Hostname: page-component-848d4c4894-75dct Total loading time: 0 Render date: 2024-06-07T18:35:06.189Z Has data issue: false hasContentIssue false
  • English
  • Français

Patterns of milk transmission of Strongyloides ratti

Published online by Cambridge University Press:  06 April 2009

P. A. G. Wilson ,
Maureen Cameron  and
D. S. Scott
P. A. G. Wilson
Affiliation:
University of Edinburgh, Department of Zoology, West Mains Road, Edinburgh EH9 3JT
Maureen Cameron
Affiliation:
University of Edinburgh, Department of Zoology, West Mains Road, Edinburgh EH9 3JT
D. S. Scott
Affiliation:
University of Edinburgh, Department of Zoology, West Mains Road, Edinburgh EH9 3JT
Get access Rights & Permissions [Opens in a new window]

Summary

Eight days after mother rats were injected with 4000 infective larvae of Strongyloides ratti at different stages of lactation the numbers of adult worms in their intestines were uniformly low (< 3% of the dose) compared with unmated controls (mean = 25%). Those in their litters varied from 12% on day 5 to a maximum of 47% on day 17 post partum. These data, which do not correlate with lactational performance, imply that parasite movements in lactating rats are controlled by qualitative, not quantitative, consequences of humoral events. The numbers of worms in litters are concluded to be the result of the interaction of dynamic determinants of larval routes in the mother and changes in the suitability of the neonatal gut as an environment for worm development. The timing of events leading to milk-borne infection is defined. Injected larvae were closely synchronized in their movements, which were completed in 36 h. Larvae experimentally diverted into the mother's tissues during her first lactation were not available for the infection of a second litter.

Type
Research Article
Information
Parasitology , Volume 77 , Issue 1 , August 1978 , pp. 87 - 96
Copyright
Copyright © Cambridge University Press 1978

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Baldwin, R. L. & Yang, Y. T. (1974). Enzymatic and metabolic changes in the development of lactation. In Lactation: a Comprehensive Treatise, vol. 1 (ed. Larson, B. L. and Smith, V. R.), pp. 349–411. New York and London: Academic Press.Google Scholar
Denham, D. A. (1966). Infections with Trichinella spiralis passing from mother to filial mice pre and postnatally. Journal of Helminthology 40, 291–6.CrossRefGoogle ScholarPubMed
Douglas, J. R. & Baker, N. F. (1959). The chronology of experimental transuterine infection with Toxocara canis (Werner 1782) in the dog. Journal of Parasitology 45, (4 Sect. 2) 43.Google Scholar
Grosvenor, C. E. & Mena, F. (1974). Neural and hormonal control of milk secretion and milk ejection. In Lactation: a Comprehensive Treatise, vol. 1 (ed. Larson, B. L. and Smith, V. R.), pp. 227–76. New York and London: Academic Press.Google Scholar
Lyons, E., Drudge, J. H. & Tolliver, S. C. (1970). Strongyloides larvae in milk of sheep and cattle. Modern Veterinary Practice 51, 65–8.Google Scholar
Lyons, E., Drudge, J. H. & Tolliver, S. C. (1973). On the life cycle of Strongyloides westeri in the equine. Journal of Parasitology 59, 780–7.CrossRefGoogle ScholarPubMed
Moncol, D. J. (1975). Supplement to the life history of Strongyloides ransomi Schwartz & Alicata, 1930 (Nematoda: Strongyloididae) of pigs. Proceedings of the Helminthological Society of Washington 42, 86–92.Google Scholar
Olsen, O. W. & Lyons, E. T. (1965). Life cycle of Uncinaria lucasi Stiles, 1901 (Nematoda: Ancylostomatidae) of fur seals, Callorhinus ursinus Linn. on the Pribilof Islands, Alaska. Journal of Parasitology 51, 689–700.CrossRefGoogle ScholarPubMed
Schmelzle, M. & Stoye, M. (1976). On the migration of larvae of Ancylostoma caninum: studies on lactating dogs. Zeitschrift für Parasitenkunde 50, 219–20.Google Scholar
Stewart, T. B., Stone, W. M. & Marti, O. G. (1976). Strongyloides ransomi: prenatal and transmammary infection of pigs of sequential litters from dams experimentally exposed as weanlings. American Journal of Veterinary Research 37, 451–4.Google ScholarPubMed
Stoye, M. (1973). Untersuchungen über die Möglichkeit pränateler und galaktogener Infec-tionen mit Ancylostoma caninum Ercolani 1859 (Ancylostomidae) beim Hund. Zentralblatt Veterinaermed (B) 20, 1–39.CrossRefGoogle Scholar
Swerczek, T., Nielsen, S. W. & Helmboldt, C. F. (1971). Transmammary passage of Toxocara cati in the cat. American Journal of Veterinary Research 32, 89–92.Google ScholarPubMed
Warren, E. G. (1971). Observations on the migration and development of Toxocara vitulorum in natural and experimental hosts. International Journal for Parasitology 1, 85–99.CrossRefGoogle ScholarPubMed
Wilson, P. A. G. (1977). The effect of the suckling stimulus on the migration of Strongyloides ratti in lactating rats. Parasitology 75, 233–9.CrossRefGoogle ScholarPubMed
Wilson, P. A. G., Cameron, M. & Scott, D. S. (1978). Strongyloides ratti in virgin female rats: studies of oestrous cycle effects and general variability. Parasitology 76, 221–7.CrossRefGoogle ScholarPubMed
Wilson, P. A. G., Gentle, M. & Scott, D. S. (1976 a). Milk-borne infection of rats with Strongyloides ratti and Nippostrongylus brasiliensis. Parasitology 72, 355–60.CrossRefGoogle ScholarPubMed
Wilson, P. A. G., Gentle, M. & Scott, D. S. (1976 b). Dynamic determinants of the route of larval Strongyloides ratti in lactating rats and the control of experimental error in quantitative studies of milk transmission of skin-penetrating roundworms. Parasitology 73, 398–406.CrossRefGoogle ScholarPubMed
Zamirdin, M. & Wilson, P. A. G. (1974). Strongyloides ratti: relative importance of maternal sources of infection. Parasitology 69, 445–53.CrossRefGoogle ScholarPubMed