.edu.co
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Abstract

1-N-(4-pyridylmethyl)amino naphtalene was synthesized by means of a reaction of alpha-naphthylamine, 4-pyridylcarboxyaldehyde, in anhydrous ethanol to obtainN-(4-pyridylen)-alpha-naphthylamine and that was reduced with NaBH4 to produce the wanted compound. The X-ray powder diffraction pattern for the new compound 1-N-(4-pyrydylmethyl)amino naphtalene was obtained. This compound crystallizes in a monoclinic system with refined unit cell parameters a=10.375(5) Å, b=17.665(6) Å, c=5.566(2) Å, β=100.11(3), and V=1004.3(5) Å3, with space group P2/m (No. 10).

Keywords

secondary aminesterbinafineX-ray powder diffraction
Type
New Diffraction Data
Information
Powder Diffraction , Volume 25 , Issue 1 , March 2010 , pp. 72 - 74
Copyright
Copyright © Cambridge University Press 2010

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References

Boultif, A. and Loüer, D. (2004). “Indexing of powder diffraction patterns of low symmetry lattices by successive dichotomy method,” J. Appl. Crystallogr. JACGAR 37, 724–731 .10.1107/S0021889804014876CrossRefGoogle Scholar
Buhrke, V., Jenkins, R., and Smith, D. (1998). Preparation of Specimens for X-ray Fluorescence and X-ray Diffraction Analysis (Wiley, New York), pp. 141–142.Google Scholar
de Wolff, P. M. (1968). “A simplified criterion for the reliability of a powder pattern indexing,” J. Appl. Crystallogr. JACGAR 1, 108–113 .10.1107/S002188986800508XCrossRefGoogle Scholar
Favre, B. and Ryder, N. S. (1997). “Differential inhibition of fungal and mammalian squalene epoxidases by the benzylamine SDZ SBA 586 in comparison with the allylamine terbinafine,” Arch. Biochem. Biophys. ABBIA4 340, 265–269 .10.1006/abbi.1997.9908Google Scholar
Kouznetsov, V. V., Vargas, L. Y., Sortino, M., Vásquez, Y., Gupta, M., Freile, M., Enriz, R., and Zacchino, S. (2008). “Antifungal and cytotoxic activities of some N-substituted aniline derivates bearing a hetaryl fragment,” Bioorg. Med. Chem. BMECEP 16, 794–809 .10.1016/j.bmc.2007.10.034CrossRefGoogle ScholarPubMed
Krise, J. and Oliyai, R. (2007). Prodrugs of Amines. Biotechnology: Pharmaceutical Aspects (Springer, New York), pp. 101–131.Google Scholar
Laugier, J. and Bochu, B. (2002). CHEKCELL. LMGP-Suite suite of programs for the interpretation of X-ray experiments 〈http://www.inpg.fr/LMGP〉 and 〈http://www.ccp14.ac.uk/tutorial/lmgp/〉.Google Scholar
Miguell, A. D., Hubberd, C. R., and Stalick, J. K. (1981). NBS* AIDS80: A FORTRAN program for crystallographic data evaluation. National Bureau of Standards (USA), Tech. Note 1141.Google Scholar
Smith, G. S. and Snyder, R. L. (1979). “FN: A criterion for rating powder diffraction patterns and evaluating the reliability of powder-pattern indexing,” J. Appl. Crystallogr. JACGAR 12, 60–65 .10.1107/S002188987901178XGoogle Scholar
Vargas, L. Y., Castelli, M. V., Kouznetsov, V. V., Urbina, J. M., López, S. N., Sortino, M., Enriz, R. D., Ribas, J. C., and Zacchino, S. A. (2003). “In vitro antifungal activity of new series of homoallylamines and related compounds with inhibitory properties of the synthesis of fungal cell wall polymers,” Bioorg. Med. Chem. BMECEP 11, 1531–1550 .10.1016/S0968-0896(02)00605-3CrossRefGoogle Scholar