Hostname: page-component-76fb5796d-45l2p Total loading time: 0 Render date: 2024-04-28T03:36:58.873Z Has data issue: false hasContentIssue false
  • English
  • Français

Studies on the resistance of rats to the nematode Nippostrongylus muris (Yokogawa, 1920). II. Different routes of immunization and test infection

Published online by Cambridge University Press:  06 April 2009

G. C. Hunter  and
L. C. Leigh
G. C. Hunter
Affiliation:
The Rowett Research Institute, Bucksburn, Aberdeen
L. C. Leigh
Affiliation:
The Rowett Research Institute, Bucksburn, Aberdeen
Get access Rights & Permissions [Opens in a new window]

Extract

Rats were given immunizing doses of N. muris larvae by three different routes: orally and intraperitoneally and through the skin. The immunized rats survived a test infection which was lethal for non-immune rats. Only the rats immunized by the skin route showed skin sensitivity.

Type
Research Article
Information
Parasitology , Volume 51 , Issue 3-4 , November 1961 , pp. 353 - 356
Copyright
Copyright © Cambridge University Press 1961

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Africa, C. M. (1931). Studies on the host relations of N. muris with special reference to age resistance and acquired immunity. J. Parasit. 18, 1–13.CrossRefGoogle Scholar
Chandler, A. C. (1937 a). Studies on the nature of immunity to intestinal helminths. V. Experiments on the role of the skin in parenteral immunity, and further experiments on passive immunisation in Nippostrongylus infections in rats. Amer. J. Hyg. 26, 292–308.Google Scholar
Chandler, A. C. (1937 b). Studies on the nature of immunity to intestinal helminths. VI. General resumé and discussion. Amer. J. Hyg. 26, 309–21.Google Scholar
Chase, M. W. (1946). Inhibition of experimental drug allergy by prior feeding of the sensitizing agent. Proc. Soc. Exp. Biol., N.Y. 61, 257.CrossRefGoogle ScholarPubMed
Hunter, G. C. & Leigh, L. C. (1961). Studies on the resistance of rats to the nematode N. muris (Yokogawa, 1920). 1. Dosage-Mortality relationship. Parasitology, 51, 347–351.CrossRefGoogle Scholar
Leigh, L. C. (1956). Methods for the culture and collection of N. muris. J. Inst. Sci. Tech. 2, 21–3.Google Scholar
Schwartz, B., Alicata, J. E. & Lucker, J. T. (1931). Resistance of rats to superinfections with a nematode, N. muris, and an apparently similar resistance of horses to superinfection with nematodes. J. Wash. Acad. Sci. 21, 259–61.Google Scholar
Taliaferro, W. H. & Sarles, M. P. (1939). The cellular reactions in the skin, lungs and intestine of normal and immune rats after infection with N. muris. J. Infect. Dis. 64, 157–92.CrossRefGoogle Scholar
Yokogawa, S. (1920). A new nematode from the rat. J. Parasit. 7, 29–33.CrossRefGoogle Scholar
Yokogawa, S. (1922). The development of Heligmosomum muris Yokogawa, a nematode from the intestine of the wild rat. Parasitology, 14, 127–66.CrossRefGoogle Scholar